WD40 Repeat Proteins: Signalling Scaffold with Diverse Functions

A RACK1-like protein regulates hyphal morphogenesis, root entry and in vivo virulence in Verticillium dahliae

(2017) Lei Yuan et al.   FUNGAL GENETICS AND BIOLOGY

Glial-Specific Functions of Microcephaly Protein WDR62 and Interaction with the Mitotic Kinase AURKA Are Essential for Drosophila Brain Growth

(2017) Nicholas R. Lim et al.   Stem Cell Reports

GSK3β and ERK regulate the expression of 78 kDa SG2NA and ectopic modulation of its level affects phases of cell cycle

(2017) Shweta Pandey et al.   Scientific Reports

Prokaryotic and Highly-Repetitive WD40 Proteins: A Systematic Study

(2017) Xue-Jia Hu et al.   Scientific Reports

Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 Small GTPase phosphorylation and activation

(2016) Canjun Zeng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

WD40-repeat protein MoCreC is essential for carbon repression and is involved in conidiation, growth and pathogenicity of Magnaporthe oryzae

(2016) Khalid Abdelkarim Omer Matar et al.   CURRENT GENETICS

Asc1p/RACK1 Connects Ribosomes to Eukaryotic Phosphosignaling

(2016) Kerstin Schmitt et al.   MOLECULAR AND CELLULAR BIOLOGY

RNAi-mediated silencing of the Arabidopsis thaliana ULCS1 gene, encoding a WDR protein, results in cell wall modification impairment and plant infertility

(2016) Despoina Beris et al.   PLANT SCIENCE

Structural Basis for Substrate Selectivity of the E3 Ligase COP1

(2016) Sacha Uljon et al.   STRUCTURE

SG2NA enhances cancer cell survival by stabilizing DJ-1 and thus activating Akt

(2015) Goutam Kumar Tanti et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Gβ-like protein CpcB is required for hyphal growth, conidiophore morphology and pathogenicity in Aspergillus fumigatus

(2015) Zhen-dong Cai et al.   FUNGAL GENETICS AND BIOLOGY

A WD40-repeat protein unique to malaria parasites associates with adhesion protein complexes and is crucial for blood stage progeny

(2015) Andreas von Bohl et al.   MALARIA JOURNAL

LACK, a RACK1 ortholog, facilitates cytochrome c oxidase subunit expression to promoteLeishmania majorfitness

(2015) Daviel Cardenas et al.   MOLECULAR MICROBIOLOGY

Wdr1-mediated cell shape dynamics and cortical tension are essential for epidermal planar cell polarity

(2015) Chen Luxenburg et al.   NATURE CELL BIOLOGY

MSI1 functions in a HDAC complex to fine-tune ABA signaling

(2015) Saher Mehdi et al.   PLANT CELL

The TWD40-2 protein and the AP2 complex cooperate in the clathrin-mediated endocytosis of cellulose synthase to regulate cellulose biosynthesis

(2015) Logan Bashline et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Change your Tplate, change your fate: plant CME and beyond

(2015) Yi Zhang et al.   TRENDS IN PLANT SCIENCE

A Cardiomyocyte-Specific Wdr1 Knockout Demonstrates Essential Functional Roles for Actin Disassembly during Myocardial Growth and Maintenance in Mice

(2014) Baiyin Yuan et al.   AMERICAN JOURNAL OF PATHOLOGY

Silencing of STRN4 suppresses the malignant characteristics of cancer cells

(2014) Meihong Wong et al.   CANCER SCIENCE

GMF Promotes Leading-Edge Dynamics and Collective Cell Migration In Vivo

(2014) Minna Poukkula et al.   CURRENT BIOLOGY

A Fungal Sarcolemmal Membrane-Associated Protein (SLMAP) Homolog Plays a Fundamental Role in Development and Localizes to the Nuclear Envelope, Endoplasmic Reticulum, and Mitochondria

(2014) Steffen Nordzieke et al.   EUKARYOTIC CELL

Downregulation of striatin leads to hyperphosphorylation of MAP2, induces depolymerization of microtubules and inhibits proliferation of HEK293T cells

(2014) Julia Kaźmierczak-Barańska et al.   FEBS LETTERS

SG2NA recruits DJ-1 and Akt into the mitochondria and membrane to protect cells from oxidative damage

(2014) Goutam Kumar Tanti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Making new molecules—evolution of structures for novel metabolites in plants

(2013) Daniel J Kliebenstein   CURRENT OPINION IN PLANT BIOLOGY

PfSec13 is an unusual chromatin-associated nucleoporin of Plasmodium falciparum that is essential for parasite proliferation in human erythrocytes

(2013) N. Dahan-Pasternak et al.   JOURNAL OF CELL SCIENCE

The pleiotropic effect of WD-40 domain containing proteins on cellular differentiation and production of secondary metabolites in Streptomyces coelicolor

(2013) Aleš Ulrych et al.   Molecular BioSystems

HAM-2 and HAM-3 are central for the assembly of theNeurospora STRIPAK complex at the nuclear envelope and regulate nuclear accumulation of the MAP kinase MAK-1 in a MAK-2-dependent manner

(2013) Anne Dettmann et al.   MOLECULAR MICROBIOLOGY

Functional Interplay BetweenArabidopsisNADPH Oxidases and Heterotrimeric G Protein

