New insights into the role of connexins in pancreatic islet function and diabetes

Decreasing Cx36 Gap Junction Coupling Compensates for Overactive KATPChannels to Restore Insulin Secretion and Prevent Hyperglycemia in a Mouse Model of Neonatal Diabetes

(2014) Linda M. Nguyen et al.   DIABETES

Connexin 36 mediates blood cell flow in mouse pancreatic islets

(2013) Kurt W. Short et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis

(2013) Lindsey E. Padgett et al.   Annals of the New York Academy of Sciences

Connexin 30.2 is expressed in mouse pancreatic beta cells

(2013) C. Coronel-Cruz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Teplizumab (Anti-CD3 mAb) Treatment Preserves C-Peptide Responses in Patients With New-Onset Type 1 Diabetes in a Randomized Controlled Trial: Metabolic and Immunologic Features at Baseline Identify a Subgroup of Responders

(2013) K. C. Herold et al.   DIABETES

Glucose-stimulated insulin secretion: the hierarchy of its multiple cellular and subcellular mechanisms

(2013) Paolo Meda et al.   DIABETOLOGIA

Lipotoxicity disrupts incretin-regulated human β cell connectivity

(2013) David J. Hodson et al.   JOURNAL OF CLINICAL INVESTIGATION

Hyperglycemia downregulates Connexin36 in pancreatic islets via the upregulation of ICER-1/ICER-1γ

(2013) Jacques-Antoine Haefliger et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Regulation of connexin36 gap junction channels byn-alkanols and arachidonic acid

(2013) Alina Marandykina et al.   JOURNAL OF PHYSIOLOGY-LONDON

Learning Theories Reveal Loss of Pancreatic Electrical Connectivity in Diabetes as an Adaptive Response

(2013) Pranay Goel et al.   PLoS One

Connexin36 (Cx36) expression and protein detection in the mouse carotid body and myenteric plexus

(2012) Monica Frinchi et al.   ACTA HISTOCHEMICA

Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice

(2012) C. P. F. Carvalho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Calmodulin dependent protein kinase increases conductance at gap junctions formed by the neuronal gap junction protein connexin36

(2012) Cristiane del Corsso et al.   BRAIN RESEARCH

The In Vivo  -to- -Cell Chat Room: Connexin Connections Matter

(2012) P. Meda   DIABETES

Islet  -Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model

(2012) S. A. Tersey et al.   DIABETES

Connexin-36 Gap Junctions Regulate In Vivo First- and Second-Phase Insulin Secretion Dynamics and Glucose Tolerance in the Conscious Mouse

(2012) W. S. Head et al.   DIABETES

Connexins and β-cell functions

(2012) Valentina Cigliola et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus

(2012) Muhammad Sajid Hamid Akash et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cx36 Is a Target of Beta2/NeuroD1, Which Associates with Prenatal Differentiation of Insulin-producing β Cells

(2012) Rachel Nlend Nlend et al.   JOURNAL OF MEMBRANE BIOLOGY

PPAR-γ Activation Restores Pancreatic Islet SERCA2 Levels and Prevents β-Cell Dysfunction under Conditions of Hyperglycemic and Cytokine Stress

(2012) Tatsuyoshi Kono et al.   MOLECULAR ENDOCRINOLOGY

The Intercellular Synchronization of Ca2+ Oscillations Evaluates Cx36-Dependent Coupling

(2012) Sabine Bavamian et al.   PLoS One

EphB signaling inhibits gap junctional intercellular communication and synchronized contraction in cultured cardiomyocytes

(2011) Maki Ishii et al.   BASIC RESEARCH IN CARDIOLOGY

Glucose- and Hormone-Induced cAMP Oscillations in  - and  -Cells Within Intact Pancreatic Islets

(2011) G. Tian et al.   DIABETES

Loss of Inverse Relationship Between Pulsatile Insulin and Glucagon Secretion in Patients With Type 2 Diabetes

(2011) B. A. Menge et al.   DIABETES

Defects in beta cell Ca2+ signalling, glucose metabolism and insulin secretion in a murine model of KATP channel-induced neonatal diabetes mellitus

(2011) R. K. P. Benninger et al.   DIABETOLOGIA

The gap junction life cycle

(2011) James W. Smyth et al.   HEART RHYTHM

Connexins protect mouse pancreatic β cells against apoptosis

(2011) Philippe Klee et al.   JOURNAL OF CLINICAL INVESTIGATION

Gap junctions and other mechanisms of cell-cell communication regulate basal insulin secretion in the pancreatic islet

(2011) R. K. P. Benninger et al.   JOURNAL OF PHYSIOLOGY-LONDON

Gap junction permeability: selectivity for anionic and cationic probes

(2010) G. Kanaporis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets

(2010) C. P. F. Carvalho et al.   DIABETOLOGIA

Glucose Suppression of Glucagon Secretion

(2010) Sylvain J. Le Marchand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative stress and beta-cell dysfunction

(2010) Gisela Drews et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Connexins: a myriad of functions extending beyond assembly of gap junction channels

(2009) Hashem A Dbouk et al.   Cell Communication and Signaling

Connexins, Diabetes and the Metabolic Syndrome

(2009) Romain Hamelin et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins

(2009) Francisco J. del Castillo et al.   HUMAN MOLECULAR GENETICS

Dopamine-Stimulated Dephosphorylation of Connexin 36 Mediates AII Amacrine Cell Uncoupling

(2009) W. W. Kothmann et al.   JOURNAL OF NEUROSCIENCE

β-Cell deterioration during diabetes: what's in the gun?

(2009) R. Paul Robertson   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Gap Junction Coupling and Calcium Waves in the Pancreatic Islet

(2008) Richard K.P. Benninger et al.   BIOPHYSICAL JOURNAL

Lack of “Hemichannel” Activity in Insulin-Producing Cells

(2008) Eliana Scemes et al.   CELL COMMUNICATION AND ADHESION

Glucose-Induced Cyclic AMP Oscillations Regulate Pulsatile Insulin Secretion

(2008) Oleg Dyachok et al.   Cell Metabolism

A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells

(2008) Kerstin Wellershaus et al.   EXPERIMENTAL CELL RESEARCH

Cx36 makes channels coupling human pancreatic β-cells, and correlates with insulin expression

(2008) Véronique Serre-Beinier et al.   HUMAN MOLECULAR GENETICS

Connexins, pannexins, innexins: novel roles of “hemi-channels”

(2008) Eliana Scemes et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY