Article
Immunology
Constanza Salinas, Gabriel Espinosa, Natalia Morales, Claudio Henriquez, Gabriel Moran, Gonzalo Gajardo, Rafael A. Burgos, Benjamin Uberti
Summary: Obesity and insulin dysregulation are common conditions in equid populations. This study found that metabolic status and oral glucose administration can alter immune function, particularly phagocytosis and oxidative burst, in horses.
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
(2022)
Article
Cell Biology
Melissa Parny, Jose Bernad, Melissa Prat, Marie Salon, Agnes Aubouy, Elsa Bonnafe, Agnes Coste, Bernard Pipy, Michel Treilhou
Summary: Ziram affects macrophage functions and polarization, increasing phagocytosis and inducing oxidative stress which leads to the expression of antioxidant genes. Ziram modulates macrophages to M2-like anti-inflammatory phenotype through zinc, potentially associated with various diseases.
CELL BIOLOGY AND TOXICOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Urszula Lisiecka, Piotr Brodzki, Anna Smiech, Janusz Kocki, Marcin Czop, Lukasz Adaszek, Stanislaw Winiarczyk
Summary: This study investigated the differences in innate immune cell markers between healthy female dogs and those with mammary tumors, finding an increase in CD11b lymphocytes in tumors with epithelial origin. The results suggest the potential of certain innate immune cells to be supportive diagnostic markers in canine mammary tumors.
Article
Agriculture, Dairy & Animal Science
Andrzej Zmuda, Urszula Lisiecka, Katarzyna Dudek, Roman Dabrowski, Boleslaw Gasiorek, Stanislaw Winiarczyk, Krzysztof Kostro
Summary: This study assessed the phagocytic activity and oxygen metabolism in mink with chronic subclinical AMDV infection and measured the intensity of inflammatory processes based on serum amyloid A (SAA) concentration. The results showed a significant decrease in phagocytic activity and oxygen metabolism in AMDV-infected mink compared to the control group. Additionally, SAA levels were significantly higher in the infected group. Monitoring serum SAA levels may help assess mink health and detect asymptomatic inflammation caused by AMDV infection.
Article
Agriculture, Dairy & Animal Science
Indre Poskiene, Renata Gruodyte, Jurgita Autukaite, Vida Juozaitiene, Ramunas Antanaitis
Summary: The study found significant changes in blood parameters of Arabian horses during endurance races, with faster speeds. The FEI considers equestrian endurance racing as the second largest discipline in the world. Arabian horses are recognized as the leading breed in endurance competitions with significant differences in muscle tissue structure.
Review
Neurosciences
Congqin Li, Yong Wang, Ying Xing, Jing Han, Yuqian Zhang, Anjing Zhang, Jian Hu, Yan Hua, Yulong Bai
Summary: Microglia play a crucial role in phagocytosis in the central nervous system, maintaining brain homeostasis and clearing toxic factors associated with neurological disorders.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Klaudia Szymczak, Margery G. H. Pelletier, James M. Mackay, DeAnne Reid, Peter C. W. Gaines
Summary: Neutrophils are important regulators of innate immunity, and a small molecule antagonist called RIST4721 can effectively inhibit their chemotaxis in ex vivo-cultured mouse bone marrow cells stimulated by KC. RIST4721-treated neutrophils exhibited enhanced phagocytosis and reactive oxygen species production, confirming the specificity of the drug. These findings suggest that RIST4721 could be a potential treatment for various inflammatory conditions mediated by neutrophils.
Article
Biochemistry & Molecular Biology
Francesca Arfuso, Maria Rizzo, Claudia Giannetto, Elisabetta Giudice, Roberta Cirincione, Giovanni Cassata, Luca Cicero, Giuseppe Piccione
Summary: This study aimed to evaluate the changes in serum oxidant and antioxidant parameters, as well as the levels of homocysteine and muscle enzymes, in regularly trained athletic horses during official races of different distances. The results showed that exercise had an effect on oxidative stress markers, homocysteine, and muscle enzymes, while the race distance did not have a significant impact on these parameters.
Article
Agriculture, Dairy & Animal Science
Hannah C. Valigura, Jessica L. Leatherwood, Rafael E. Martinez, Sharon A. Norton, Sarah H. White-Springer
Summary: Dietary supplementation with 21 g/d of a Saccharomyces cerevisiae fermentation product may help mitigate cellular stress following a single, prolonged submaximal exercise bout in young horses after 8 weeks of treatment.
