Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2

Prognostic relevance of receptor tyrosine kinase expression in breast cancer: A meta-analysis

(2014) Arnoud J. Templeton et al.   CANCER TREATMENT REVIEWS

Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC

(2014) Katherine R. Amato et al.   JOURNAL OF CLINICAL INVESTIGATION

Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma

(2014) Georgina V. Long et al.   NEW ENGLAND JOURNAL OF MEDICINE

EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties

(2014) H Miao et al.   ONCOGENE

EPHA2 Is a Mediator of Vemurafenib Resistance and a Novel Therapeutic Target in Melanoma

(2014) B. Miao et al.   Cancer Discovery

Ligand-Independent EPHA2 Signaling Drives the Adoption of a Targeted Therapy-Mediated Metastatic Melanoma Phenotype

(2014) K. H. T. Paraiso et al.   Cancer Discovery

The p90 RSK Family Members: Common Functions and Isoform Specificity

(2013) R. Lara et al.   CANCER RESEARCH

RSK Isoforms in Cancer Cell Invasion and Metastasis

(2013) F. J. Sulzmaier et al.   CANCER RESEARCH

Inverse correlation between Thr-669 and constitutive tyrosine phosphorylation in the asymmetric epidermal growth factor receptor dimer conformation

(2013) Kanae Sato et al.   CANCER SCIENCE

Phosphorylation of Serine 779 in Fibroblast Growth Factor Receptor 1 and 2 by Protein Kinase Cϵ Regulates Ras/Mitogen-activated Protein Kinase Signaling and Neuronal Differentiation

(2013) Ana Lonic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EphA2 promotes epithelial–mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer cells

(2013) J Huang et al.   ONCOGENE

RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789

(2013) B Nadratowska-Wesolowska et al.   ONCOGENE

ERK-Mediated Phosphorylation of Fibroblast Growth Factor Receptor 1 on Ser777 Inhibits Signaling

(2013) M. Zakrzewska et al.   Science Signaling

Ephexin4-mediated promotion of cell migration and anoikis resistance is regulated by serine 897 phosphorylation of EphA2

(2013) Hiromu Kawai et al.   FEBS Open Bio

A Rising Cancer Prevention Target of RSK2 in Human Skin Cancer

(2013) Narayanasamy Arul et al.   Frontiers in Oncology

The EphA2 Receptor Drives Self-Renewal and Tumorigenicity in Stem-like Tumor-Propagating Cells from Human Glioblastomas

(2012) Elena Binda et al.   CANCER CELL

RSK2 Protein Suppresses Integrin Activation and Fibronectin Matrix Assembly and Promotes Cell Migration

(2012) Joanna E. Gawecka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation

(2012) Ping Li et al.   MOLECULAR BIOLOGY OF THE CELL

Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma

(2012) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting p90 Ribosomal S6 Kinase Eliminates Tumor-Initiating Cells by Inactivating Y-Box Binding Protein-1 in Triple-Negative Breast Cancers

(2012) Anna L. Stratford et al.   STEM CELLS

Targeting of TAK1 in inflammatory disorders and cancer

(2012) Hiroaki Sakurai   TRENDS IN PHARMACOLOGICAL SCIENCES

Oncogenic Pathways, Molecularly Targeted Therapies, and Highlighted Clinical Trials in Non–Small-Cell Lung Cancer (NSCLC)

(2011) Thanyanan Reungwetwattana et al.   Clinical Lung Cancer

Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase

(2011) Kohei Harada et al.   EXPERIMENTAL CELL RESEARCH

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

BRAFV600E: Implications for Carcinogenesis and Molecular Therapy

(2011) E. R. Cantwell-Dorris et al.   MOLECULAR CANCER THERAPEUTICS

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Epha2 is a critical oncogene in melanoma

(2011) D Udayakumar et al.   ONCOGENE

EphA receptor signaling—Complexity and emerging themes

(2011) Hui Miao et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

(2010) Sonja J. Heidorn et al.   CELL

Emerging strategies for EphA2 receptor targeting for cancer therapeutics

(2010) Manish Tandon et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism

(2010) Nao Hiramoto-Yamaki et al.   JOURNAL OF CELL BIOLOGY

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

(2010) Poulikos I. Poulikakos et al.   NATURE

Improved Phos-tag SDS-PAGE under neutral pH conditions for advanced protein phosphorylation profiling

(2010) Eiji Kinoshita et al.   PROTEOMICS

Up-regulation of EphA2 and down-regulation of EphrinA1 are associated with the aggressive phenotype and poor prognosis of malignant glioma

(2010) Xia Li et al.   TUMOR BIOLOGY

EphA2 Mediates Ligand-Dependent Inhibition and Ligand-Independent Promotion of Cell Migration and Invasion via a Reciprocal Regulatory Loop with Akt

(2009) Hui Miao et al.   CANCER CELL

EphA2 in the Early Pathogenesis and Progression of Non-Small Cell Lung Cancer

(2009) J. M. Brannan et al.   Cancer Prevention Research

Expression of the Receptor Tyrosine Kinase EphA2 Is Increased in Smokers and Predicts Poor Survival in Non-Small Cell Lung Cancer

(2009) J. M. Brannan et al.   CLINICAL CANCER RESEARCH

TAK1-Mediated Serine/Threonine Phosphorylation of Epidermal Growth Factor Receptor via p38/Extracellular Signal-Regulated Kinase: NF- B-Independent Survival Pathways in Tumor Necrosis Factor Alpha Signaling

(2009) M. Nishimura et al.   MOLECULAR AND CELLULAR BIOLOGY

RSK Is a Principal Effector of the RAS-ERK Pathway for Eliciting a Coordinate Promotile/Invasive Gene Program and Phenotype in Epithelial Cells

(2009) Ulrik Doehn et al.   MOLECULAR CELL

The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain

(2009) Monica Red Brewer et al.   MOLECULAR CELL

Eph/ephrin signaling in epithelial development and homeostasis

(2008) Hui Miao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

(2008) Dana M. Brantley-Sieders et al.   JOURNAL OF CLINICAL INVESTIGATION