Article
Environmental Sciences
Daniel Arismendi, Constanza Alanis, Pablo Richter, Alfonso H. Paredes
Summary: This study evaluated the effects of exposure to TCS in female rats and found that medium-term exposure to TCS did not significantly alter the estrous cycle, but caused alterations in growth, sex hormone levels, and some elements in rat serum.
Article
Environmental Sciences
Charles S. da Costa, Thiago F. Oliveira, Leandro C. Freitas-Lima, Alessandra S. Padilha, Maiara Krause, Maria Tereza W. D. Carneiro, Breno S. Salgado, Jones B. Graceli
Summary: This study evaluated the effects of cadmium exposure on the HPG axis and various abnormalities in female rats, finding that cadmium exposure led to metabolic and reproductive dysfunctions, indicating that cadmium disrupts HPG axis function, leading to features of PCOS and POF.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Jingyi Song, Xiaochen Ma, Feixue Li, Jing Liu
Summary: This study found that gestational exposure of female mice to multiple pyrethroids at recommended safe doses had irreversible adverse effects on the ovaries in female offspring. The exposure regulated the expression of miRNAs during early developmental stages, disrupting key biological processes and signaling pathways governing follicular development and ovarian functions. However, lactational and peripubertal exposure to pyrethroid mixture did not significantly affect follicular development and ovarian functions.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Niedson Correia de Lima Junior, Juliana Franco Camilo, Pamella Rodrigues do Carmo, Marcelle Novaes de Andrade, Bernardo Ferreira Braz, Ricardo Erthal Santelli, Lycia de Brito Gitirana, Andrea Claudia Freitas Ferreira, Denise Pires de Carvalho, Leandro Miranda-Alves, Glaecir Roseni Mundstock Dias
Summary: Subacute exposure to lead acetate disrupts thyroid gland function in both sexes, leading to changes in learning and memory abilities.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
David A. Geier, Mark R. Geier
Summary: A study using NHANES data found that 82% of the tested individuals in the United States had detectable concentrations of glyphosate in their urine. There was a significant inverse correlation between glyphosate concentrations and total testosterone and total estradiol concentrations, but no correlation with sex hormone binding globulin concentrations.
Article
Environmental Sciences
Xue Yang, Qingping Xue, Ying Wen, Yichao Huang, Yi Wang, Gaga Mahai, Tong Yan, Yanjun Liu, Tao Rong, Yixin Wang, Da Chen, Shuqin Zeng, Chun-Xia Yang, Xiong-Fei Pan
Summary: The present study found associations between polycyclic aromatic hydrocarbon (PAH) exposure and metabolic syndrome (MetS) and its components. Participants with higher PAH exposure had increased prevalence of MetS and related symptoms. Lifestyle factors such as smoking, alcohol consumption, and diet quality may modify the associations between PAH exposure and MetS.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Engineering, Environmental
Marion Albouy, Yoann Deceuninck, Virginie Migeot, Manon Doumas, Antoine Dupuis, Nicolas Venisse, Pascale Pierre Engene, Bruno Veyrand, Thomas Geny, Philippe Marchand, Bruno Le Bizec, Emmanuelle Bichon, Pascal Carato
Summary: Exposure of pregnant women to endocrine disruptor compounds, such as parabens and bisphenol A, is a concern for fetal development. This study examined the occurrence of these compounds and their degradation products in drinking water samples from a French cohort study. The results showed that parabens, bisphenols, and their degradation products were detected in drinking water, with the highest detection frequencies for monochlorinated degradation products. This analytical approach provides insights into the human chemical exposome.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Tiago Gabriel Correia, Vanessa Aparecida Rocha Oliveira Vieira, Amanda de Moraes Narcizo, Ricardo Andrade Zampieri, Lucile Maria Floeter-Winter, Renata Guimaraes Moreira
Summary: This study found that after exposure to aluminum and manganese, female ray-finned teleost fish during the vitellogenic phase showed endocrine disruption and impaired reproductive capacity, with the presence of manganese exacerbating the accumulation of aluminum in gills.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Environmental Sciences
R. Wesley Flynn, Tyler D. Hoskins, Michael Iacchetta, Chloe de Perre, Linda S. Lee, Jason T. Hoverman, Maria S. Sepulveda
