Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation

mTOR Complex-2 Activates ENaC by Phosphorylating SGK1

(2010) M. Lu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice

(2009) David A. Guertin et al.   CANCER CELL

Starving the Addiction: New Opportunities for Durable Suppression of AR Signaling in Prostate Cancer

(2009) K. E. Knudsen et al.   CLINICAL CANCER RESEARCH

Androgen Receptor Phosphorylation and Activity Are Regulated by an Association with Protein Phosphatase 1

(2009) Shaoyong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) Regulates Adipocyte Differentiation via Forkhead Box O1

(2009) Natalia Di Pietro et al.   MOLECULAR ENDOCRINOLOGY

Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/− mice

(2009) Hongbo Wang et al.   NATURE GENETICS

Differential Requirement of mTOR in Postmitotic Tissues and Tumorigenesis

(2009) C. Nardella et al.   Science Signaling

Role of a Novel PH-Kinase Domain Interface in PKB/Akt Regulation: Structural Mechanism for Allosteric Inhibition

(2009) Véronique Calleja et al.   PLOS BIOLOGY

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

(2008) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic

(2008) A. B. Sherk et al.   CANCER RESEARCH

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

(2008) Tsuneo Ikenoue et al.   EMBO JOURNAL

PP2A Regulates the Pro-apoptotic Activity of FOXO1

(2008) Ling Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation

(2008) Feng Hong et al.   MOLECULAR CELL

Mechanisms mediating androgen receptor reactivation after castration

(2008) Xin Yuan et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS