The desensitization gate of inhibitory Cys-loop receptors

Crystal structure of a human GABAA receptor

(2014) Paul S. Miller et al.   NATURE

Structural mechanism of glutamate receptor activation and desensitization

(2014) Joel R. Meyerson et al.   NATURE

X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors

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Conformational Transitions Underlying Pore Opening and Desensitization in Membrane-embeddedGloeobacter violaceusLigand-gated Ion Channel (GLIC)

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Benzodiazepines Modulate GABAA Receptors by Regulating the Preactivation Step after GABA Binding

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China must provide education on HIV

(2012) Jian Zhang et al.   NATURE

Structure and Pharmacology of Pentameric Receptor Channels: From Bacteria to Brain

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Activation and Desensitization Induce Distinct Conformational Changes at the Extracellular-Transmembrane Domain Interface of the Glycine Receptor

(2011) Qian Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cl−concentration changes and desensitization of GABAAand glycine receptors

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Single-Channel and Structural Foundations of Neuronal  7 Acetylcholine Receptor Potentiation

(2011) C. J. B. daCosta et al.   JOURNAL OF NEUROSCIENCE

Desensitization of neurotransmitter-gated ion channels during high-frequency stimulation: a comparative study of Cys-loop, AMPA and purinergic receptors

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Investigation of the Molecular Mechanism of the  7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator PNU-120596 Provides Evidence for Two Distinct Desensitized States

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Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

The GABA system in anxiety and depression and its therapeutic potential

(2011) Hanns Möhler   NEUROPHARMACOLOGY

Agonist activation of  7 nicotinic acetylcholine receptors via an allosteric transmembrane site

(2011) J. K. Gill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct activities of GABA agonists at synaptic- and extrasynaptic-type GABAAreceptors

(2010) Martin Mortensen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Structural mechanism of C-type inactivation in K+ channels

(2010) Luis G. Cuello et al.   NATURE

Nicotine addiction and nicotinic receptors: lessons from genetically modified mice

(2010) Jean-Pierre Changeux   NATURE REVIEWS NEUROSCIENCE

Mutations affecting GABAergic signaling in seizures and epilepsy

(2010) Aristea S. Galanopoulou   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Binding, activation and modulation of Cys-loop receptors

(2010) Paul S. Miller et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Interface between Extracellular and Transmembrane Domains of Homomeric Cys-Loop Receptors Governs Open-Channel Lifetime and Rate of Desensitization

(2008) C. Bouzat et al.   JOURNAL OF NEUROSCIENCE

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

Surface Mobility of Postsynaptic AMPARs Tunes Synaptic Transmission

(2008) M. Heine et al.   SCIENCE

Aromatic residues at position 55 of rat α7 nicotinic acetylcholine receptors are critical for maintaining rapid desensitization

(2007) Elaine A. Gay et al.   JOURNAL OF PHYSIOLOGY-LONDON