Structural similarities and differences between the human and the mouse pancreas

Quantitative analysis of mouse pancreatic islet architecture by serial block-face SEM

(2015) C.R. Pfeifer et al.   JOURNAL OF STRUCTURAL BIOLOGY

Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet

(2014) J. Molina et al.   DIABETES

New insights into the role of connexins in pancreatic islet function and diabetes

(2014) Nikki L. Farnsworth et al.   FEBS LETTERS

Type 1 diabetes in mice and men: gene expression profiling to investigate disease pathogenesis

(2014) Linda Yip et al.   IMMUNOLOGIC RESEARCH

Using pancreas tissue slices for in situ studies of islet of Langerhans and acinar cell biology

(2014) Anja Marciniak et al.   Nature Protocols

Of rodents and men: Species-specific glucose regulation and type 2 diabetes research

(2014) P. Charukeshi Chandrasekera   ALTEX-Alternatives to Animal Experimentation

Immunohistochemical Study of α- and β-Cell Distribution in Human Pancreatic Langerhans Islets of Various Types

(2013) A. E. Proshchina et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell

(2013) Jiun T. Low et al.   DIABETOLOGIA

Functional Plasticity of the Human Infant β-Cell Exocytotic Phenotype

(2013) Jocelyn E. Manning Fox et al.   ENDOCRINOLOGY

Minireview: Intraislet Regulation of Insulin Secretion in Humans

(2013) Guy A. Rutter et al.   MOLECULAR ENDOCRINOLOGY

Opie’s hypothesis revisited: Acute pancreatitis due to bile reflux into the pancreas

(2013) J. Matthias Löhr et al.   PANCREATOLOGY

Quantitative Analysis of Pancreatic Polypeptide Cell Distribution in the Human Pancreas

(2013) Xiaojun Wang et al.   PLoS One

Glucose-Stimulated Calcium Dynamics in Islets of Langerhans in Acute Mouse Pancreas Tissue Slices

(2013) Andraž Stožer et al.   PLoS One

Regional Differences in Islet Distribution in the Human Pancreas - Preferential Beta-Cell Loss in the Head Region in Patients with Type 2 Diabetes

(2013) Xiaojun Wang et al.   PLoS One

Perinatal Bisphenol A Exposure and Adult Glucose Homeostasis: Identifying Critical Windows of Exposure

(2013) Jingli Liu et al.   PLoS One

The Relationship between Membrane Potential and Calcium Dynamics in Glucose-Stimulated Beta Cell Syncytium in Acute Mouse Pancreas Tissue Slices

(2013) Jurij Dolenšek et al.   PLoS One

The ductal origin of structural and functional heterogeneity between pancreatic islets

(2013) Claudia Merkwitz et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Three-Dimensional Analysis of the Islet Vasculature

(2012) Y. El-Gohary et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Regulation of Insulin Secretion in Human Pancreatic Islets

(2012) Patrik Rorsman et al.   Annual Review of Physiology

Maintenance of  -Cell Maturity and Plasticity in the Adult Pancreas: Developmental Biology Concepts in Adult Physiology

(2012) M. Szabat et al.   DIABETES

 -Cell Mass and Turnover in Humans: Effects of obesity and aging

(2012) Y. Saisho et al.   DIABETES CARE

Differentiating neural crest stem cells induce proliferation of cultured rodent islet beta cells

(2012) G. Grouwels et al.   DIABETOLOGIA

TCF7L2 promotes beta cell regeneration in human and mouse pancreas

(2012) L. Shu et al.   DIABETOLOGIA

3-D imaging and illustration of the perfusive mouse islet sympathetic innervation and its remodelling in injury

(2012) Y.-C. Chiu et al.   DIABETOLOGIA

Distinctions Between the Islets of Mice and Men: Implications for New Therapies for Type 1 and 2 Diabetes

(2012) Claresa Levetan et al.   Endocrine Practice

Novel Approaches to Studying the Role of Innervation in the Biology of Pancreatic Islets

(2012) Rayner Rodriguez-Diaz et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Pancreatic Beta Cells in Very Old Mice Retain Capacity for Compensatory Proliferation

(2012) Miri Stolovich-Rain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Formation of a Human β-Cell Population within Pancreatic Islets Is Set Early in Life

(2012) Brigid E. Gregg et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Murine models for pharmacological studies of the metabolic syndrome

(2012) Lyne Fellmann et al.   PHARMACOLOGY & THERAPEUTICS

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

(2012) R. Rodriguez-Diaz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantification of islet size and architecture

(2012) German Kilimnik et al.   Islets

Formation of Pancreatic Islets Involves Coordinated Expansion of Small Islets and Fission of Large Interconnected Islet-like Structures

