An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function

Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells

(2013) A. S. McKee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Murine regulatory T cells differ from conventional T cells in resisting the CTLA-4 reversal of TCR stop-signal

(2012) Y. Lu et al.   BLOOD

Marginating Dendritic Cells of the Tumor Microenvironment Cross-Present Tumor Antigens and Stably Engage Tumor-Specific T Cells

(2012) John J. Engelhardt et al.   CANCER CELL

Peripheral tolerance and autoimmunity: lessons from in vivo imaging

(2012) Jordan Jacobelli et al.   IMMUNOLOGIC RESEARCH

Functional Specialization of Islet Dendritic Cell Subsets

(2012) N. Yin et al.   JOURNAL OF IMMUNOLOGY

Autoreactive Cytotoxic T Lymphocytes Acquire Higher Expression of Cytotoxic Effector Markers in the Islets of NOD Mice after Priming in Pancreatic Lymph Nodes

(2011) Kate L. Graham et al.   AMERICAN JOURNAL OF PATHOLOGY

Expression and Regulation of Chemokines in Murine and Human Type 1 Diabetes

(2011) S. A. Sarkar et al.   DIABETES

Intravital imaging of CTLs killing islet cells in diabetic mice

(2011) Ken Coppieters et al.   JOURNAL OF CLINICAL INVESTIGATION

PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

(2011) Taku Okazaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Accelerated Autoimmune Diabetes in the Absence of LAG-3

(2011) M. Bettini et al.   JOURNAL OF IMMUNOLOGY

Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response

(2011) B. Calderon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans

(2011) B. Calderon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics

(2010) Rachel S. Friedman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antiviral CD8+T cell effector activities in situ are regulated by target cell type

(2010) Matthew M. Hufford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Duration of antigen receptor signaling determines T-cell tolerance or activation

(2010) S. D. Katzman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic Cell Antigen Presentation Drives Simultaneous Cytokine Production by Effector and Regulatory T Cells in Inflamed Skin

(2009) James B. McLachlan et al.   IMMUNITY

Amplification of Autoimmune Response through Induction of Dendritic Cell Maturation in Inflamed Tissues

(2009) K. Melli et al.   JOURNAL OF IMMUNOLOGY

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

(2009) Ingo Bartholomäus et al.   NATURE

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

(2009) Brian T Fife et al.   NATURE IMMUNOLOGY

Dendritic cells in islets of Langerhans constitutively present   cell-derived peptides bound to their class II MHC molecules

(2008) B. Calderon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues

(2008) L. M. Wakim et al.   SCIENCE