Mesenchymal stem cells, autoimmunity and rheumatoid arthritis

The influence of bone marrow- and synovium-derived mesenchymal stromal cells from osteoarthritis patients on regulatory T cells in co-culture

(2013) S. Hagmann et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Mesenchymal stem cells in joint disease and repair

(2013) Frank Barry et al.   Nature Reviews Rheumatology

Human Umbilical Cord Mesenchymal Stem Cell Therapy for Patients with Active Rheumatoid Arthritis: Safety and Efficacy

(2013) Liming Wang et al.   STEM CELLS AND DEVELOPMENT

Bone marrow-derived and synovium-derived mesenchymal cells promote Th17 cell expansion and activation through caspase 1 activation: Contribution to the chronicity of rheumatoid arthritis

(2012) Assia Eljaafari et al.   ARTHRITIS AND RHEUMATISM

IL-15 Expression on RA Synovial Fibroblasts Promotes B Cell Survival

(2012) Marta Benito-Miguel et al.   PLoS One

Genetic mismatch affects the immunosuppressive properties of mesenchymal stem cells in vitro and their ability to influence the course of collagen-induced arthritis

(2012) Catherine Sullivan et al.   ARTHRITIS RESEARCH & THERAPY

A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells

(2011) M. Bombardieri et al.   ANNALS OF THE RHEUMATIC DISEASES

Allogeneic mesenchymal stem cells transplantation in patients with refractory RA

(2011) Jun Liang et al.   CLINICAL RHEUMATOLOGY

Mesenchymal stem cells promote the sustained expression of CD69 on activated T lymphocytes: roles of canonical and non-canonical NF-κB signalling

(2011) Felipe Saldanha-Araujo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis

(2011) Ichiro Sekiya et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mesenchymal stromal cell ‘licensing’: a multistep process

(2011) M Krampera   LEUKEMIA

Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study

(2010) J. Liang et al.   ANNALS OF THE RHEUMATIC DISEASES

Defective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosus

(2010) Y. Nie et al.   LUPUS

A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype

(2010) Ruth S. Waterman et al.   PLoS One

Rheumatoid arthritis progression mediated by activated synovial fibroblasts

(2010) Elena Neumann et al.   TRENDS IN MOLECULAR MEDICINE

Flow cytometric characterization of freshly isolated and culture expanded human synovial cell populations in patients with chronic arthritis

(2010) Kristel B Van Landuyt et al.   ARTHRITIS RESEARCH & THERAPY

Mesenchymal stem cells in rheumatoid synovium: enumeration and functional assessment in relation to synovial inflammation level

(2009) E Jones et al.   ANNALS OF THE RHEUMATIC DISEASES

Cell death in rheumatoid arthritis

(2009) Adelheid Korb et al.   APOPTOSIS

A critical role of Cyr61 in interleukin-17–dependent proliferation of fibroblast-like synoviocytes in rheumatoid arthritis

(2009) Qiuyu Zhang et al.   ARTHRITIS AND RHEUMATISM

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and Activates Macrophages Primarily via TLR2 Signaling

(2009) Q.-Q. Huang et al.   JOURNAL OF IMMUNOLOGY

Cytokine Modulation of TLR Expression and Activation in Mesenchymal Stromal Cells Leads to a Proinflammatory Phenotype

(2009) R. Romieu-Mourez et al.   JOURNAL OF IMMUNOLOGY

Autologous mesenchymal stem cell treatment increased T regulatory cells with no effect on disease activity in two systemic lupus erythematosus patients

(2009) F. Carrion et al.   LUPUS

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R

(2009) Christiane A. Opitz et al.   STEM CELLS

Synovium-Derived Mesenchymal Stem Cells: A New Cell Source for Musculoskeletal Regeneration

(2009) Jiabing Fan et al.   TISSUE ENGINEERING PART B-REVIEWS

The role of Toll-like receptors in rheumatoid arthritis

(2009) Qi-Quan Huang et al.   Current Rheumatology Reports

Analysis of the chondrogenic potential of human synovial stem cells according to harvest site and culture parameters in knees with medial compartment osteoarthritis

(2008) Tsuyoshi Nagase et al.   ARTHRITIS AND RHEUMATISM

Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: Toll-like receptor expression in early and longstanding arthritis

(2008) Caroline Ospelt et al.   ARTHRITIS AND RHEUMATISM

Synovial fluid mesenchymal stem cells in health and early osteoarthritis: Detection and functional evaluation at the single-cell level

(2008) Elena A. Jones et al.   ARTHRITIS AND RHEUMATISM

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

(2008) David Polchert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation

(2008) Tatyana B. Prigozhina et al.   EXPERIMENTAL HEMATOLOGY

Mesenchymal cells recruit and regulate T regulatory cells

(2008) M DIIANNI   EXPERIMENTAL HEMATOLOGY

Mesenchymal stem cells: the fibroblasts' new clothes?

(2008) M. A. Haniffa et al.   HAEMATOLOGICA

Clonal chondroprogenitors maintain telomerase activity and Sox9 expression during extended monolayer culture and retain chondrogenic potential

(2008) I.M. Khan et al.   OSTEOARTHRITIS AND CARTILAGE

MSC Frequency Correlates with Blood Vessel Density in Equine Adipose Tissue

(2008) Lindolfo da Silva Meirelles et al.   TISSUE ENGINEERING PART A

Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+Regulatory T Cells

(2007) Zohair Selmani et al.   STEM CELLS