Inhibition of RSK/YB-1 signaling enhances the anti-cancer effect of enzalutamide in prostate cancer

A Novel Antiandrogen, Compound 30, Suppresses Castration-Resistant and MDV3100-Resistant Prostate Cancer Growth In Vitro and In Vivo

(2013) H. Kuruma et al.   MOLECULAR CANCER THERAPEUTICS

Interaction between docetaxel resistance and castration resistance in prostate cancer: Implications of twist1, YB-1, and androgen receptor

(2013) Masaki Shiota et al.   PROSTATE

Pro-survival and anti-apoptotic properties of androgen receptor signaling by oxidative stress promote treatment resistance in prostate cancer

(2012) Masaki Shiota et al.   ENDOCRINE-RELATED CANCER

Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: exploratory analysis of data from the COU-AA-301 randomised trial

(2012) Christopher J Logothetis et al.   LANCET ONCOLOGY

Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study

(2012) Karim Fizazi et al.   LANCET ONCOLOGY

Androgen receptor (AR) aberrations in castration-resistant prostate cancer

(2012) Kati K. Waltering et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy

(2012) Howard I. Scher et al.   NEW ENGLAND JOURNAL OF MEDICINE

Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy

(2012) Charles J. Ryan et al.   NEW ENGLAND JOURNAL OF MEDICINE

MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition

(2012) A Astanehe et al.   ONCOGENE

Targeting p90 Ribosomal S6 Kinase Eliminates Tumor-Initiating Cells by Inactivating Y-Box Binding Protein-1 in Triple-Negative Breast Cancers

(2012) Anna L. Stratford et al.   STEM CELLS

Regulation and function of the RSK family of protein kinases

(2011) Yves Romeo et al.   BIOCHEMICAL JOURNAL

Small Molecule Inhibitors Targeting the “Achilles' Heel” of Androgen Receptor Activity: Figure 1.

(2011) Marianne D. Sadar   CANCER RESEARCH

Androgen Receptor Cofactors in Prostate Cancer: Potential Therapeutic Targets of Castration-Resistant Prostate Cancer

(2011) Masaki Shiota et al.   CURRENT CANCER DRUG TARGETS

Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy

(2011) Changmeng Cai et al.   ENDOCRINE-RELATED CANCER

Y-box binding protein-1 promotes castration-resistant prostate cancer growth via androgen receptor expression

(2011) M. Shiota et al.   ENDOCRINE-RELATED CANCER

Increased androgen receptor transcription: a cause of castration-resistant prostate cancer and a possible therapeutic target

(2011) Masaki Shiota et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Antioxidant Therapy Alleviates Oxidative Stress by Androgen Deprivation and Prevents Conversion From Androgen Dependent to Castration Resistant Prostate Cancer

(2011) Masaki Shiota et al.   JOURNAL OF UROLOGY

Abiraterone and Increased Survival in Metastatic Prostate Cancer

(2011) Johann S. de Bono et al.   NEW ENGLAND JOURNAL OF MEDICINE

Twist1 and Y-box-binding protein-1 promote malignant potential in bladder cancer cells

(2010) Masaki Shiota et al.   BJU INTERNATIONAL

An update on androgen deprivation therapy for prostate cancer

(2010) Nima Sharifi et al.   ENDOCRINE-RELATED CANCER

The expression of activated Y-box binding protein-1 serine 102 mediates trastuzumab resistance in breast cancer cells by increasing CD44+ cells

(2010) J Dhillon et al.   ONCOGENE

RSK in tumorigenesis: Connections to steroid signaling

(2010) T.S. Karin Eisinger-Mathason et al.   STEROIDS

Fibroblast Growth Factor Receptor 1-Transformed Mammary Epithelial Cells Are Dependent on RSK Activity for Growth and Survival

(2009) W. Xian et al.   CANCER RESEARCH

Programmed Cell Death Protein 4 Down-regulates Y-Box Binding Protein-1 Expression via a Direct Interaction with Twist1 to Suppress Cancer Cell Growth

(2009) M. Shiota et al.   CANCER RESEARCH

Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression

(2009) M Shiota et al.   ONCOGENE

Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival

(2008) J. H. Law et al.   CANCER RESEARCH

The RSK factors of activating the Ras/MAPK signaling cascade

(2008) Audrey Carriere   Frontiers in Bioscience-Landmark

Endothelin-1 enhances the expression of the androgen receptor via activation of the c-mycpathway in prostate cancer cells

(2008) June G. Lee et al.   MOLECULAR CARCINOGENESIS