Proteomic analysis identifies differentially expressed proteins after HDAC vorinostat and EGFR inhibitor gefitinib treatments in Hep-2 cancer cells

Activation of the Unfolded Protein Response Contributes toward the Antitumor Activity of Vorinostat

(2015) Soumen Kahali et al.   NEOPLASIA

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8

(2010) Alex D Chacko et al.   BMC CANCER

Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or Raltitrexed

(2010) Elena Di Gennaro et al.   CANCER BIOLOGY & THERAPY

Heterogeneous Nuclear Ribonucleoprotein H Blocks MST2-Mediated Apoptosis in Cancer Cells by Regulating a-raf Transcription

(2010) J. Rauch et al.   CANCER RESEARCH

Negative Regulation of p53 by the Long Isoform of ErbB3 Binding Protein Ebp1 in Brain Tumors

(2010) C. K. Kim et al.   CANCER RESEARCH

New Strategies in Head and Neck Cancer: Understanding Resistance to Epidermal Growth Factor Receptor Inhibitors

(2010) L. F. Chen et al.   CLINICAL CANCER RESEARCH

Characterization of side population cells from laryngeal cancer cell lines

(2010) Guanglun Wan et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Histone Deacetylase Inhibitors Activate NF-κB in Human Leukemia Cells through an ATM/NEMO-related Pathway

(2010) Roberto R. Rosato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT

(2010) Francesca Bruzzese et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Integrative Analysis of Proteomic Signatures, Mutations, and Drug Responsiveness in the NCI 60 Cancer Cell Line Set

(2010) E. S. Park et al.   MOLECULAR CANCER THERAPEUTICS

Treatment with Panobinostat Induces Glucose-Regulated Protein 78 Acetylation and Endoplasmic Reticulum Stress in Breast Cancer Cells

(2010) Rekha Rao et al.   MOLECULAR CANCER THERAPEUTICS

Understanding resistance to EGFR inhibitors—impact on future treatment strategies

(2010) Deric L. Wheeler et al.   Nature Reviews Clinical Oncology

Metabolism and proliferation share common regulatory pathways in cancer cells

(2010) V Fritz et al.   ONCOGENE

Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

(2010) Guy Lahat et al.   PLoS One

Epithelial-to-mesenchymal transition and c-myc expression are the determinants of cetuximab-induced enhancement of squamous cell carcinoma radioresponse

(2010) Ira Skvortsova et al.   RADIOTHERAPY AND ONCOLOGY

Increased expression of enolase α in human breast cancer confers tamoxifen resistance in human breast cancer cells

(2009) Shih-Hsin Tu et al.   BREAST CANCER RESEARCH AND TREATMENT

Development of vorinostat: Current applications and future perspectives for cancer therapy

(2009) Victoria M. Richon et al.   CANCER LETTERS

HDACi – Targets beyond chromatin

(2009) Marc Buchwald et al.   CANCER LETTERS

Complex relationship between TCTP, microtubules and actin microfilaments regulates cell shape in normal and cancer cells

(2009) Franck Bazile et al.   CARCINOGENESIS

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

(2009) Ji Luo et al.   CELL

Delta-Crystallin Enhancer Binding Factor 1 Controls the Epithelial to Mesenchymal Transition Phenotype and Resistance to the Epidermal Growth Factor Receptor Inhibitor Erlotinib in Human Head and Neck Squamous Cell Carcinoma Lines

(2009) Y. Haddad et al.   CLINICAL CANCER RESEARCH

Identification of Biomarkers in Human Head and Neck Tumor Cell Lines That Predict ForIn VitroSensitivity to Gefitinib

(2009) D. Mark Hickinson et al.   CTS-Clinical and Translational Science

An integrated humoral and cellular response is elicited in pancreatic cancer by α-enolase, a novel pancreatic ductal adenocarcinoma-associated antigen

(2009) Paola Cappello et al.   INTERNATIONAL JOURNAL OF CANCER

Histone Deacetylase Inhibitors in Cancer Therapy

(2009) Andrew A. Lane et al.   JOURNAL OF CLINICAL ONCOLOGY

Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis

(2009) P. Baumeister et al.   MOLECULAR CANCER THERAPEUTICS

Synergistic antitumor effect between vorinostat and topotecan in small cell lung cancer cells is mediated by generation of reactive oxygen species and DNA damage-induced apoptosis

(2009) F. Bruzzese et al.   MOLECULAR CANCER THERAPEUTICS

Neuroendocrine differentiation of LNCaP cells suggests: VDAC in the cell membrane is involved in the extrinsic apoptotic pathway

(2009) Friedrich P. Thinnes   MOLECULAR GENETICS AND METABOLISM

p21CIP1attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo

(2009) Manran Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cells

(2008) Alberto Milli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Inhibition of heregulin mediated MCF-7 breast cancer cell growth by the ErbB3 binding protein EBP1

(2008) Yuexing Zhang et al.   CANCER LETTERS

TCTP protects from apoptotic cell death by antagonizing bax function

(2008) L Susini et al.   CELL DEATH AND DIFFERENTIATION

Retinoic acid-mediated down-regulation of ENO1/MBP-1 gene products caused decreased invasiveness of the follicular thyroid carcinoma cell lines

(2008) Bogusz Trojanowicz et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Human BRE1 Is an E3 Ubiquitin Ligase for Ebp1 Tumor Suppressor

(2008) Zhixue Liu et al.   MOLECULAR BIOLOGY OF THE CELL

EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistance

(2008) Yuexing Zhang et al.   MOLECULAR CANCER THERAPEUTICS

A positive role for Myc in TGFβ-induced Snail transcription and epithelial-to-mesenchymal transition

(2008) A P Smith et al.   ONCOGENE

Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death

(2008) N Tajeddine et al.   ONCOGENE

HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation

(2008) R. B. Parmigiani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial–mesenchymal transition and the invasive potential of tumors

(2008) Nancy Gavert et al.   TRENDS IN MOLECULAR MEDICINE