Exploring shared genetic bases and causal relationships of schizophrenia and bipolar disorder with 28 cardiovascular and metabolic traits

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

(2017) Fernando Pires Hartwig et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Meta-analysis of glucose tolerance, insulin, and insulin resistance in antipsychotic-naïve patients with nonaffective psychosis

(2017) Anne Marie Greenhalgh et al.   SCHIZOPHRENIA RESEARCH

Impaired Glucose Homeostasis in First-Episode Schizophrenia

(2017) Toby Pillinger et al.   JAMA Psychiatry

Transethnic Genetic-Correlation Estimates from Summary Statistics

(2016) Brielin C. Brown et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Bias due to participant overlap in two-sample Mendelian randomization

(2016) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

(2016) Liping Hou et al.   HUMAN MOLECULAR GENETICS

Are leptin levels increased among people with schizophrenia versus controls? A systematic review and comparative meta-analysis

(2016) Brendon Stubbs et al.   PSYCHONEUROENDOCRINOLOGY

Body mass index and psychiatric disorders: a Mendelian randomization study

(2016) Fernando Pires Hartwig et al.   Scientific Reports

A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a Trait

(2015) Luigi Palla et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

Plasma adiponectin levels in schizophrenia and role of second-generation antipsychotics: A meta-analysis

(2015) Francesco Bartoli et al.   PSYCHONEUROENDOCRINOLOGY

PRSice: Polygenic Risk Score software

(2014) Jack Euesden et al.   BIOINFORMATICS

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Genetic Relationships Between Schizophrenia, Bipolar Disorder, and Schizoaffective Disorder

(2014) A. G. Cardno et al.   SCHIZOPHRENIA BULLETIN

A randomized placebo-controlled pilot study of pravastatin as an adjunctive therapy in schizophrenia patients: Effect on inflammation, psychopathology, cognition and lipid metabolism

(2014) Brenda Vincenzi et al.   SCHIZOPHRENIA RESEARCH

Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors

(2013) Ole A. Andreassen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Metabolic Syndrome and Metabolic Abnormalities in Bipolar Disorder: A Meta-Analysis of Prevalence Rates and Moderators

(2013) Davy Vancampfort et al.   AMERICAN JOURNAL OF PSYCHIATRY

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

The Epidermal Growth Factor Receptor and Its Ligands in Cardiovascular Disease

(2013) Nader Makki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates

(2013) David M. Evans et al.   PLoS Genetics

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

(2012) Zari Dastani et al.   PLoS Genetics

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Life expectancy among persons with schizophrenia or bipolar affective disorder

(2011) Thomas Munk Laursen   SCHIZOPHRENIA RESEARCH

Metabolic syndrome with the atypical antipsychotics

(2011) Pornpoj Pramyothin et al.   Current Opinion in Endocrinology Diabetes and Obesity

Low prevalence of obesity and metabolic syndrome in never-treated chronic schizophrenia

(2010) Ramachandran Padmavati et al.   SCHIZOPHRENIA RESEARCH

Strengthening causal inference in cardiovascular epidemiology through Mendelian randomization

(2008) George Davey Smith et al.   ANNALS OF MEDICINE

Leptin and Cardiovascular Disease

(2008) Kwang Kon Koh et al.   CIRCULATION

Prevalence and correlates of overweight in drug-naïve patients with bipolar disorder

(2008) Giuseppe Maina et al.   JOURNAL OF AFFECTIVE DISORDERS

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

(2008) Chiara Sabatti et al.   NATURE GENETICS

Are metabolic indices different between drug-naïve first-episode psychosis patients and healthy controls?

(2008) S SENGUPTA et al.   SCHIZOPHRENIA RESEARCH

‘Mendelian randomization’ equals instrumental variable analysis with genetic instruments

(2008) George L. Wehby et al.   STATISTICS IN MEDICINE