Summary: PFAS are contaminants of concern due to their persistence, potential to bioaccumulate, and toxicity. Limited data on dietary PFAS uptake and adverse effects in terrestrial species hinder ecological risk assessment. Laboratory experiment on tiger salamanders showed PFOS resulted in biomagnification, while PFAS altered growth and body condition without increasing liver size at environmentally relevant doses. The results demonstrate the impact of dietary exposure and accumulation of PFAS on amphibians' fitness-related traits and trophic transfer in terrestrial food webs.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biochemistry & Molecular Biology
Liselott Kallsten, Radwa Almamoun, Paula Pierozan, Erik Nylander, Kalliroi Sdougkou, Jonathan W. Martin, Oskar Karlsson
Summary: This study found that di-n-butyl phthalate (DBP) exposure can lead to persistent effects on testosterone synthesis and spermatogenesis in adult male mice, resulting in decreased testosterone levels. The study also revealed increased levels of key cells and proteins, including steroidogenic enzymes, oxidative stress markers, and germ cell markers, in response to DBP exposure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Junjie Ao, Yongjie Liu, Weifeng Tang, Jun Zhang
Summary: This study investigates the potential effects and mechanisms of bisphenol S (BPS) exposure on human colon mucosal epithelial cells. The results show that BPS exposure increases the production of pro-inflammatory cytokines, destroys the tight junctions of the cells, and affects neurotransmitters. These findings suggest that BPS exposure may disrupt the balance of the gut-brain axis, leading to inflammatory cytokine production and tight junction destruction.
Article
Toxicology
Davidson Peruci Moreira, Yves Moreira Ribeiro, Camila Stephanie Ferreira, Samyra Maria dos Santos Nassif Lacerda, Elizete Rizzo
Summary: This study aimed to investigate the effects of chronic exposure to environmentally relevant ACE concentrations on multiple reproductive parameters in zebrafish. The results showed that ACE impaired the reproductive performance of zebrafish, including a decrease in egg and sperm quantity and quality, as well as an imbalance of sex steroids and prostaglandin E-2 levels. These findings indicate the impact of ACE on the reproductive ability of aquatic species.
ARCHIVES OF TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Teresa Peluso, Valeria Nittoli, Carla Reale, Immacolata Porreca, Filomena Russo, Luca Roberto, Antonia Giacco, Elena Silvestri, Massimo Mallardo, Mario De Felice, Concetta Ambrosino
Summary: Early life exposure to Endocrine Disruptor Chemicals (EDCs), such as the pesticide Chlorpyrifos (CPF), has been found to affect thyroid activity, glucose metabolism, and lipid metabolism. In this study, the researchers investigated the effects of CPF exposure on the metabolism and signaling of thyroid hormones (THs) and lipid/glucose metabolism in mice. They found that these processes were altered in males that were exposed to CPF, leading to hypothyroidism and systemic hyperglycemia. Additionally, the researchers discovered that CPF affected glucose metabolism and TH levels through the modulation of FOXO1 activity in liver cells. These findings highlight the importance of considering the intergenerational and sex-specific effects of CPF exposure on metabolic homeostasis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Leslie-Anne Merleau, Izia Larrigaldie, Oceane Bousquet, Severine Devers, Matthieu Keller, Charlotte Lecureuil, Joel Meunier
Summary: This study tested the effect of pyriproxyfen exposure on maternal care in the European earwig, and found that the authorized doses of pyriproxyfen are likely to have limited effects on the populations of the European earwig.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Clara Bodelon, Gretchen L. Gierach, Elizabeth E. Hatch, Emily Riseberg, Amy Hutchinson, Meredith Yeager, Dale P. Sandler, Jack A. Taylor, Robert N. Hoover, Zongli Xu, Linda Titus, Julie R. Palmer, Rebecca Troisi
Summary: This study explored blood DNA methylation in women exposed and unexposed to prenatal diethylstilbestrol (DES). The results showed that DNA methylation levels at 10 CpG sites in six candidate genes were significantly associated with prenatal DES exposure. These findings suggest that in utero DES exposure may be associated with differential blood DNA methylation levels, which could mediate the increased risk of several adverse health outcomes observed in exposed women.
