Phloretin inhibits interleukin-1β-induced COX-2 and ICAM-1 expression through inhibition of MAPK, Akt, and NF-κB signaling in human lung epithelial cells

T-cell biology in immunotherapy

(2014) John W. Steinke et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Innate immunity in the lung regulates the development of asthma

(2014) Rosemarie H. DeKruyff et al.   IMMUNOLOGICAL REVIEWS

Leukocyte Production of Inflammatory Mediators Is Inhibited by the Antioxidants Phloretin, Silymarin, Hesperetin, and Resveratrol

(2014) Jezrom B. Fordham et al.   MEDIATORS OF INFLAMMATION

Immunomodulation of phloretin by impairing dendritic cell activation and function

(2014) Chi-Chen Lin et al.   Food & Function

Higher Frequency Ventilation Attenuates Lung Injury during High-frequency Oscillatory Ventilation in Sheep Models of Acute Respiratory Distress Syndrome

(2013) Songqiao Liu et al.   ANESTHESIOLOGY

Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL/6 mice

(2013) Jiali Guo et al.   ARCHIVES OF TOXICOLOGY

Curcumin ameliorates TNF-α-induced ICAM-1 expression and subsequent THP-1 adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells

(2013) Gi Soo Youn et al.   BMB Reports

The IκB kinase complex in NF-κB regulation and beyond

(2013) Michael Hinz et al.   EMBO REPORTS

Anti-inflammatory effect of sophoraflavanone G isolated from Sophora flavescens in lipopolysaccharide-stimulated mouse macrophages

(2013) Zih-Yi Wun et al.   FOOD AND CHEMICAL TOXICOLOGY

Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells

(2013) Paramasivan Poornima et al.   FOOD CHEMISTRY

Viral infection of the lung: Host response and sequelae

(2013) Jae-Kwang Yoo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Matrine attenuates allergic airway inflammation and eosinophil infiltration by suppressing eotaxin and Th2 cytokine production in asthmatic mice

(2013) Wen-Chung Huang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Therapeutic potential of anti-IL-1β IgY in guinea pigs with allergic asthma induced by ovalbumin

(2013) Hu Wei-xu et al.   MOLECULAR IMMUNOLOGY

Non-steroidal anti-inflammatory drug hypersensitivity in adults and the factors associated with asthma

(2013) Gul Karakaya et al.   RESPIRATORY MEDICINE

Echinocystic acid ameliorates lung inflammation in mice and alveolar macrophages by inhibiting the binding of LPS to TLR4 in NF-κB and MAPK pathways

(2012) Eun-Ha Joh et al.   BIOCHEMICAL PHARMACOLOGY

The role of interleukin-1 in allergy-related disorders

(2012) Karoline Krause et al.   Current Opinion in Allergy and Clinical Immunology

Evaluation of the anti-inflammatory effects of phloretin and phlorizin in lipopolysaccharide-stimulated mouse macrophages

(2012) Wei-Tien Chang et al.   FOOD CHEMISTRY

The effect of Phloretin on human γδ T cells killing colon cancer SW-1116 cells

(2012) Sheng-Ping Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Norcantharidin Facilitates LPS-Mediated Immune Responses by Up-Regulation of AKT/NF-κB Signaling in Macrophages

(2012) Qufei Zhao et al.   PLoS One

Role of IL-1  and the Nlrp3/caspase-1/IL-1  axis in cigarette smoke-induced pulmonary inflammation and COPD

(2011) N. S. Pauwels et al.   EUROPEAN RESPIRATORY JOURNAL

Inhibitory effects of casticin on migration of eosinophil and expression of chemokines and adhesion molecules in A549 lung epithelial cells via NF-κB inactivation

(2011) Duck-jae Koh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells

(2011) Yun Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

IL-1 and IL-23 Mediate Early IL-17A Production in Pulmonary Inflammation Leading to Late Fibrosis

(2011) Paméla Gasse et al.   PLoS One

Inflammasome-IL-1-Th17 response in allergic lung inflammation

(2011) A.-G. Besnard et al.   Journal of Molecular Cell Biology

A Mouse Model of Airway Disease: Oncostatin M-Induced Pulmonary Eosinophilia, Goblet Cell Hyperplasia, and Airway Hyperresponsiveness Are STAT6 Dependent, and Interstitial Pulmonary Fibrosis Is STAT6 Independent

(2010) D. K. Fritz et al.   JOURNAL OF IMMUNOLOGY

Mitogen-Activated Protein Kinase Phosphatase-1 Negatively Regulates the Expression of Interleukin-6, Interleukin-8, and Cyclooxygenase-2 in A549 Human Lung Epithelial Cells

(2010) T. Turpeinen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Phloridzin: Biosynthesis, distribution and physiological relevance in plants

(2010) Christian Gosch et al.   PHYTOCHEMISTRY

Regulation of Airway MUC5AC Expression by IL-1  and IL-17A; the NF- B Paradigm

(2009) T. Fujisawa et al.   JOURNAL OF IMMUNOLOGY

Isolation and characterization of a novel glycosyltransferase that converts phloretin to phlorizin, a potent antioxidant in apple

(2008) Hélène Jugdé et al.   FEBS Journal

In vitroandin vivostudy of phloretin-induced apoptosis in human liver cancer cells involving inhibition of type II glucose transporter

(2008) Chih-Hsiung Wu et al.   INTERNATIONAL JOURNAL OF CANCER

Apple polyphenol phloretin potentiates the anticancer actions of paclitaxel through induction of apoptosis in human hep G2 cells

(2008) Kuo-Ching Yang et al.   MOLECULAR CARCINOGENESIS