The roles of fascins in health and disease

How the Genetics of Deafness Illuminates Auditory Physiology

(2011) Guy P. Richardson et al.   Annual Review of Physiology

The Stepping Pattern of Myosin X Is Adapted for Processive Motility on Bundled Actin

(2010) Benjamin L. Ricca et al.   BIOPHYSICAL JOURNAL

miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer

(2010) T Chiyomaru et al.   BRITISH JOURNAL OF CANCER

The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion

(2010) Ang Li et al.   CURRENT BIOLOGY

Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines

(2010) Cristian M Ortiz et al.   Diagnostic Pathology

Tropomyosin isoform 3 promotes the formation of filopodia by regulating the recruitment of actin-binding proteins to actin filaments

(2010) Sarah J. Creed et al.   EXPERIMENTAL CELL RESEARCH

miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma

(2010) Masayuki Kano et al.   INTERNATIONAL JOURNAL OF CANCER

Unconventional Processive Mechanics of Non-muscle Myosin IIB

(2010) Melanie F. Norstrom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin Cross-link Assembly and Disassembly Mechanics for α-Actinin and Fascin

(2010) David S. Courson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro

(2010) Manuela Quintavalle et al.   JOURNAL OF CELL BIOLOGY

Structure, Evolutionary Conservation, and Conformational Dynamics of Homo sapiens Fascin-1, an F-actin Crosslinking Protein

(2010) Reza Sharifi Sedeh et al.   JOURNAL OF MOLECULAR BIOLOGY

The R109H Variant of Fascin-2, a Developmentally Regulated Actin Crosslinker in Hair-Cell Stereocilia, Underlies Early-Onset Hearing Loss of DBA/2J Mice

(2010) J.-B. Shin et al.   JOURNAL OF NEUROSCIENCE

Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma

(2010) María Ángeles Castilla et al.   JOURNAL OF PATHOLOGY

Migrastatin analogues target fascin to block tumour metastasis

(2010) Lin Chen et al.   NATURE

Electron tomography reveals unbranched networks of actin filaments in lamellipodia

(2010) Edit Urban et al.   NATURE CELL BIOLOGY

Self-Assembly of Filopodia-Like Structures on Supported Lipid Bilayers

(2010) Kwonmoo Lee et al.   SCIENCE

Fascin Regulates Prostate Cancer Cell Invasion and Is Associated with Metastasis and Biochemical Failure in Prostate Cancer

(2009) A. D. Darnel et al.   CLINICAL CANCER RESEARCH

Fascin is required for blood cell migration during Drosophila embryogenesis

(2009) J. Zanet et al.   DEVELOPMENT

Disruption of the cytoskeleton during Semaphorin 3A induced growth cone collapse correlates with differences in actin organization and associated binding proteins

(2009) Jacquelyn A. Brown et al.   Developmental Neurobiology

Galectin-3 Increases Gastric Cancer Cell Motility by Up-regulating Fascin-1 Expression

(2009) Seok–Jun Kim et al.   GASTROENTEROLOGY

Filopodia: Complex models for simple rods

(2009) Jan Faix et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Effects of small interfering RNAs targeting Fascin on gene expression in oral cancer cells

(2009) Su-Feng Chen et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Comparative Proteomic Analysis of Mouse Melanoma Cell Line B16, a Metastatic Descendant B16F10, and B16 Overexpressing the Metastasis-Associated Tyrosine Phosphatase PRL-3

(2009) Sang Hee Kim et al.   ONCOLOGY RESEARCH

Fascin-1 Promoter Activity Is Regulated by CREB and the Aryl Hydrocarbon Receptor in Human Carcinoma Cells

(2009) Yosuke Hashimoto et al.   PLoS One

Analysis of proteomic changes associated with sperm capacitation through the combined use of IPG-strip pre-fractionation followed by RP chromatography LC-MS/MS analysis

(2009) Mark A. Baker et al.   PROTEOMICS

Rab35 Controls Actin Bundling by Recruiting Fascin as an Effector Protein

(2009) J. Zhang et al.   SCIENCE

Fascin1 is dispensable for mouse development but is favorable for neonatal survival

(2009) Yoshihiko Yamakita et al.   CELL MOTILITY AND THE CYTOSKELETON

Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella

(2008) Maria Nemethova et al.   JOURNAL OF CELL BIOLOGY

Rac regulates the interaction of fascin with protein kinase C in cell migration

(2008) M. Parsons et al.   JOURNAL OF CELL SCIENCE

The Filamentous Actin Cross-Linking/Bundling Activity of Mammalian Formins

(2008) Osigwe Esue et al.   JOURNAL OF MOLECULAR BIOLOGY

Proteomic analysis of stargazer mutant mouse neuronal proteins involved in absence seizure

(2008) Myung-Jeom Ryu et al.   JOURNAL OF NEUROCHEMISTRY

Ubiquitin Proteasome-Mediated Synaptic Reorganization: A Novel Mechanism Underlying Rapid Ischemic Tolerance

(2008) R. Meller et al.   JOURNAL OF NEUROSCIENCE

Proper Cellular Reorganization during Drosophila Spermatid Individualization Depends on Actin Structures Composed of Two Domains, Bundles and Meshwork, That Are Differentially Regulated and Have Different Functions

(2008) Tatsuhiko Noguchi et al.   MOLECULAR BIOLOGY OF THE CELL

Filopodia: molecular architecture and cellular functions

(2008) Pieta K. Mattila et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Arp2/3 Branched Actin Network Mediates Filopodia-Like Bundles Formation In Vitro

(2008) Yaron Ideses et al.   PLoS One

mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization

(2008) B. Gan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Fascin in the Migration and Invasiveness of Malignant Glioma Cells

(2008) Jeong Hyun Hwang et al.   NEOPLASIA

A Cytoskeletal Demolition Worker: Myosin II Acts as an Actin Depolymerization Agent

(2007) Lior Haviv et al.   JOURNAL OF MOLECULAR BIOLOGY