Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 Small GTPase phosphorylation and activation

Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation

(2016) Shaohong Cheng et al.   ENDOCRINOLOGY

Identification of biallelicLRRK1mutations in osteosclerotic metaphyseal dysplasia and evidence for locus heterogeneity

(2016) Aritoshi Iida et al.   JOURNAL OF MEDICAL GENETICS

PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2

(2015) Hiroshi Hanafusa et al.   NATURE CELL BIOLOGY

LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation

(2014) A. M. Schreij et al.   EMBO REPORTS

LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends

(2014) S. Kedashiro et al.   JOURNAL OF CELL SCIENCE

Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain

(2014) G. Piccoli et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis

(2013) Weirong Xing et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Integrin-linked kinase at a glance

(2012) M. Widmaier et al.   JOURNAL OF CELL SCIENCE

Rac1 Protein Rescues Neurite Retraction Caused by G2019S Leucine-rich Repeat Kinase 2 (LRRK2)

(2011) Diane Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rac deletion in osteoclasts causes severe osteopetrosis

(2011) M. Croke et al.   JOURNAL OF CELL SCIENCE

Bisphosphonate treatment delays stress fracture remodeling in the rat ulna

(2011) L.J. Kidd et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Bisphosphonate Use and Atypical Fractures of the Femoral Shaft

(2011) Jörg Schilcher et al.   NEW ENGLAND JOURNAL OF MEDICINE

Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor

(2011) Hiroshi Hanafusa et al.   Nature Communications

Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors

(2010) S. B. Lizarraga et al.   DEVELOPMENT

Atypical Fractures as a Potential Complication of Long-term Bisphosphonate Therapy

(2010) Deborah E. Sellmeyer   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Osteoclast-specific inactivation of the integrin-linked kinase (ILK) inhibits bone resorption

(2010) Tanya Dossa et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Osteonecrosis of the jaws induced by anti-RANK ligand therapy

(2009) K.H. Taylor et al.   BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Ephrin B1 Regulates Bone Marrow Stromal Cell Differentiation and Bone Formation by Influencing TAZ Transactivation via Complex Formation with NHERF1

(2009) W. Xing et al.   MOLECULAR AND CELLULAR BIOLOGY

Protinfo PPC: A web server for atomic level prediction of protein complexes

(2009) Weerayuth Kittichotirat et al.   NUCLEIC ACIDS RESEARCH

The WD40 Domain Is Required for LRRK2 Neurotoxicity

(2009) Nathan D. Jorgensen et al.   PLoS One

Bisphosphonate-Induced Osteopetrosis: Novel Bone Modeling Defects, Metaphyseal Osteopenia, and Osteosclerosis Fractures After Drug Exposure Ceases

(2008) Michael P Whyte et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

(2008) J. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA