Activated-farnesoid X receptor (FXR) expressed in human sperm alters its fertilising ability

Treatment with the natural FXR agonist chenodeoxycholic acid reduces clearance of plasma LDL whilst decreasing circulating PCSK9, lipoprotein(a) and apolipoprotein C-III

(2017) M. Ghosh Laskar et al.   JOURNAL OF INTERNAL MEDICINE

Bile acids and male fertility: From mouse to human?

(2017) Lauriane Sèdes et al.   MOLECULAR ASPECTS OF MEDICINE

Activation of the Farnesoid X-receptor in breast cancer cell lines results in cytotoxicity but not increased migration potential

(2016) Noura Alasmael et al.   CANCER LETTERS

Bile Acid Alters Male Mouse Fertility in Metabolic Syndrome Context

(2015) Aurélie Vega et al.   PLoS One

Farnesoid X receptor immunolocalization in reproductive tissues of adult female rabbits

(2014) Arely Anaya-Hernández et al.   ACTA HISTOCHEMICA

Farnesoid X receptor: Acting through bile acids to treat metabolic disorders

(2014) Y. Zhang   DRUGS OF THE FUTURE

Steroid receptors and their ligands: Effects on male gamete functions

(2014) Saveria Aquila et al.   EXPERIMENTAL CELL RESEARCH

Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice

(2014) Marine Baptissart et al.   HEPATOLOGY

Identification of G protein-coupled estrogen receptor in human and pig spermatozoa

(2014) V. Rago et al.   JOURNAL OF ANATOMY

Perturbation of bile acid homeostasis is an early pathogenesis event of drug induced liver injury in rats

(2013) Makoto Yamazaki et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Mitochondrial Citrate Carrier (CIC) Is Present and Regulates Insulin Secretion by Human Male Gamete

(2012) Anna R. Cappello et al.   ENDOCRINOLOGY

Sperm metabolism in pigs: a role for peroxisome proliferator-activated receptor gamma (PPAR )

(2012) M. Santoro et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Testosterone and farnesoid X receptor agonist INT-747 counteract high fat diet-induced bladder alterations in a rabbit model of metabolic syndrome

(2012) Annamaria Morelli et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Effects of nuclear receptor transactivation on steroid hormone synthesis and gene expression in porcine Leydig cells

(2012) Matthew A. Gray et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Red wine consumption may affect sperm biology: The effects of different concentrations of the phytoestrogen Myricetin on human male gamete function

(2012) Saveria Aquila et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Glucose and Insulin Induction of Bile Acid Synthesis

(2011) Tiangang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human sperm physiology: Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) influence sperm metabolism and may be involved in the pathophysiology of varicocele-associated male infertility

(2011) Carmela Guido et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The nuclear receptor FXR is expressed in pancreatic β-cells and protects human islets from lipotoxicity

(2010) Iuliana Ristea Popescu et al.   FEBS LETTERS

Conventional progesterone receptors (PR) B and PRA are expressed in human spermatozoa and may be involved in the pathophysiology of varicocoele: a role for progesterone in metabolism

(2010) F. De Amicis et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Farnesoid X Receptor Activation Improves Erectile Function in Animal Models of Metabolic Syndrome and Diabetes

(2010) Linda Vignozzi et al.   Journal of Sexual Medicine

Alteration in male reproductive system in experimental cholestasis: Roles for opioids and nitric oxide overproduction

(2009) Samira Kiani et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Insulin and IR-β in pig spermatozoa: a role of the hormone in the acquisition of fertilizing ability

(2009) A. Carpino et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Abundant expression and purification of biologically active mitochondrial citrate carrier in baculovirus-infected insect cells

(2009) Marianna Madeo et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Farnesoid X Receptor, through the Binding with Steroidogenic Factor 1-responsive Element, Inhibits Aromatase Expression in Tumor Leydig Cells

(2009) Stefania Catalano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A new role of anandamide in human sperm: Focus on metabolism

(2009) Saveria Aquila et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Human male gamete endocrinology: 1alpha, 25-dihydroxyvitamin D3 (1,25(OH)2D3) regulates different aspects of human sperm biology and metabolism

(2009) Saveria Aquila et al.   Reproductive Biology and Endocrinology

Bile acids: Chemistry, physiology, and pathophysiology

(2009) Maria J Monte et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells

(2008) Jenny Kaeding et al.   BIOCHEMICAL JOURNAL

Immunolocalization of farnesoid X receptor (FXR) in mouse tissues using tissue microarray

(2007) Hiroyuki Higashiyama et al.   ACTA HISTOCHEMICA