Direct quantitative detection of Doc2b-induced hemifusion in optically trapped membranes

Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system

(2012) Minjoung Kyoung et al.   Nature Protocols

Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages

(2012) Y. Gao et al.   SCIENCE

Quantifying how DNA stretches, melts and changes twist under tension

(2011) Peter Gross et al.   Nature Physics

Doc2 Supports Spontaneous Synaptic Transmission by a Ca2+-Independent Mechanism

(2011) Zhiping P. Pang et al.   NEURON

Synaptotagmin Increases the Dynamic Range of Synapses by Driving Ca2+-Evoked Release and by Clamping a Near-Linear Remaining Ca2+ Sensor

(2011) Olexiy Kochubey et al.   NEURON

In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release

(2011) M. Kyoung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Ca2+ sensors in secretion: teammates, competitors or autocrats?

(2011) Alexander M. Walter et al.   TRENDS IN NEUROSCIENCES

Interaction of Synaptotagmin with Lipid Bilayers, Analyzed by Single-Molecule Force Spectroscopy

(2010) Hirohide Takahashi et al.   BIOPHYSICAL JOURNAL

Doc2b Is a High-Affinity Ca2+ Sensor for Spontaneous Neurotransmitter Release

(2010) A. J. Groffen et al.   SCIENCE

Lipid Mixing and Content Release in Single-Vesicle, SNARE-Driven Fusion Assay with 1–5 ms Resolution

(2009) Tingting Wang et al.   BIOPHYSICAL JOURNAL

Synaptotagmin-Mediated Bending of the Target Membrane Is a Critical Step in Ca2+-Regulated Fusion

(2009) Enfu Hui et al.   CELL

The Hydrophobic Insertion Mechanism of Membrane Curvature Generation by Proteins

(2008) Felix Campelo et al.   BIOPHYSICAL JOURNAL

Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+

(2008) Michael C Chicka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Productive Hemifusion Intermediates in Fast Vesicle Fusion Driven by Neuronal SNAREs

(2007) Tingting Liu et al.   BIOPHYSICAL JOURNAL