Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects
Authors
Keywords
-
Journal
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Volume 83, Issue 1, Pages 25-36
Publisher
Wiley
Online
2014-05-16
DOI
10.1002/prot.24605
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CDC25A targeting by miR-483-3p decreases CCND–CDK4/6 assembly and contributes to cell cycle arrest
- (2013) T Bertero et al. CELL DEATH AND DIFFERENTIATION
- Mineralocorticoid Receptor Phosphorylation Regulates Ligand Binding and Renal Response to Volume Depletion and Hyperkalemia
- (2013) Shigeru Shibata et al. Cell Metabolism
- Androgen Receptor Phosphorylation at Serine 308 and Serine 791 Predicts Enhanced Survival in Castrate Resistant Prostate Cancer Patients
- (2013) Pamela McCall et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Phosphorylation of the Activation Loop Tyrosine 823 in c-Kit Is Crucial for Cell Survival and Proliferation
- (2013) Shruti Agarwal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Precisely Ordered Phosphorylation Reactions in the p38 Mitogen-activated Protein (MAP) Kinase Cascade
- (2013) John M. Humphreys et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oncogene PKCε controls INrf2–Nrf2 interaction in normal and cancer cells through phosphorylation of INrf2
- (2013) Suryakant K. Niture et al. JOURNAL OF CELL SCIENCE
- Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A)
- (2013) Wojciech Kaczmarski et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
- (2013) Georgia Hatzivassiliou et al. NATURE
- Epidermal Growth Factor Receptor Protects Proliferating Cell Nuclear Antigen from Cullin 4A Protein-mediated Proteolysis
- (2012) Yuan-Hung Lo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Small Molecule Proliferating Cell Nuclear Antigen (PCNA) Inhibitor That Disrupts Interactions with PIP-box Proteins and Inhibits DNA Replication
- (2012) Chandanamali Punchihewa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The good, the bad and the twisted: a survey of ligand geometry in protein crystal structures
- (2012) John Liebeschuetz et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- An Unusual Two-Step Control of CPEB Destruction by Pin1
- (2012) M. Nechama et al. MOLECULAR AND CELLULAR BIOLOGY
- Estrogen Receptor α/β–cofactor motif interactions; interplay of tyrosine 537/488 phosphorylation and LXXLL motifs
- (2012) Hoang D. Nguyen et al. Molecular BioSystems
- Thr90phosphorylation of Hsp90α by protein kinase A regulates its chaperone machinery
- (2011) Xiaofeng Wang et al. BIOCHEMICAL JOURNAL
- Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation
- (2011) L. Jirmanova et al. BLOOD
- A New Highly Efficient Substrate-trapping Mutant of Protein Tyrosine Phosphatase 1B (PTP1B) Reveals Full Autoactivation of the Insulin Receptor Precursor
- (2011) Samira Boubekeur et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD+ Redox Homeostasis in Cancer Cells
- (2011) J. Fan et al. MOLECULAR AND CELLULAR BIOLOGY
- Targeting Tyrosine Phosphorylation of PCNA Inhibits Prostate Cancer Growth
- (2011) H. Zhao et al. MOLECULAR CANCER THERAPEUTICS
- Death-Associated Protein Kinase 1 Phosphorylates Pin1 and Inhibits Its Prolyl Isomerase Activity and Cellular Function
- (2011) Tae Ho Lee et al. MOLECULAR CELL
- Coronin 2A mediates actin-dependent de-repression of inflammatory response genes
- (2011) Wendy Huang et al. NATURE
- PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse
- (2011) P. V. Hornbeck et al. NUCLEIC ACIDS RESEARCH
- Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation
- (2011) T Miyake et al. ONCOGENE
- Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase
- (2010) Anthony J. Sampognaro et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and Crystal Structure of a Phosphorylated Estrogen Receptor Ligand Binding Domain
- (2010) Sabine Möcklinghoff et al. CHEMBIOCHEM
- Design of Potent IGF1-R Inhibitors Related to Bis-azaindoles
- (2010) Conception Nemecek et al. Chemical Biology & Drug Design
- Activity of Retinoic Acid Receptor-alpha Is Directly Regulated at Its Protein Kinase A Sites in Response to Follicle-Stimulating Hormone Signaling
- (2010) Nadine C. Santos et al. ENDOCRINOLOGY
- Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance
- (2010) J. P. DiNitto et al. JOURNAL OF BIOCHEMISTRY
