Advances in microRNAs and TP53 Gene Regulatory Network*

MicroRNA-34a Modulates c-Myc Transcriptional Complexes to Suppress Malignancy in Human Prostate Cancer Cells

(2012) Soichiro Yamamura et al.   PLoS One

TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome

(2011) F. G. Rucker et al.   BLOOD

MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma

(2011) Soichiro Yamamura et al.   CARCINOGENESIS

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

(2011) Junli Liu et al.   CELL

Association of a MicroRNA/TP53 Feedback Circuitry With Pathogenesis and Outcome of B-Cell Chronic Lymphocytic Leukemia

(2011) Muller Fabbri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The miRNA expression profile of the uveal melanoma

(2011) ChengHsun Yang et al.   Science China-Life Sciences

Long-term ex vivo monitoring of in vivo microRNA activity in liver using a secreted luciferase sensor

(2011) Gang Wang et al.   Science China-Life Sciences

MicroRNAs in NF- B signaling

(2011) X. Ma et al.   Journal of Molecular Cell Biology

Tumor suppressor p53 meets microRNAs

(2011) Z. Feng et al.   Journal of Molecular Cell Biology

Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene friend leukemia virus integration 1 gene

(2010) Jianjun Zhang et al.   CANCER

microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network

(2010) Liming Zhang et al.   CARCINOGENESIS

MicroRNA Profiling Reveals Two Distinct p53-Related Human Pluripotent Stem Cell States

(2010) Pierre Neveu et al.   Cell Stem Cell

Negative Regulation of Tumor Suppressor p53 by MicroRNA miR-504

(2010) Wenwei Hu et al.   MOLECULAR CELL

miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma

(2010) Alexander Swarbrick et al.   NATURE MEDICINE

Negative regulation of the tumor suppressor p53 gene by microRNAs

(2010) M Kumar et al.   ONCOGENE

MicroRNA-145 Targets YES and STAT1 in Colon Cancer Cells

(2010) Lea H. Gregersen et al.   PLoS One

The Tumor Suppressors p53, p63, and p73 Are Regulators of MicroRNA Processing Complex

(2010) Lakshmanane Boominathan   PLoS One

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

(2010) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meiotic Recombination Provokes Functional Activation of the p53 Regulatory Network

(2010) W.-J. Lu et al.   SCIENCE

Structural characteristics of the hydrophobic patch of azurin and its interaction with p53: a site-directed spin labeling study

(2010) Chao Xu et al.   Science China-Life Sciences

Marek’s disease virus-encoded microRNAs: genomics, expression and function

(2010) Jun Luo et al.   Science China-Life Sciences

microRNA-181b targets MLK2 in HL-60 cells

(2010) Hong Chen et al.   Science China-Life Sciences

The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein

(2010) Zhaohui Feng et al.   TRENDS IN CELL BIOLOGY

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1

(2009) R. Garzon et al.   BLOOD

MicroRNA-145 Suppresses Cell Invasion and Metastasis by Directly Targeting Mucin 1

(2009) M. Sachdeva et al.   CANCER RESEARCH

MiR-122/Cyclin G1 Interaction Modulates p53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells

(2009) F. Fornari et al.   CANCER RESEARCH

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

miR-15a and miR-16-1 in cancer: discovery, function and future perspectives

(2009) R I Aqeilan et al.   CELL DEATH AND DIFFERENTIATION

The p53 Pathway Encounters the MicroRNA World

(2009) Apana Takwi et al.   CURRENT GENOMICS

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

(2009) Hong-li Yan et al.   EMBO JOURNAL

MicroRNA-125b is a novel negative regulator of p53

(2009) M. T.N. Le et al.   GENES & DEVELOPMENT

miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities

(2009) M Mraz et al.   LEUKEMIA

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

p53 represses c-Myc through induction of the tumor suppressor miR-145

(2009) M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma

(2008) W. Xiong et al.   BLOOD

miR-34a as part of the resistance network in chronic lymphocytic leukemia

(2008) T. Zenz et al.   BLOOD

miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells

(2008) Na Li et al.   CANCER LETTERS

Coordinated Regulation of Cell Cycle Transcripts by p53-Inducible microRNAs, miR-192 and miR-215

(2008) S. A. Georges et al.   CANCER RESEARCH

p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

(2008) C. J. Braun et al.   CANCER RESEARCH

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

(2008) T. Papagiannakopoulos et al.   CANCER RESEARCH

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

Getting to the Root of miRNA-Mediated Gene Silencing

(2008) Ana Eulalio et al.   CELL

Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

(2008) Rajini Mudhasani et al.   JOURNAL OF CELL BIOLOGY

An Epstein-Barr virus–encoded microRNA targets PUMA to promote host cell survival

(2008) Elizabeth Yee-Wai Choy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma

(2008) Richard J Flavin et al.   MODERN PATHOLOGY

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

(2008) Qihong Huang et al.   NATURE CELL BIOLOGY

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

miR-29 miRNAs activate p53 by targeting p85α and CDC42

(2008) Seong-Yeon Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MiR-15a and miR-16-1 cluster functions in human leukemia

(2008) George A. Calin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins

(2008) S. Sengupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA