A Disalicylic Acid-Furanyl Derivative Inhibits Ephrin Binding to a Subset of Eph Receptors

Eph Receptors and Ephrin Signaling Pathways: A Role in Bone Homeostasis

(2012) Claire M. Edwards et al.   International Journal of Medical Sciences

The resurgence of covalent drugs

(2011) Juswinder Singh et al.   NATURE REVIEWS DRUG DISCOVERY

Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation

(2011) Carmine Giorgio et al.   PLoS One

Structure−Activity Relationship Analysis of Peptides Targeting the EphA2 Receptor

(2010) Sayantan Mitra et al.   BIOCHEMISTRY

Functional significance of VEGF-a in human ovarian carcinoma: Role in vasculogenic mimicry

(2010) Jun-yan Wang et al.   CANCER BIOLOGY & THERAPY

EphA2 as a promoter of melanoma tumorigenicity

(2010) Naira V. Margaryan et al.   CANCER BIOLOGY & THERAPY

False Positives in the Early Stages of Drug Discovery

(2010) R. Sink et al.   CURRENT MEDICINAL CHEMISTRY

Emerging strategies for EphA2 receptor targeting for cancer therapeutics

(2010) Manish Tandon et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rational Design of a Selective Covalent Modifier of G Protein    Subunits

(2010) A. L. Dessal et al.   MOLECULAR PHARMACOLOGY

Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells

(2010) Jonathan W. Astin et al.   NATURE CELL BIOLOGY

The EphB4 receptor promotes the growth of melanoma cells expressing the ephrin-B2 ligand

(2010) Nai-Ying Yang et al.   Pigment Cell & Melanoma Research

Therapeutic interference with EphrinB2 signalling inhibits oxygen-induced angioproliferative retinopathy

(2009) Christoph Ehlken et al.   ACTA OPHTHALMOLOGICA

Preferential Induction of EphB4 over EphB2 and Its Implication in Colorectal Cancer Progression

(2009) S. R. Kumar et al.   CANCER RESEARCH

The road less traveled: modulating signal transduction enzymes by inhibiting their protein–protein interactions

(2009) Michelle R Arkin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity

(2009) Haina Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport

(2009) Alessandro Filosa et al.   NATURE NEUROSCIENCE

Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport

(2009) M. A. Carmona et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-Specific Information Processing in Segregating Populations of Eph Receptor Ephrin-Expressing Cells

(2009) C. Jorgensen et al.   SCIENCE

Eph-Ephrin Bidirectional Signaling in Physiology and Disease

(2008) Elena B. Pasquale   CELL

Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor

(2008) Haina Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors

(2008) Roberta Noberini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The EphA2 Receptor and EphrinA1 Ligand in Solid Tumors: Function and Therapeutic Targeting

(2008) J. Wykosky et al.   MOLECULAR CANCER RESEARCH