- Probing the Active Site of the DeoxynucleotideN-Hydrolase Rcl Encoded by the Rat Gene c6orf108
- (2010) Christelle Dupouy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformation Changes, N-terminal Involvement, and cGMP Signal Relay in the Phosphodiesterase-5 GAF Domain
- (2010) Huanchen Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutual Regulation of Src Family Kinases and the Neurotrophin Receptor TrkB
- (2010) Yang Z. Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Constitutive activation of the mitogen-activated protein kinase pathway impairs vitamin D signaling in human prostate epithelial cells
- (2010) Zhentao Zhang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Negative Regulation of Vps34 by Cdk Mediated Phosphorylation
- (2010) Tsuyoshi Furuya et al. MOLECULAR CELL
- Phospho.ELM: a database of phosphorylation sites--update 2011
- (2010) H. Dinkel et al. NUCLEIC ACIDS RESEARCH
- PHOSIDA 2011: the posttranslational modification database
- (2010) F. Gnad et al. NUCLEIC ACIDS RESEARCH
- Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation
- (2010) Kiran Mahajan et al. PLoS One
- Estrogen Receptor Alpha Phosphorylated at Tyrosine 537 is Associated with Poor Clinical Outcome in Breast Cancer Patients Treated with Tamoxifen
- (2010) Georgios P. Skliris et al. Hormones & Cancer
- PCNA on the crossroad of cancer
- (2009) Ivaylo Stoimenov et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Cancer Osaka thyroid (Cot) phosphorylates Polo-like kinase (PLK1) at Ser137 but not at Thr210
- (2009) Binhui Wu et al. BIOLOGICAL CHEMISTRY
- Mst4 and Ezrin Induce Brush Borders Downstream of the Lkb1/Strad/Mo25 Polarization Complex
- (2009) Jean Paul ten Klooster et al. DEVELOPMENTAL CELL
- Tyrosine Phosphorylation of the Human GlutathioneS-TransferaseP1 by Epidermal Growth Factor Receptor
- (2009) Tatsunori Okamura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biochemical Control of CARM1 Enzymatic Activity by Phosphorylation
- (2009) Qin Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: Implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration
- (2009) Minho Won et al. JOURNAL OF HEPATOLOGY
- Phosphorylation on Thr-106 and NO-modification of glyoxalase I suppress the TNF-induced transcriptional activity of NF-κB
- (2009) Virginie de Hemptinne et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- The regulatory mechanism of Hsp90α secretion and its function in tumor malignancy
- (2009) Xiaofeng Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gain and loss of phosphorylation sites in human cancer
- (2008) P. Radivojac et al. BIOINFORMATICS
- BRAF V600E Disrupts AZD6244-Induced Abrogation of Negative Feedback Pathways between Extracellular Signal-Regulated Kinase and Raf Proteins
- (2008) B. B. Friday et al. CANCER RESEARCH
- Acetylation Is Indispensable for p53 Activation
- (2008) Yi Tang et al. CELL
- Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway
- (2008) Megumi Funakoshi-Tago et al. CELLULAR SIGNALLING
- The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor
- (2008) Tamara Frankenberg et al. HEPATOLOGY
- c-Abl Phosphorylates Hdmx and Regulates Its Interaction with p53
- (2008) Valentina Zuckerman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SHP-2 is a novel target of Abl kinases during cell proliferation
- (2008) S. Mitra et al. JOURNAL OF CELL SCIENCE
- Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria
- (2008) Angel L. Pey et al. JOURNAL OF CLINICAL INVESTIGATION
- Phosphorylation Increases Affinity of the Phosphodiesterase-5 Catalytic Site for Tadalafil
- (2008) E. P. Bessay et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Aromatase is phosphorylated in situ at serine-118
- (2008) Todd W. Miller et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Phosphorylation of Human Jak3 at Tyrosines 904 and 939 Positively Regulates Its Activity
- (2008) H. Cheng et al. MOLECULAR AND CELLULAR BIOLOGY
- Identification of RIP1 kinase as a specific cellular target of necrostatins
- (2008) Alexei Degterev et al. Nature Chemical Biology
- Tyr130 phosphorylation triggers Syk release from antigen receptor by long-distance conformational uncoupling
- (2008) Y. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histidine phosphorylation in biological systems
- (2007) Jennifer Puttick et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started