Beyond antibodies: New affinity reagents to unlock the proteome

Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

(2013) Francesco S. Loffredo et al.   CELL

Detection of Clostridium difficile toxins A, B and binary toxin with slow off-rate modified aptamers

(2013) Urs A. Ochsner et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Finding the right antibody for the job

(2013) Vivien Marx   NATURE METHODS

Measurement of Cetuximab and Panitumumab-Unbound Serum EGFR Extracellular Domain Using an Assay Based on Slow Off-Rate Modified Aptamer (SOMAmer) Reagents

(2013) Noh Jin Park et al.   PLoS One

Antigen–antibody interface properties: Composition, residue interactions, and features of 53 non-redundant structures

(2012) Thiruvarangan Ramaraj et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The Long Journey of Cancer Biomarkers from the Bench to the Clinic

(2012) M. P. Pavlou et al.   CLINICAL CHEMISTRY

Life's Simple Measures: Unlocking the Proteome

(2012) Edward Brody et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein Signature of Lung Cancer Tissues

(2012) Michael R. Mehan et al.   PLoS One

Early Detection of Malignant Pleural Mesothelioma in Asbestos-Exposed Individuals with a Noninvasive Proteomics-Based Surveillance Tool

(2012) Rachel M. Ostroff et al.   PLoS One

Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets

(2012) D. R. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative and sensitive protein detection strategies based on aptamers

(2012) Yoshihito Yoshida et al.   Proteomics Clinical Applications

Age-Dependent Changes in the Cerebrospinal Fluid Proteome by Slow Off-Rate Modified Aptamer Array

(2011) Geoffrey S. Baird et al.   AMERICAN JOURNAL OF PATHOLOGY

Beyond natural antibodies: the power of in vitro display technologies

(2011) Andrew R M Bradbury et al.   NATURE BIOTECHNOLOGY

Unlocking Biomarker Discovery: Large Scale Application of Aptamer Proteomic Technology for Early Detection of Lung Cancer

(2011) Rachel M. Ostroff et al.   PLoS One

Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

(2011) Larry Gold et al.   PLoS One

From SOMAmer-Based Biomarker Discovery to Diagnostic and Clinical Applications: A SOMAmer-Based, Streamlined Multiplex Proteomic Assay

(2011) Stephan Kraemer et al.   PLoS One

Probing the Limits of Aptamer Affinity with a Microfluidic SELEX Platform

(2011) Kareem M. Ahmad et al.   PLoS One

Expanding the Chemistry of DNA for in Vitro Selection

(2010) Jonathan D. Vaught et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aptamers and the RNA World, Past and Present

(2010) L. Gold et al.   Cold Spring Harbor Perspectives in Biology

Antibody-Based Protein Multiplex Platforms: Technical and Operational Challenges

(2009) A. A. Ellington et al.   CLINICAL CHEMISTRY

Aptamers as inhibitors of target proteins

(2009) S Missailidis et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

The current status of IGF-I assays – A 2009 update

(2009) Jan Frystyk et al.   GROWTH HORMONE & IGF RESEARCH

The stability of the circulating human proteome to variations in sample collection and handling procedures measured with an aptamer-based proteomics array

(2009) Rachel Ostroff et al.   Journal of Proteomics

The interface between biomarker discovery and clinical validation: The tar pit of the protein biomarker pipeline

(2008) Amanda G. Paulovich et al.   Proteomics Clinical Applications