(2013) Miguel Angel Torres et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Mechanisms and function of substrate recruitment by F-box proteins

(2013) Jeffrey R. Skaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Heterotrimeric G Proteins Serve as a Converging Point in Plant Defense Signaling Activated by Multiple Receptor-Like Kinases

(2013) J. Liu et al.   PLANT PHYSIOLOGY

Arabidopsis Heterotrimeric G-Proteins Play a Critical Role in Host and Nonhost Resistance against Pseudomonas syringae Pathogens

(2013) Seonghee Lee et al.   PLoS One

Eukaryotic G Protein Signaling Evolved to Require G Protein-Coupled Receptors for Activation

(2013) W. Bradford et al.   Science Signaling

Msi1-Like (MSIL) Proteins in Fungi

(2013) Dong-Hoon Yang et al.   MYCOBIOLOGY

Genomic survey, expression profile and co-expression network analysis of OsWD40 family in rice

(2012) Yidan Ouyang et al.   BMC GENOMICS

Misshapen-like kinase 1 (MINK1) Is a Novel Component of Striatin-interacting Phosphatase and Kinase (STRIPAK) and Is Required for the Completion of Cytokinesis

(2012) Toshinori Hyodo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

RACK1, A multifaceted scaffolding protein: Structure and function

(2011) David R Adams et al.   Cell Communication and Signaling

Molecular cloning and characterization of a receptor for activated protein kinase C1 (RACK1) from Chinese white shrimp; Fenneropenaeus chinensis

(2011) Qian Ren et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

LEUNIG_HOMOLOG and LEUNIG Regulate Seed Mucilage Extrusion in ArabidopsisF

(2011) Minh Bui et al.   Journal of Integrative Plant Biology

A seven-WD40 protein related to human RACK1 regulates mating and virulence in Ustilago maydis

(2011) Lei Wang et al.   MOLECULAR MICROBIOLOGY

Arabidopsis Heterotrimeric G-protein Regulates Cell Wall Defense and Resistance to Necrotrophic Fungi

(2011) Magdalena Delgado-Cerezo et al.   Molecular Plant

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

Structure and function of WD40 domain proteins

(2011) Chao Xu et al.   Protein & Cell

Overexpression of MIP2, a novel WD-repeat protein, promotes proliferation of H9c2 cells

(2010) Xing Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genes encoding a striatin-like protein (ham-3) and a forkhead associated protein (ham-4) are required for hyphal fusion in Neurospora crassa

(2010) Anna R. Simonin et al.   FUNGAL GENETICS AND BIOLOGY

Structure of the Sec13–Sec16 edge element, a template for assembly of the COPII vesicle coat

(2010) James R.R. Whittle et al.   JOURNAL OF CELL BIOLOGY

A WD-Repeat Protein Stabilizes ORC Binding to Chromatin

(2010) Zhen Shen et al.   MOLECULAR CELL

A Direct Interaction with NEDD1 Regulates γ-Tubulin Recruitment to the Centrosome

(2010) Jantina A. Manning et al.   PLoS One

WD40 proteins propel cellular networks

(2010) Christian U. Stirnimann et al.   TRENDS IN BIOCHEMICAL SCIENCES

Nicotiana tabacum TTG1 contributes to ParA1-induced signalling and cell death in leaf trichomes

(2009) Y. Wang et al.   JOURNAL OF CELL SCIENCE

A function for AAMP in Nod2-mediated NF-κB activation

(2009) H. Bielig et al.   MOLECULAR IMMUNOLOGY

The WD40 Repeat Protein NEDD1 Functions in Microtubule Organization during Cell Division in Arabidopsis thaliana

(2009) C.J. T. Zeng et al.   PLANT CELL

Dual functions ofNicotiana benthamianaRae1 in interphase and mitosis

(2009) Jae-Yong Lee et al.   PLANT JOURNAL

Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming

(2009) Uri Ashery et al.   TRENDS IN NEUROSCIENCES

To cell cycle, swing the APC/C

(2008) Renske van Leuken et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

The TTG1-bHLH-MYB complex controls trichome cell fate and patterning through direct targeting of regulatory loci

(2008) M. Zhao et al.   DEVELOPMENT

WDR1 presence in the songbird basilar papilla

(2008) Henry J. Adler et al.   HEARING RESEARCH

GpMyoF, a WD40 Repeat-Containing Myosin Associated with the Myonemes of Gregarina polymorpha

(2008) Matthew B. Heintzelman et al.   JOURNAL OF PARASITOLOGY

The RACK1 signal anchor protein fromTrypanosoma bruceiassociates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis

(2008) Sandesh Regmi et al.   MOLECULAR MICROBIOLOGY

SMART 6: recent updates and new developments

(2008) I. Letunic et al.   NUCLEIC ACIDS RESEARCH

Heterotrimeric G proteins-mediated resistance to necrotrophic pathogens includes mechanisms independent of salicylic acid-, jasmonic acid/ethylene- and abscisic acid-mediated defense signaling

(2008) Yuri Trusov et al.   PLANT JOURNAL

The plant innate immunity response in stomatal guard cells invokes G-protein-dependent ion channel regulation

(2008) Wei Zhang et al.   PLANT JOURNAL

Involvement of Arabidopsis HOS15 in histone deacetylation and cold tolerance

(2008) J. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA