Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix

A Noncanonical mu-1A-Binding Motif in the N Terminus of HIV-1 Nef Determines Its Ability To Downregulate Major Histocompatibility Complex Class I in T Lymphocytes

(2012) S. Iijima et al.   JOURNAL OF VIROLOGY

Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function

(2012) Pieter J Meuwissen et al.   Retrovirology

Mechanisms of HIV-1 Nef Function and Intracellular Signaling

(2011) John L. Foster et al.   Journal of Neuroimmune Pharmacology

ADP Ribosylation Factor 1 Activity Is Required To Recruit AP-1 to the Major Histocompatibility Complex Class I (MHC-I) Cytoplasmic Tail and Disrupt MHC-I Trafficking in HIV-1-Infected Primary T Cells

(2011) E. R. Wonderlich et al.   JOURNAL OF VIROLOGY

Secretion Modification Region-Derived Peptide Disrupts HIV-1 Nef's Interaction with Mortalin and Blocks Virus and Nef Exosome Release

(2011) M. N. Shelton et al.   JOURNAL OF VIROLOGY

The Identification of a Small Molecule Compound That Reduces HIV-1 Nef-Mediated Viral Infectivity Enhancement

(2011) Nopporn Chutiwitoonchai et al.   PLoS One

Structure, dynamics, and Hck interaction of full-length HIV-1 Nef

(2011) Jinwon Jung et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2

(2011) Kevin C Olivieri et al.   Retrovirology

HIV-Nef and AIDS pathogenesis: are we barking up the wrong tree?

(2011) Andreas S. Baur   TRENDS IN MICROBIOLOGY

Genetic Characterization of HIV Type 1 Nef-Induced Vesicle Secretion

(2010) Syed A. Ali et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Small Molecule Inhibition of HIV-1–Induced MHC-I Down-Regulation Identifies a Temporally Regulated Switch in Nef Action

(2010) Jimmy D. Dikeakos et al.   MOLECULAR BIOLOGY OF THE CELL

Systemic Administration of Antiretrovirals Prior to Exposure Prevents Rectal and Intravenous HIV-1 Transmission in Humanized BLT Mice

(2010) Paul W. Denton et al.   PLoS One

Self-association of the Lentivirus protein, Nef

(2010) Youn Tae Kwak et al.   Retrovirology

At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis

(2009) Robert T. Youker et al.   BIOCHEMICAL JOURNAL

HIV-1 Nef Dimerization Is Required for Nef-Mediated Receptor Downregulation and Viral Replication

(2009) Jerrod A. Poe et al.   JOURNAL OF MOLECULAR BIOLOGY

An MHC-I Cytoplasmic Domain/HIV-1 Nef Fusion Protein Binds Directly to the μ Subunit of the AP-1 Endosomal Coat Complex

(2009) Rajendra Kumar Singh et al.   PLoS One

Competition Model for Upregulation of the Major Histocompatibility Complex Class II-Associated Invariant Chain by Human Immunodeficiency Virus Type 1 Nef

(2008) R. S. Mitchell et al.   JOURNAL OF VIROLOGY

Functional Characterization of the Human Immunodeficiency Virus Type 1 Nef Acidic Domain

(2008) L. L. Baugh et al.   JOURNAL OF VIROLOGY

HIV-1 Nef: at the crossroads

(2008) John L Foster et al.   Retrovirology

Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice

(2008) Paul W Denton et al.   PLOS MEDICINE