Hedgehog signaling is active in human prostate cancer stroma and regulates proliferation and differentiation of adjacent epithelium

A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer

(2013) Ashlee K. Clark et al.   BIOMATERIALS

A preclinical xenograft model of prostate cancer using human tumors

(2013) Mitchell G Lawrence et al.   Nature Protocols

Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling

(2012) N. B. Hassounah et al.   CLINICAL CANCER RESEARCH

Human Epithelial Basal Cells Are Cells of Origin of Prostate Cancer, Independent of CD133 Status

(2012) Renea A. Taylor et al.   STEM CELLS

Inhibition of Hedgehog Signaling Decreases Proliferation and Clonogenicity of Human Mesenchymal Stem Cells

(2011) Magali Plaisant et al.   PLoS One

Paracrine hedgehog increases the steroidogenic potential of prostate stromal cells in a Gli-dependent manner

(2011) Elina Levina et al.   PROSTATE

Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells

(2011) Katsumi Shigemura et al.   PROSTATE

Trafficking to the Ciliary Membrane: How to Get Across the Periciliary Diffusion Barrier?

(2010) Maxence V. Nachury et al.   Annual Review of Cell and Developmental Biology

The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts

(2009) A Shaw et al.   ONCOGENE

Regulation of Prostatic Stem Cells by Stromal Niche in Health and Disease

(2008) Gail P. Risbridger et al.   ENDOCRINOLOGY

Sonic Hedgehog-responsive Genes in the Fetal Prostate

(2008) Min Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE

Hedgehog Signaling Alters Adipocyte Maturation of Human Mesenchymal Stem Cells

(2008) Coralie Fontaine et al.   STEM CELLS

Activation of Hedgehog Signaling Inhibits Osteoblast Differentiation of Human Mesenchymal Stem Cells

(2008) Magali Plaisant et al.   STEM CELLS