ENVIRONMENTAL RESEARCH
(2023)
Article
Biochemical Research Methods
Thomas A. Darde, Pierre Gaudriault, Remi Beranger, Clement Lancien, Annaelle Caillarec-Joly, Olivier Sallou, Nathalie Bonvallot, Cecile Chevrier, Severine Mazaud-Guittot, Bernard Jegou, Olivier Collin, Emmanuelle Becker, Antoine D. Rolland, Frederic Chalmel
Article
Environmental Sciences
Dorothy Nakiwala, Hugo Peyre, Barbara Heude, Jonathan Y. Bernard, Remi Beranger, Remy Slama, Claire Philippat
ENVIRONMENTAL HEALTH
(2018)
Article
Environmental Sciences
Remi Beranger, Emilie M. Hardy, Celia Dexet, Laurence Guldner, Cecile Zaros, Alexandre Nougadere, Marie-Astrid Metten, Cecile Chevrier, Brice M. R. Appenzeller
ENVIRONMENT INTERNATIONAL
(2018)
Article
Environmental Sciences
Remi Beranger, Elise Billoir, John R. Nuckols, Jeffrey Blain, Maurice Millet, Marie-Laure Bayle, Bruno Combourieu, Thierry Philip, Joachim Schuz, Beatrice Fervers
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2019)
Article
Public, Environmental & Occupational Health
Noriane Cognez, Charline Warembourg, Cecile Zaros, Marie-Astrid Metten, Ghislaine Bouvier, Ronan Garlantezec, Marie-Aline Charles, Remi Beranger, Cecile Chevrier
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2019)
Article
Public, Environmental & Occupational Health
Remi Beranger, Emilie M. Hardy, Anne-Claire Binter, Marie-Aline Charles, Cecile Zaros, Brice M. R. Appenzeller, Cecile Chevrier
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2020)
Review
Environmental Sciences
Jeanne Sandrine Ongono, Remi Beranger, Amaria Baghdadli, Marion Mortamais
ENVIRONMENTAL RESEARCH
(2020)
Article
Obstetrics & Gynecology
Elodie Marguillier, Remi Beranger, Ronan Garlantezec, Jean Leveque, Linda Lassel, Chloe Rousseau, Vincent Lavoue, Maela Le Lous
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2020)
Article
Environmental Sciences
Feng-Jiao Peng, Emilie M. Hardy, Remi Beranger, Sakina Mezzache, Nasrine Bourokba, Philippe Bastien, Jing Li, Cecile Zaros, Cecile Chevrier, Paul Palazzi, Jeremie Soeur, Brice M. R. Appenzeller
ENVIRONMENTAL POLLUTION
(2020)
Article
Environmental Sciences
Isabelle Enderle, Nathalie Costet, Noriane Cognez, Cecile Zaros, Julien Caudeville, Ronan Garlantezec, Cecile Chevrier, Alexandre Nougadere, Blandine De Lauzon-Guillain, Maela Le Lous, Remi Beranger
Summary: The study suggests a potential influence of residential exposure to prochloraz and some herbicides on preeclampsia risk, especially for women exposed to prochloraz near their homes. However, no significant association was found between dietary exposure to pesticide residues and preeclampsia.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Aurelie M. N. Danjou, Olivia Perol, Astrid Coste, Elodie Faure, Remi Beranger, Helen Boyle, Elodie Belladame, Leny Grassot, Matthieu Dubuis, Johan Spinosi, Liacine Bouaoun, Aude Flechon, Louis Bujan, Veronique Drouineaud, Florence Eustache, Isabelle Berthaut, Jeanne Perrin, Florence Brugnon, Barbara Charbotel, Joachim Schuz, Beatrice Fervers
Summary: Testicular germ cell tumours (TGCT) are the most common cancer in young men in developed countries, and their incidence has doubled globally over the past 40 years. This study in France found a positive association between domestic use of pesticides, particularly fungicides, during early development and the risk of adult TGCT and non-seminoma subtypes.
