The expression and relaxant effect of bitter taste receptors in human bronchi

Different Phenolic Compounds Activate Distinct Human Bitter Taste Receptors

(2013) Susana Soares et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Cellular and Molecular Basis of Bitter Tastant-Induced Bronchodilation

(2013) Cheng-Hai Zhang et al.   PLOS BIOLOGY

TAS2R activation promotes airway smooth muscle relaxation despite β2-adrenergic receptor tachyphylaxis

(2012) Steven S. An et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea

(2012) Ville Pulkkinen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Caffeine relaxes smooth muscle through actin depolymerization

(2012) Tracy Tazzeo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics

(2012) Christina Orsmark-Pietras et al.   EUROPEAN RESPIRATORY JOURNAL

Reply to: Activation of BK channels may not be required for bitter tastant–induced bronchodilation

(2012) Steven S An et al.   NATURE MEDICINE

Activation of BK channels may not be required for bitter tastant–induced bronchodilation

(2012) Cheng-Hai Zhang et al.   NATURE MEDICINE

Taste receptor signalling - from tongues to lungs

(2011) S. C. Kinnamon   Acta Physiologica

Roflumilast inhibits the release of chemokines and TNF-α from human lung macrophages stimulated with lipopolysaccharide

(2011) A Buenestado et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of bitter tastants on human bronchi

(2011) Alyn H Morice et al.   NATURE MEDICINE

Epac as a novel effector of airway smooth muscle relaxation

(2010) Sara S. Roscioni et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Phosphoinositide 3-Kinase   Regulates Airway Smooth Muscle Contraction by Modulating Calcium Oscillations

(2010) H. Jiang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

(2010) Deepak A Deshpande et al.   NATURE MEDICINE

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

(2009) Wolfgang Meyerhof et al.   CHEMICAL SENSES

Motile Cilia of Human Airway Epithelia Are Chemosensory

(2009) A. S. Shah et al.   SCIENCE

Tonic activity of Gα-gustducin regulates taste cell responsivity

(2008) Tod R. Clapp et al.   FEBS LETTERS

Interleukin 13 Increases Contractility of Murine Tracheal Smooth Muscle by a Phosphoinositide 3-kinase p110 -Dependent Mechanism

(2008) H. S. M. Farghaly et al.   MOLECULAR PHARMACOLOGY

Bitter Taste Receptors Influence Glucose Homeostasis

(2008) Cedrick D. Dotson et al.   PLoS One