(2011) Junghyo Jo et al.   BIOPHYSICAL JOURNAL

Innervation Patterns of Autonomic Axons in the Human Endocrine Pancreas

(2011) Rayner Rodriguez-Diaz et al.   Cell Metabolism

Pancreatic alpha cell mass in European subjects with type 2 diabetes

(2011) J. C. Henquin et al.   DIABETOLOGIA

Differences between Human and Rodent Pancreatic Islets

(2011) Michael J. MacDonald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pancreatic ductal cells in development, regeneration, and neoplasia

(2011) Maximilian Reichert et al.   JOURNAL OF CLINICAL INVESTIGATION

Diabetes and pancreatic cancer

(2011) Donghui Li   MOLECULAR CARCINOGENESIS

Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans

(2011) Rayner Rodriguez-Diaz et al.   NATURE MEDICINE

Impaired Spleen Formation Perturbs Morphogenesis of the Gastric Lobe of the Pancreas

(2011) Andreas Hörnblad et al.   PLoS One

Altered Islet Composition and Disproportionate Loss of Large Islets in Patients with Type 2 Diabetes

(2011) German Kilimnik et al.   PLoS One

Aging induces a distinct gene expression program in mouse islets

(2011) Matthew M. Rankin et al.   Islets

An improved protocol for optical projection tomography imaging reveals lobular heterogeneities in pancreatic islet and β-cell mass distribution

(2011) Andreas Hörnblad et al.   Islets

Glucose-dependent blood flow dynamics in murine pancreatic islets in vivo

(2010) Lara R. Nyman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cell cycle control of β-cell replication in the prenatal and postnatal human pancreas

(2010) Christina U. Köhler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Epithelial dynamics of pancreatic branching morphogenesis

(2010) A. Villasenor et al.   DEVELOPMENT

Unique Arrangement of  - and  -Cells in Human Islets of Langerhans

(2010) D. Bosco et al.   DIABETES

‘Giving and taking’: endothelial and β-cells in the islets of Langerhans

(2010) Daniel Eberhard et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Islet architecture: A comparative study

(2010) Abraham Kim et al.   Islets

Pancreatic islet plasticity: Interspecies comparison of islet architecture and composition

(2010) Donald J. Steiner et al.   Islets

The pancreatic β-cell in the islet and organ community

(2009) Daniel Eberhard et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Age-Dependent Decline in  -Cell Proliferation Restricts the Capacity of  -Cell Regeneration in Mice

(2009) S.-I. Tschen et al.   DIABETES

Adaptive  -Cell Proliferation Is Severely Restricted With Advanced Age

(2009) M. M. Rankin et al.   DIABETES

No mantle formation in rodent islets—The prototype of islet revisited

(2009) Michael Kharouta et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice

(2009) X. Wu et al.   DIABETOLOGIA

β-cell development and turnover during prenatal life in humans

(2009) Juris J Meier et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Endocrine Cell Clustering During Human Pancreas Development

(2009) Jongmin Jeon et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Islet Formation during the Neonatal Development in Mice

(2009) Kevin Miller et al.   PLoS One

Glucose Metabolism, Islet Architecture, and Genetic Homogeneity in Imprinting of [Ca2+]i and Insulin Rhythms in Mouse Islets

(2009) Craig S. Nunemaker et al.   PLoS One

The physiology of rodent beta-cells in pancreas slices

(2008) M. Rupnik   Acta Physiologica

Postnatal Expansion of the Pancreatic  -Cell Mass Is Dependent on Survivin

(2008) Y. Jiang et al.   DIABETES

Glucose Metabolism In Vivo in Four Commonly Used Inbred Mouse Strains

(2008) E. D. Berglund et al.   DIABETES

 -Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of  -Cell Mass in Humans

(2008) J. J. Meier et al.   DIABETES

Pancreatic β-cell mass in European subjects with type 2 diabetes

(2008) J. Rahier et al.   DIABETES OBESITY & METABOLISM

Ghrelin-producing epsilon cells in the developing and adult human pancreas

(2008) K. M. Andralojc et al.   DIABETOLOGIA

Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts

(2008) A. Wojtusciszyn et al.   DIABETOLOGIA

Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets

(2008) Lara R. Nyman et al.   JOURNAL OF CLINICAL INVESTIGATION

Noninvasive in vivo imaging of pancreatic islet cell biology

(2008) Stephan Speier et al.   NATURE MEDICINE

Nerve Plexus Invasion in Pancreatic Cancer

(2008) Isamu Makino et al.   PANCREAS

Unusual fusion between ventral and dorsal primordia causes anomalous pancreaticobiliary junction

(2008) Hiroyuki Tadokoro et al.   PATHOLOGY INTERNATIONAL

The anatomic location of pancreatic cancer is a prognostic factor for survival

(2008) Avo Artinyan et al.   HPB

Carcinomas of the ventral and dorsal pancreas exhibit different patterns of lymphatic spread

(2007) Hirohisa Kitagawa   Frontiers in Bioscience-Landmark