History of protein-protein interactions: From egg-white to complex networks

Erratum: Interfacial inhibitors: targeting macromolecular complexes

(2012) Yves Pommier et al.   NATURE REVIEWS DRUG DISCOVERY

Interactome mapping for analysis of complex phenotypes: Insights from benchmarking binary interaction assays

(2012) Pascal Braun   PROTEOMICS

New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size

(2011) Laure Sambourg et al.   BMC BIOINFORMATICS

When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases

(2011) Vincent Navratil et al.   BMC Systems Biology

Analysis of the Human Endogenous Coregulator Complexome

(2011) Anna Malovannaya et al.   CELL

Interactome Networks and Human Disease

(2011) Marc Vidal et al.   CELL

Using yeast as a model to study membrane proteins

(2011) Julia Petschnigg et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Insight into Bacterial Virulence Mechanisms against Host Immune Response via the Yersinia pestis-Human Protein-Protein Interaction Network

(2011) Huiying Yang et al.   INFECTION AND IMMUNITY

A roadmap to generate renewable protein binders to the human proteome

(2011) Karen Colwill et al.   NATURE METHODS

A public genome-scale lentiviral expression library of human ORFs

(2011) Xiaoping Yang et al.   NATURE METHODS

The network takeover

(2011) Albert-László Barabási   Nature Physics

A Network-Based Approach to Prioritize Results from Genome-Wide Association Studies

(2011) Nirmala Akula et al.   PLoS One

Evidence for Network Evolution in an Arabidopsis Interactome Map

(2011) et al.   SCIENCE

Independently Evolved Virulence Effectors Converge onto Hubs in a Plant Immune System Network

(2011) M. S. Mukhtar et al.   SCIENCE

Virus–host interactomes and global models of virus-infected cells

(2011) Caroline C. Friedel et al.   TRENDS IN MICROBIOLOGY

Protein Complexes are Central in the Yeast Genetic Landscape

(2011) Magali Michaut et al.   PLoS Computational Biology

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

(2011) Elizabeth J. Rossin et al.   PLoS Genetics

A Decade of Systems Biology

(2010) Han-Yu Chuang et al.   Annual Review of Cell and Developmental Biology

Large-scale protein interactome mapping: strategies and opportunities

(2010) Sam Lievens et al.   Expert Review of Proteomics

Interactome mapping suggests new mechanistic details underlying Alzheimer's disease

(2010) M. Soler-Lopez et al.   GENOME RESEARCH

Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions

(2010) Nina C. Hubner et al.   JOURNAL OF CELL BIOLOGY

Modeling Contaminants in AP-MS/MS Experiments

(2010) Mathieu Lavallée-Adam et al.   JOURNAL OF PROTEOME RESEARCH

Cell mechanics and the cytoskeleton

(2010) Daniel A. Fletcher et al.   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

ProHits: integrated software for mass spectrometry–based interaction proteomics

(2010) Guomin Liu et al.   NATURE BIOTECHNOLOGY

SAINT: probabilistic scoring of affinity purification–mass spectrometry data

(2010) Hyungwon Choi et al.   NATURE METHODS

Exhaustive benchmarking of the yeast two-hybrid system

(2010) Yu-Chi Chen et al.   NATURE METHODS

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

A Rice gid1 Suppressor Mutant Reveals That Gibberellin Is Not Always Required for Interaction between Its Receptor, GID1, and DELLA Proteins

(2010) Y. Yamamoto et al.   PLANT CELL

A Global Protein Kinase and Phosphatase Interaction Network in Yeast

(2010) A. Breitkreutz et al.   SCIENCE

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

A membrane protein / signaling protein interaction network for Arabidopsis version AMPv2

(2010) Sylvie Lalonde   Frontiers in Physiology

Phosphorylase and the origin of reversible protein phosphorylation

(2009) Edmond H. Fischer   BIOLOGICAL CHEMISTRY

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

A network medicine approach to human disease

(2009) Andreas Zanzoni et al.   FEBS LETTERS

Edgetic perturbation models of human inherited disorders

(2009) Quan Zhong et al.   Molecular Systems Biology

Dynamic modularity in protein interaction networks predicts breast cancer outcome

(2009) Ian W Taylor et al.   NATURE BIOTECHNOLOGY

'Edgetic' perturbation of a C. elegans BCL2 ortholog

(2009) Matija Dreze et al.   NATURE METHODS

Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes

(2009) Gregory Hannum et al.   PLoS Genetics

Monoclonal Antibodies as Innovative Therapeutics

(2008) Janice Reichert   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

A Large Scale Analysis of Protein-Protein Interactions in the Nitrogen-fixing Bacterium Mesorhizobium loti

(2008) Y. Shimoda et al.   DNA RESEARCH

Small-molecule inhibitors of the p53-HDM2 interaction for the treatment of cancer

(2008) Sharmila Patel et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

From E-MAPs to module maps: dissecting quantitative genetic interactions using physical interactions

(2008) Igor Ulitsky et al.   Molecular Systems Biology

Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network

(2008) Nicolas Simonis et al.   NATURE METHODS

An empirical framework for binary interactome mapping

(2008) Kavitha Venkatesan et al.   NATURE METHODS

An experimentally derived confidence score for binary protein-protein interactions

(2008) Pascal Braun et al.   NATURE METHODS

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH

A Biomedically Enriched Collection of 7000 Human ORF Clones

(2008) Andreas Rolfs et al.   PLoS One

Estimating the size of the human interactome

(2008) M. P. H. Stumpf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

(2008) M. E. Sardiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

(2008) H. Yu et al.   SCIENCE

An in Vivo Map of the Yeast Protein Interactome

(2008) K. Tarassov et al.   SCIENCE

Functional Maps of Protein Complexes from Quantitative Genetic Interaction Data

(2008) Sourav Bandyopadhyay et al.   PLoS Computational Biology

The receptor concept: pharmacology's big idea

(2006) H P Rang   BRITISH JOURNAL OF PHARMACOLOGY

Heterotrimeric G-proteins: a short history

(2006) Graeme Milligan et al.   BRITISH JOURNAL OF PHARMACOLOGY