Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function

HCN channels: new roles in sinoatrial node function

(2014) Christian Wahl-Schott et al.   CURRENT OPINION IN PHARMACOLOGY

A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP

(2014) Madoka Akimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness

(2014) Marco Lolicato et al.   Nature Chemical Biology

A Secondary Structural Transition in the C-helix Promotes Gating of Cyclic Nucleotide-regulated Ion Channels

(2013) Michael C. Puljung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of the auxiliary subunit TRIP8b to HCN channels shifts the mode of action of cAMP

(2013) Lei Hu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Prefrontal Cortex HCN1 Channels Enable Intrinsic Persistent Neural Firing and Executive Memory Function

(2013) S. J. Thuault et al.   JOURNAL OF NEUROSCIENCE

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Neuromodulation of Ih in Layer II Medial Entorhinal Cortex Stellate Cells: A Voltage-Clamp Study

(2012) J. G. Heys et al.   JOURNAL OF NEUROSCIENCE

Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels

(2012) J. R. Bankston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tetramerization Dynamics of C-terminal Domain Underlies Isoform-specific cAMP Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels

(2011) Marco Lolicato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Energetics of Cyclic AMP Binding to HCN Channel C Terminus Reveal Negative Cooperativity

(2011) Sarah S. Chow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trafficking and Gating of Hyperpolarization-activated Cyclic Nucleotide-gated Channels Are Regulated by Interaction with Tetratricopeptide Repeat-containing Rab8b-interacting Protein (TRIP8b) and Cyclic AMP at Distinct Sites

(2011) Ye Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIP8b Regulates HCN1 Channel Trafficking and Gating through Two Distinct C-Terminal Interaction Sites

(2011) B. Santoro et al.   JOURNAL OF NEUROSCIENCE

Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel

(2011) S. Schunke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternatively Spliced Isoforms of TRIP8b Differentially Control h Channel Trafficking and Function

(2009) A. S. Lewis et al.   JOURNAL OF NEUROSCIENCE

Mapping the structure and conformational movements of proteins with transition metal ion FRET

(2009) Justin W Taraska et al.   NATURE METHODS

Association with the Auxiliary Subunit PEX5R/Trip8b Controls Responsiveness of HCN Channels to cAMP and Adrenergic Stimulation

(2009) Gerd Zolles et al.   NEURON

TRIP8b Splice Variants Form a Family of Auxiliary Subunits that Regulate Gating and Trafficking of HCN Channels in the Brain

(2009) Bina Santoro et al.   NEURON

Hyperpolarization-Activated Cation Channels: From Genes to Function

(2009) Martin Biel et al.   PHYSIOLOGICAL REVIEWS

Control of Cardiac Rate by “Funny” Channels in Health and Disease

(2008) Andrea Barbuti et al.   Annals of the New York Academy of Sciences

Solution Structure of the Iron−Sulfur Cluster Cochaperone HscB and Its Binding Surface for the Iron−Sulfur Assembly Scaffold Protein IscU†‡

(2008) Anna K. Füzéry et al.   BIOCHEMISTRY

C-terminal Movement during Gating in Cyclic Nucleotide-modulated Channels

(2008) Kimberley B. Craven et al.   JOURNAL OF BIOLOGICAL CHEMISTRY