ENVIRONMENTAL HEALTH
(2021)
Article
Psychiatry
Jeanne Sandrine Ongono, Cecile Michelon, Remi Beranger, Emmanuelle Cadot, Valentin Simoncic, Julie Loubersac, Marion Mortamais, Amaria Baghdadli
Summary: This study aimed to analyze the associations between early residential proximity to agricultural crops, a proxy of pesticide exposure, and adaptive behaviors in children with ASD. The results showed that an increase in crop acreage was significantly associated with a decrease in communication scores in children without intellectual disability, during both pregnancy and the first two years of life. No association was found in children with intellectual disabilities, providing insights for future research on understanding ASD phenotypes.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Nursing
Cecile Marie, Ronan Garlantezec, Remi Beranger, Anne-Sophie Ficheux
Summary: Based on a literature review, clinical practice guidelines are proposed for informing healthcare professionals about the use and health effects of cosmetics, especially among pregnant and lactating women and young children. Recommendations include reducing the frequency and amount of cosmetic products used, preferring simple and fragrance-free products, and avoiding industrial wipes for children.
JOURNAL OF MIDWIFERY & WOMENS HEALTH
(2022)
Article
Nursing
Estelle Michinov, Gael Robin, Brivael Hemon, Remi Beranger, Marielle Boissart
Summary: This study investigated the stress levels among French student nurses and the impact of personal resources on their well-being. The results showed that self-efficacy played a major role in determining stress and well-being, and these effects were partially mediated by emotional awareness.
NURSE EDUCATION IN PRACTICE
(2024)
Article
Public, Environmental & Occupational Health
Cecile Chevrier, Remi Beranger
CURRENT ENVIRONMENTAL HEALTH REPORTS
(2018)
Article
Reproductive Biology
Lei Gong, Siyi Jiang, Jia Tian, Yong Li, Wansu Yu, Lubo Zhang, Daliao Xiao
Summary: Exposure to gestational diabetes mellitus during pregnancy can lead to the development of a neonatal brain hypoxia/ischemia-sensitive phenotype. The PTEN/AKT/mTOR/autophagy signaling pathway plays a role in this process.
REPRODUCTIVE TOXICOLOGY
(2024)
Article
Reproductive Biology
Sudipta Dutta, Kirthiram K. Sivakumar, John W. Erwin, Jone A. Stanley, Joe A. Arosh, Robert J. Taylor, Sakhila K. Banu
Summary: This study found that exposure to hexavalent chromium disrupts follicle development and causes apoptosis by altering epigenetic marks in the ovary.
REPRODUCTIVE TOXICOLOGY
(2024)
Article
Reproductive Biology
Yuxin Li, Xianzhi He, Bin Sun, Nannan Hu, Jiamin Li, Ruolan You, Feiyan Tao, Lei Fang, Yuanyuan Li, Qingfeng Zhai
Summary: This study investigated the toxic effects and mechanism of beta-CYP and EMB on the reproductive system of female rats. The results showed that exposure to these pesticides led to changes in hormone and gene expression in the hypothalamic-pituitary-ovarian axis, as well as alterations in oxidative damage indicators. The findings support the evaluation of the adverse effects of pesticide exposure on reproductive health in greenhouse operations.
REPRODUCTIVE TOXICOLOGY
(2024)
Article
Reproductive Biology
Ran Lee, Won-Young Lee, Hyun-Jung Park
Summary: This study investigates the toxicity of diuron on fetal mouse testes and finds that diuron has a negative impact on the development of fetal Leydig cells, while not affecting germ cells and Sertoli cells.
REPRODUCTIVE TOXICOLOGY
(2024)