Zoledronic acid influences growth, migration and invasive activity of prostate cancer cells in vitro

Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways

(2011) Radhamani Kannaiyan et al.   APOPTOSIS

The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms

(2011) Zaklina Kovacevic et al.   CARCINOGENESIS

Anti-tumour and anti-angiogenetic effects of zoledronic acid on human non-small-cell lung cancer cell line

(2011) M. Di Salvatore et al.   CELL PROLIFERATION

Subcellular localization of p27 and prostate cancer recurrence: automated digital microscopy analysis of tissue microarrays

(2011) Viju Ananthanarayanan et al.   HUMAN PATHOLOGY

Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation

(2011) Zi Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bisphosphonate stimulation of osteoblasts and osteoblastic metastasis as a mechanism of hypocalcaemia

(2011) Joon Wee Ho   MEDICAL HYPOTHESES

ADAM17 regulates prostate cancer cell proliferation through mediating cell cycle progression by EGFR/PI3K/AKT pathway

(2011) Ping Lin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Zoledronic Acid Preserves Bone Structure and Increases Survival but Does Not Limit Tumour Incidence in a Prostate Cancer Bone Metastasis Model

(2011) Tzong-Tyng Hung et al.   PLoS One

Zoledronic Acid Potentiates mTOR Inhibition and Abolishes the Resistance of Osteosarcoma Cells to RAD001 (Everolimus): Pivotal Role of the Prenylation Process

(2010) G. Moriceau et al.   CANCER RESEARCH

Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype

(2010) Srirupa Roy et al.   CELL CYCLE

ZEB1 Coordinately Regulates Laminin-332 and β4 Integrin Expression Altering the Invasive Phenotype of Prostate Cancer Cells

(2010) Justin M. Drake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The α2β1 integrin is a metastasis suppressor in mouse models and human cancer

(2010) Norma E. Ramirez et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of apoptosis-related molecules by synergistic combination of all-trans retinoic acid and zoledronic acid in hormone-refractory prostate cancer cell lines

(2010) Bulent Karabulut et al.   MOLECULAR BIOLOGY REPORTS

Increased anti-tumour effects of doxorubicin and zoledronic acid in prostate cancer cells in vitro: supporting the benefits of combination therapy

(2009) Rhys D. Clyburn et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Cyr61 downmodulation potentiates the anticancer effects of zoledronic acid in androgen-independent prostate cancer cells

(2009) Monica Marra et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of p21waf1/cip1, p27kip1, p63 and Androgen Receptor in Low and High Gleason Score Prostate Cancer

(2009) Imre Romics et al.   PATHOLOGY & ONCOLOGY RESEARCH

The bisphosphonate zoledronic acid inhibits the growth of HCT-116 colon carcinoma cells and induces tumor cell apoptosis

(2008) Lilian Sewing et al.   APOPTOSIS

RAD001 (Everolimus) inhibits growth of prostate cancer in the bone and the inhibitory effects are increased by combination with docetaxel and zoledronic acid

(2008) Todd M. Morgan et al.   PROSTATE

Zoledronic acid is unable to induce apoptosis, but slows tumor growth and prolongs survival for non-small-cell lung cancers

(2007) Ying-Ying Li et al.   LUNG CANCER