JOURNAL OF ANIMAL SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Charlotte Schrurs, Sarah Blott, Guillaume Dubois, Emmanuelle Van Erck-Westergren, David S. S. Gardner
Summary: Using a stride tracking device, this study objectively measures and compares the stride lengths of racehorses categorized as sprinters or stayers. The results show that there are significant differences in stride length between these two categories, even before they compete in races. The study also finds that stride length during training cannot predict racing success, but stayers tend to have better race results than sprinters. This objective data on stride characteristics can be helpful for trainers in selecting appropriate races for each racehorse.
Article
Multidisciplinary Sciences
Jing Wang, Negin Jalali Motlagh, Cuihua Wang, Gregory R. Wojtkiewicz, Stephan Schmidt, Cindy Chau, Radha Narsimhan, Enrico G. Kuellenberg, Cindy Zhu, Jenny Linnoila, Zhenwei Yao, John W. Chen
Summary: D-mannose has been found to have anti-inflammatory effects in reducing neuroinflammation and may be a low-cost treatment option for inflammatory neurological diseases such as multiple sclerosis.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Neurosciences
Megan P. Feeney, Yaqian Xu, Matthew Surface, Hiral Shah, Nora Vanegas-Arroyave, Amanda K. Chan, Elizabeth Delaney, Serge Przedborski, James C. Beck, Roy N. Alcalay
Summary: The impact of COVID-19 on the health and day-to-day activities of people with Parkinson's disease (PwPD) is not well understood, but a survey showed significant effects on PD symptoms and management practices. During the pandemic, the use of telehealth increased significantly, with almost half of PwPD expressing a desire to continue using telehealth after the pandemic ends.
NPJ PARKINSONS DISEASE
(2021)
Article
Immunology
Youcheng Yang, Jiajun Chen, Linqing Lu, Zizheng Xu, Feng Li, Minxuan Yang, Jun Li, Li Lin, Zhendong Qin
Summary: Studies have shown that goose erythrocytes have the ability to phagocytose and exhibit antimicrobial activity. They can produce reactive oxygen species and inducible nitric oxide synthase in response to bacterial stimulation. Furthermore, goose erythrocytes show powerful antibacterial activity and up-regulate the expression of inflammatory factors and antioxidant enzymes.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Aritz Saitua, Cristina Castejon-Riber, Francisco Requena, David Arguelles, Natalie Calle-Gonzalez, Antonia Sanchez de Medina, Ana Munoz
Summary: This study found that the changes in locomotion patterns occurring during exercise on a water treadmill can persist during terrestrial locomotion, and horses with low fitness levels may experience fatigue after exercise on the water treadmill.
Editorial Material
Hematology
Laurent A. Messonnier
Summary: Although sickle cell disease (SCD) is related to a single point mutation, there is extreme variability in the clinical presentation among patients. Genetic variants may contribute to this variability. In this study, Dosunmu-Ogunbi et al. highlighted the importance of a genetic variant affecting mitochondrial function in the cardiovascular pathophysiology of SCD. Their findings provide important insights and perspectives for patient management.
Article
Veterinary Sciences
Witold Kedzierski, Iwona Janczarek, Sylwestr Kowalik, Monika Jamiol, Tatiana Wawak, Grzegorz Borsuk, Monika Przetacznik
JOURNAL OF EQUINE VETERINARY SCIENCE
(2020)
Review
Agriculture, Dairy & Animal Science
Alicja Rakowska, Anna Cywinska, Lucjan Witkowski
Article
Veterinary Sciences
Witkowska-Pilaszewicz Olga, Cywinska Anna, Michlik-Polczynska Katarzyna, Czopowicz Michal, Strzelec Katarzyna, Biazik Anna, Parzeniecka-Jaworska Marta, Crisman Mark, Witkowski Lucjan
Summary: In ponies of different classes, all biochemical parameters, except total protein concentration, showed significant differences. The most significant difference was found in blood lactate concentrations, which were higher in the smallest ponies (class A). Muscle enzymes and urea were higher, while triglycerides and creatinine were lower than normal values for equine species in all groups of ponies. Blood lactate concentration was higher only in class A ponies compared to normal values for horses.
BMC VETERINARY RESEARCH
(2021)
Article
Agriculture, Dairy & Animal Science
Katarzyna Miazga, Johan Joubert, Megan Sinclair, Anna Cywinska
Article
Agriculture, Dairy & Animal Science
Sylwester Kowalik, Anna Wisniewska, Witold Kedzierski, Iwona Janczarek
Article
Veterinary Sciences
O. Witkowska-Pilaszewicz, J. Grzedzicka, J. Sen, M. Czopowicz, M. Zmigrodzka, A. Winnicka, A. Cywinska, C. Carter
Summary: This study aimed to investigate the influence of physical activity on peripheral blood cortisol concentration, and found that cortisol concentration significantly increased after training and competition, especially more intensive after competition. More challenging physical activities associated with competition events in race and endurance horses result in a greater stress response, highlighting the need to limit these events to ensure animal welfare. Performance horses adapt more readily to physical activity, experiencing less increase in cortisol concentration after the race.
PREVENTIVE VETERINARY MEDICINE
(2021)
Article
Veterinary Sciences
Witold Kedzierski, Sylwester Kowalik, Wioleta Mojsym, Iwona Janczarek, Ewelina Tkaczyk
Summary: The study aimed to evaluate the influence of different exercise intensities on blood plasma activin A and decorin concentrations in horses. Results showed that despite differences in exercise intensity, plasma decorin concentration remained unchanged, and activin A tended to decrease in endurance horses only. The exercise-induced changes in plasma activin A concentrations correlated with the covered distance.
JOURNAL OF EQUINE VETERINARY SCIENCE
(2021)
Article
Cell Biology
Olga Witkowska-Pilaszewicz, Rafal Pingwara, Jaroslaw Szczepaniak, Anna Winnicka
Summary: Clenbuterol is gaining popularity for weight loss and bodybuilding, but is prohibited in anti-doping control. Research suggests that clenbuterol can inhibit the inflammatory process. Beta 2-adrenoceptor stimulation has enhanced anti-inflammatory properties in well-trained horses, but can create a pro-inflammatory environment in inexperienced horses.
Article
Agriculture, Dairy & Animal Science
Agnieszka Chalabis-Mazurek, Jose Luis Valverde Piedra, Siemowit Muszynski, Ewa Tomaszewska, Sylwia Szymanczyk, Sylwester Kowalik, Marcin B. Arciszewski, Anna Zacharko-Siembida, Tomasz Schwarz
Summary: This study evaluated the impact of partially substituting wheat and barley with maize or modern rye varieties on the concentration of heavy metals in feed offered to pigs and in pig tissues. The results showed that new rye varieties, especially hybrid variety, could be a potential alternative source of cereal grains for pig nutrition.
Review
Microbiology
Rachel Goodman-Davis, Marianna Figurska, Anna Cywinska
Summary: Diarrhea in foals is a significant issue that may be influenced by microbiota manipulation, but caution should be exercised in using prebiotics and probiotics.
Article
Agriculture, Dairy & Animal Science
W. Kedzierski, I Sadok, S. Kowalik, I Janczarek, M. Staniszewska
Summary: This study evaluated the effects of two different types of exercise (short-time intense exercise and endurance exercise) on tryptophan metabolism in horses of the same breed. The results showed that both types of exercise led to an increase in tryptophan metabolites, especially kynurenic acid, which had beneficial effects on the mental state of the horses.
Article
Genetics & Heredity
Ewelina Maculewicz, Bozena Antkowiak, Oktawiusz Antkowiak, Andrzej Mastalerz, Agnieszka Bialek, Anna Cywinska, Anna Borecka, Kinga Huminska-Lisowska, Aleksandra Garbacz, Katarzyna Lorenz, Ewa Szarska, Monika Michalowska-Sawczyn, Lukasz Dziuda, Pawel Cieszczyk
Summary: In this study, no relationship was found between obesity parameters and IL-6 gene polymorphisms in a homogeneous group of young, male military professionals. The results suggest that even with a genetic predisposition, the impact on individuals with mild obesity can be reduced by changes in lifestyle.
Article
Agriculture, Dairy & Animal Science
Justyna Sokolowska, Anna Cywinska, Martyna Puchalska
Summary: This study demonstrates the differences in the microscopic characteristics of C thyrocytes among dogs, pigs, cattle, and horses, providing a reference for further research on the biology of C thyrocytes in different physiological and pathological conditions. The morphology, distribution pattern, and fraction of C thyrocytes varied among the four domestic species studied. Although the total number of C thyrocyte profiles and their localization within the thyroid lobe were comparable, each species displayed its own unique characteristics. Studies on C thyrocytes in domestic animals are limited.
Article
Chemistry, Medicinal
Magdalena Staniszewska, Sylwester Kowalik, Ilona Sadok, Witold Kedzierski
Summary: The intensity of exercise affects the catabolism of tryptophan, with intense exercise leading to increased concentrations of lactic acid, kynurenine, xanthurenic acid, and nicotinamide, while decreasing tryptophan levels. These changes have limited impact on the health status of exercised horses.
Article
Agriculture, Dairy & Animal Science
K. Dziki-Michalska, K. Tajchman, S. Kowalik, M. Bogdaszewski
Summary: The study demonstrated a significant positive correlation between plasma cortisol level and bodyweight in farmed male fallow deer. Additionally, a negative correlation was found between weight gain and changes in cortisol levels. Therefore, selecting calmer animals with lower cortisol fluctuations for breeding could contribute to greater stability in weight gain.
SOUTH AFRICAN JOURNAL OF ANIMAL SCIENCE
(2021)
Article
Veterinary Sciences
R. Mischke, K. Rumstedt, S. O. Hungerbuehler, K. Rohn, M. Schmicke
Summary: Contrast-enhanced ultrasound (CEUS) can provide an additional tool for the diagnosis of hypothyroidism in dogs and support its differentiation from non-thyroidal illness. Sedation has limited impact on CEUS results.
RESEARCH IN VETERINARY SCIENCE
(2024)
Review
Veterinary Sciences
Lucas Petitemberte de Souza, William Borges Domingues, Eduardo Bierhals Blodorn, Leandro da Silva Nunes, Hadassa Gabriela Ortiz, Eliza Rossi Komninou, Vinicius Farias Campos
Summary: This study performed a systematic review of the differential expression of sperm microRNAs in bulls related to fertility. A total of 182 unique differentially expressed miRNAs were identified, among which 49 miRNAs were found in common between at least two studies. The results suggest that miRNAs such as miR-10a, -10b, -103, -15b, -122, -125b, -126-5p, -151-5p, -193a-5p, -196a, -27a-5p, and -99b may serve as potential universal biomarkers for assessing the reproductive potential of males.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Wonhee Cha, Katinca Fungbrant, Giulio Grandi, Ylva Persson
Summary: This study investigated the prevalence and development of hair loss in outdoor cattle in Sweden. It found a relatively high hair loss rate, with the occurrence of hair loss increasing over time during winters, suggesting a contagious etiology. The study also identified preventative delousing before November, keeping animals clean, and maintaining small group sizes as effective measures to reduce the risk of hair loss, while older age and access to bedding materials increased the risk.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Sheeba Thomas, David Francis Lappin, David Bennett, Christopher Nile, Marcello Pasquale Riggio
Summary: This study found that Feline odontoclastic resorptive lesion (FORL) can be divided into two subgroups, with FORL-1 subgroup having a less diverse oral microbiome and higher levels of proinflammatory cytokines and chemokines, which may be associated with the severity and activity of the disease.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
S. L. Gayathri, M. Bhakat, T. K. Mohanty
Summary: This study used infrared thermography (IRT) to identify mastitis in Sahiwal cows. The results showed significant differences in the mean values of udder and teat surface temperature between healthy, subclinical mastitis (SCM), and clinical mastitis (CM) cases during different seasons. IRT is an efficient tool for the early identification of subclinical mastitis.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Zeynep Ozdemir Kutahya, Busra Aslan Akyol, Kubra Deliklitas, Cengiz Gokbulut
Summary: In this study, the pharmacokinetic behavior of Eprinomectin was studied in two different goat breeds. The results showed no significant differences in plasma concentration between the breeds, but the clearance from the body may vary. High concentration of Eprinomectin in feces is beneficial against gastrointestinal parasites but poses an ecotoxicological risk to the environment.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Mohammad Ashrafzadeh-Shiraz, Mousa Tavassoli, Bahram Dalir-Naghadeh, Alireza Sazmand
Summary: This study evaluated the efficacy of fenbendazole and ivermectin on strongyles and Parascaris sp. infecting adult riding horses in different regions of Iran. The results demonstrated varying degrees of resistance of these parasites to both anthelminthics. It emphasizes the urgency of educating horse owners about the importance of a test-and-treatment strategy and suggests evaluating the efficacy of different anthelminthics to choose the most effective treatment in each region.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Moises Gonzalvez, Clara Munoz-Hernandez
Summary: The study evaluated the use of R software in research articles addressing the study of wildlife, showing an increasing trend in the number of publications over time and a wide geographical distribution globally.
RESEARCH IN VETERINARY SCIENCE
(2024)
