Network of mutually repressive metastasis regulators can promote cell heterogeneity and metastatic transitions

Roadblocks to translational advances on metastasis research

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MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination

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Polycomb Protein EZH2 Regulates Tumor Invasion via the Transcriptional Repression of the Metastasis Suppressor RKIP in Breast and Prostate Cancer

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Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer

(2012) Steven A. Frank et al.   PLOS BIOLOGY

Mapping the Environmental Fitness Landscape of a Synthetic Gene Circuit

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Cellular Decision Making and Biological Noise: From Microbes to Mammals

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Mechanisms of nitric oxide-mediated inhibition of EMT in cancer

(2011) Stavroula Baritaki et al.   CELL CYCLE

Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer

(2011) Jieun Yun et al.   EMBO JOURNAL

The BTB and CNC Homology 1 (BACH1) Target Genes Are Involved in the Oxidative Stress Response and in Control of the Cell Cycle

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Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Origins of regulated cell-to-cell variability

(2011) Berend Snijder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gene Expression Noise Facilitates Adaptation and Drug Resistance Independently of Mutation

(2011) Daniel A. Charlebois et al.   PHYSICAL REVIEW LETTERS

Dynamical and Structural Analysis of a T Cell Survival Network Identifies Novel Candidate Therapeutic Targets for Large Granular Lymphocyte Leukemia

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A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

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Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

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Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

(2009) Sabrina L. Spencer et al.   NATURE

Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours

(2009) Amy Brock et al.   NATURE REVIEWS GENETICS

Bistability, Epigenetics, and Bet-Hedging in Bacteria

(2008) Jan-Willem Veening et al.   Annual Review of Microbiology

Histone deacetylase inhibitors: mechanism of action and therapeutic use in cancer

(2008) Olaia Martínez-Iglesias et al.   Clinical & Translational Oncology

Raf kinase inhibitory protein (RKIP): A physiological regulator and future therapeutic target

(2008) Lingchun Zeng et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

A noncytotoxic DsRed variant for whole-cell labeling

(2008) Rita L Strack et al.   NATURE METHODS

Bach1 inhibits oxidative stress–induced cellular senescence by impeding p53 function on chromatin

(2008) Yoshihiro Dohi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamic Proteomics of Individual Cancer Cells in Response to a Drug

(2008) A. A. Cohen et al.   SCIENCE