Chromosome 3p loss of heterozygosity is associated with a unique metabolic network in clear cell renal carcinoma

Genome-scale modeling of human metabolism - a systems biology approach

(2013) Adil Mardinoglu et al.   Biotechnology Journal

Integration of clinical data with a genome-scale metabolic model of the human adipocyte

(2013) A. Mardinoglu et al.   Molecular Systems Biology

Comprehensive molecular characterization of clear cell renal cell carcinoma

(2013)   NATURE

Heterogeneity of tumor-induced gene expression changes in the human metabolic network

(2013) Jie Hu et al.   NATURE BIOTECHNOLOGY

Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods

(2013) Leif Väremo et al.   NUCLEIC ACIDS RESEARCH

Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model

(2013) F. Danielsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stimulation of de Novo Pyrimidine Synthesis by Growth Signaling Through mTOR and S6K1

(2013) I. Ben-Sahra et al.   SCIENCE

Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis

(2013) A. M. Robitaille et al.   SCIENCE

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

The RAVEN Toolbox and Its Use for Generating a Genome-scale Metabolic Model for Penicillium chrysogenum

(2013) Rasmus Agren et al.   PLoS Computational Biology

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Predicting Drug Targets and Biomarkers of Cancer via Genome-Scale Metabolic Modeling

(2012) L. Jerby et al.   CLINICAL CANCER RESEARCH

State of the Science: An Update on Renal Cell Carcinoma

(2012) E. Jonasch et al.   MOLECULAR CANCER RESEARCH

Therapeutic targets in cancer cell metabolism and autophagy

(2012) Heesun Cheong et al.   NATURE BIOTECHNOLOGY

Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer

(2012) Sakari Vanharanta et al.   NATURE MEDICINE

Constraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods

(2012) Nathan E. Lewis et al.   NATURE REVIEWS MICROBIOLOGY

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cscan: finding common regulators of a set of genes by using a collection of genome-wide ChIP-seq datasets

(2012) Federico Zambelli et al.   NUCLEIC ACIDS RESEARCH

Reconstruction of Genome-Scale Active Metabolic Networks for 69 Human Cell Types and 16 Cancer Types Using INIT

(2012) Rasmus Agren et al.   PLoS Computational Biology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Predicting selective drug targets in cancer through metabolic networks

(2011) O. Folger et al.   Molecular Systems Biology

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

(2011) Christian Frezza et al.   NATURE

R-Gada: a fast and flexible pipeline for copy number analysis in association studies

(2010) Roger Pique-Regi et al.   BMC BIOINFORMATICS

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE