Reduction of excessive alcohol drinking by a novel GABAB receptor positive allosteric modulator ADX71441 in mice

Adherence Monitoring in Naltrexone Pharmacotherapy Trials: A Systematic Review*

(2015) Robert Swift et al.   Journal of Studies on Alcohol and Drugs

Comparison of the effects of the GABAB receptor positive modulator BHF177 and the GABAB receptor agonist baclofen on anxiety-like behavior, learning, and memory in mice

(2013) Xia Li et al.   NEUROPHARMACOLOGY

Escalation of intake under intermittent ethanol access in diverse mouse genotypes

(2012) Alan M. Rosenwasser et al.   ADDICTION BIOLOGY

Reduction of alcohol intake by the positive allosteric modulator of the GABAB receptor, rac-BHFF, in alcohol-preferring rats

(2012) Barbara Loi et al.   ALCOHOL

Intermittent Availability of Ethanol Does Not Always Lead to Elevated Drinking in Mice

(2012) John C. Crabbe et al.   ALCOHOL AND ALCOHOLISM

Comparison of the Effect of the GABABReceptor Agonist, Baclofen, and the Positive Allosteric Modulator of the GABABReceptor, GS39783, on Alcohol Self-Administration in 3 Different Lines of Alcohol-Preferring Rats

(2012) Paola Maccioni et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

GABAB receptor agonist only reduces ethanol drinking in light-drinking mice

(2012) Gustavo Roberto Villas Boas et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A transcriptional study in mice with different ethanol-drinking profiles: Possible involvement of the GABAB receptor

(2012) Andrea Frozino Ribeiro et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A human laboratory pilot study with baclofen in alcoholic individuals

(2012) Lorenzo Leggio et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Organization of GABAergic Synaptic Circuits in the Rat Ventral Tegmental Area

(2012) Alessandro Ciccarelli et al.   PLoS One

Alcohol in excess: CRF1 receptors in the rat and mouse VTA and DRN

(2012) Lara S. Hwa et al.   PSYCHOPHARMACOLOGY

Operant, oral alcoholic beer self-administration by C57BL/6J mice: effect of BHF177, a positive allosteric modulator of GABAB receptors

(2012) Alessandro Orrù et al.   PSYCHOPHARMACOLOGY

Baclofen promotes alcohol abstinence in alcohol dependent cirrhotic patients with hepatitis C virus (HCV) infection

(2011) L. Leggio et al.   ADDICTIVE BEHAVIORS

Intermittent (Every-Other-Day) Drinking Induces Rapid Escalation of Ethanol Intake and Preference in Adolescent and Adult C57BL/6J Mice

(2011) Roberto I. Melendez   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Persistent Escalation of Alcohol Drinking in C57BL/6J Mice With Intermittent Access to 20% Ethanol

(2011) Lara S. Hwa et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Pharmacogenetic approaches to the treatment of alcohol addiction

(2011) Markus Heilig et al.   NATURE REVIEWS NEUROSCIENCE

In vitro and in vivo characterization of the novel GABAB receptor positive allosteric modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE)

(2011) Elisabetta Perdona’ et al.   NEUROPHARMACOLOGY

Allosteric Modulation of Family C G-Protein-Coupled Receptors: from Molecular Insights to Therapeutic Perspectives

(2011) S. Urwyler   PHARMACOLOGICAL REVIEWS

Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinking

(2010) Michelle A. Tanchuck et al.   ALCOHOL

Safety and Efficacy of Baclofen in the Treatment of Alcohol-Dependent Patients

(2010) Giovanni Addolorato et al.   CURRENT PHARMACEUTICAL DESIGN

The positive allosteric modulator of the GABAB receptor, rac-BHFF, suppresses alcohol self-administration

(2010) Paola Maccioni et al.   DRUG AND ALCOHOL DEPENDENCE

Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats

(2010) Styliani Vlachou et al.   PSYCHOPHARMACOLOGY

Reduction of Alcohol’s Reinforcing and Motivational Properties by the Positive Allosteric Modulator of the GABABReceptor, BHF177, in Alcohol-Preferring Rats

(2009) Paola Maccioni et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Site-specific microinjection of baclofen into the anterior ventral tegmental area reduces binge-like ethanol intake in male C57BL/6J mice.

(2009) Eileen M. Moore et al.   BEHAVIORAL NEUROSCIENCE

Social cost of heavy drinking and alcohol dependence in high-income countries

(2009) Satya Mohapatra et al.   International Journal of Public Health

Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells

(2009) Natalia Omelchenko et al.   SYNAPSE

Voluntary ethanol consumption in 22 inbred mouse strains

(2008) Naomi Yoneyama et al.   ALCOHOL

Specific Reduction of Alcohol’s Motivational Properties by the Positive Allosteric Modulator of the GABABReceptor, GS39783-Comparison With the Effect of the GABABReceptor Direct Agonist, Baclofen

(2008) Paola Maccioni et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Acute Interaction of Baclofen in Combination With Alcohol in Heavy Social Drinkers

(2008) Suzette M. Evans et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Baclofen attenuates cue-induced reinstatement of alcohol-seeking behavior in Sardinian alcohol-preferring (sP) rats

(2008) Paola Maccioni et al.   DRUG AND ALCOHOL DEPENDENCE

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

(2008) P. Jeffrey Conn et al.   NATURE REVIEWS DRUG DISCOVERY

Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents

(2008) Laura H. Jacobson et al.   NEUROPHARMACOLOGY