Insights into the evolution of lanthipeptide biosynthesis

Ribosomally Synthesized and Post-Translationally Modified Peptide Natural Products: New Insights into the Role of Leader and Core Peptides during Biosynthesis

(2013) Xiao Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

The sequence of the enterococcal cytolysin imparts unusual lanthionine stereochemistry

(2013) Weixin Tang et al.   Nature Chemical Biology

The Lantibiotic Peptide Labyrinthopeptin A1 Demonstrates Broad Anti-HIV and Anti-HSV Activity with Potential for Microbicidal Applications

(2013) Geoffrey Férir et al.   PLoS One

In vitro activity of the nisin dehydratase NisB

(2013) N. Garg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biosynthesis of the Class III Lantipeptide Catenulipeptin

(2012) Huan Wang et al.   ACS Chemical Biology

Discovery, Biosynthesis, and Engineering of Lantipeptides

(2012) Patrick J. Knerr et al.   Annual Review of Biochemistry

Generation of an actagardine A variant library through saturation mutagenesis

(2012) Steven Boakes et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Structural Characterization of Four Prochlorosins: A Novel Class of Lantipeptides Produced by Planktonic Marine Cyanobacteria

(2012) Weixin Tang et al.   BIOCHEMISTRY

Curvopeptin: A New Lanthionine-Containing Class III Lantibiotic and its Co-substrate Promiscuous Synthetase

(2012) Bartlomiej Krawczyk et al.   CHEMBIOCHEM

Characterization of New Class III Lantibiotics-Erythreapeptin, Avermipeptin and Griseopeptin from Saccharopolyspora erythraea, Streptomyces avermitilis and Streptomyces griseus Demonstrates Stepwise N-Terminal Leader Processing

(2012) Ginka H. Völler et al.   CHEMBIOCHEM

Deuterium Labeled Peptides Give Insights into the Directionality of Class III Lantibiotic Synthetase LabKC

(2012) Bartlomiej Krawczyk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

Evolution of lanthipeptide synthetases

(2012) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy of the New Lantibiotic NAI-107 in Experimental Infections Induced by Multidrug-Resistant Gram-Positive Pathogens

(2011) Daniela Jabés et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanistic Studies of Ser/Thr Dehydration Catalyzed by a Member of the LanL Lanthionine Synthetase Family

(2011) Yuki Goto et al.   BIOCHEMISTRY

Labyrinthopeptins: A New Class of Carbacyclic Lantibiotics

(2010) Kathrin Meindl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vitro Biosynthesis of the Prepeptide of Type-III Lantibiotic Labyrinthopeptin A2 Including Formation of a CC Bond as a Post-Translational Modification

(2010) Wolfgang M. Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family

(2010) Daniel H Haft et al.   BMC BIOLOGY

Morphogenetic Signaling Molecules of the Streptomycetes

(2010) Joanne M. Willey et al.   CHEMICAL REVIEWS

Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria

(2010) B. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

To protect peptide pharmaceuticals against peptidases

(2010) R. Rink et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Discovery of Unique Lanthionine Synthetases Reveals New Mechanistic and Evolutionary Insights

(2010) Yuki Goto et al.   PLOS BIOLOGY

Emerging Treatments in Cystic Fibrosis

(2009) Andrew M. Jones et al.   DRUGS

Directionality and Coordination of Dehydration and Ring Formation during Biosynthesis of the Lantibiotic Nisin

(2009) Jacek Lubelski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distributive and Directional Behavior of Lantibiotic Synthetases Revealed by High-Resolution Tandem Mass Spectrometry

(2009) M. Violet Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Follow the leader: the use of leader peptides to guide natural product biosynthesis

(2009) Trent J Oman et al.   Nature Chemical Biology

The Importance of the Leader Sequence for Directing Lanthionine Formation in Lacticin 481†

(2008) Gregory C. Patton et al.   BIOCHEMISTRY

Use of lantibiotic synthetases for the preparation of bioactive constrained peptides

(2008) Matthew R. Levengood et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Determining the Structure and Mode of Action of Microbisporicin, a Potent Lantibiotic Active Against Multiresistant Pathogens

(2008) Franca Castiglione et al.   CHEMISTRY & BIOLOGY