Integration of clinical data with a genome-scale metabolic model of the human adipocyte

CardioNet: A human metabolic network suited for the study of cardiomyocyte metabolism

(2012) Anja Karlstädt et al.   BMC Systems Biology

A Whole-Cell Computational Model Predicts Phenotype from Genotype

(2012) Jonathan R. Karr et al.   CELL

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

Adipose Tissue Resting Energy Expenditure and Expression of Genes Involved in Mitochondrial Function Are Higher in Women than in Men

(2012) Intawat Nookaew et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Therapeutic targets in cancer cell metabolism and autophagy

(2012) Heesun Cheong et al.   NATURE BIOTECHNOLOGY

Proteomic characterization of adipose tissue constituents, a necessary step for understanding adipose tissue complexity

(2012) Juan R. Peinado et al.   PROTEOMICS

Mitochondrial dysfunction in white adipose tissue

(2012) Christine M. Kusminski et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Reconstruction of Genome-Scale Active Metabolic Networks for 69 Human Cell Types and 16 Cancer Types Using INIT

(2012) Rasmus Agren et al.   PLoS Computational Biology

Applications of Mass Spectrometry to Lipids and Membranes

(2011) Richard Harkewicz et al.   Annual Review of Biochemistry

A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology

(2011) Aarash Bordbar et al.   BMC Systems Biology

Translational and systems medicine

(2011) J. Nielsen   JOURNAL OF INTERNAL MEDICINE

Systems medicine and metabolic modelling

(2011) A. Mardinoglu et al.   JOURNAL OF INTERNAL MEDICINE

Dynamics of human adipose lipid turnover in health and metabolic disease

(2011) Peter Arner et al.   NATURE

Forming functional fat: a growing understanding of adipocyte differentiation

(2011) Ana G. Cristancho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation

(2011) D. A. Gross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compartmentalization of the Edinburgh Human Metabolic Network

(2010) Tong Hao et al.   BMC BIOINFORMATICS

Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity: A Driver for Ectopic Fat Deposition?

(2010) S. E. McQuaid et al.   DIABETES

Pharmaceutical interventions for obesity: a public health perspective

(2010) E. Caveney et al.   DIABETES OBESITY & METABOLISM

Characterization of the Human Adipocyte Proteome and Reproducibility of Protein Abundance by One-Dimensional Gel Electrophoresis and HPLC−ESI−MS/MS

(2010) Xitao Xie et al.   JOURNAL OF PROTEOME RESEARCH

HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology

(2010) Christoph Gille et al.   Molecular Systems Biology

Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructions

(2010) Aarash Bordbar et al.   Molecular Systems Biology

Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism

(2010) Livnat Jerby et al.   Molecular Systems Biology

Large-scale in silico modeling of metabolic interactions between cell types in the human brain

(2010) Nathan E Lewis et al.   NATURE BIOTECHNOLOGY

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

A protocol for generating a high-quality genome-scale metabolic reconstruction

(2010) Ines Thiele et al.   Nature Protocols

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases

(2010) Yihai Cao   NATURE REVIEWS DRUG DISCOVERY

Ensembl 2011

(2010) P. Flicek et al.   NUCLEIC ACIDS RESEARCH

Ongoing and future developments at the Universal Protein Resource

(2010)   NUCLEIC ACIDS RESEARCH

Reactome: a database of reactions, pathways and biological processes

(2010) D. Croft et al.   NUCLEIC ACIDS RESEARCH

Creation of an antibody-based subcellular protein atlas

(2010) Emma Lundberg et al.   PROTEOMICS

Drug Off-Target Effects Predicted Using Structural Analysis in the Context of a Metabolic Network Model

(2010) Roger L. Chang et al.   PLoS Computational Biology

Sampling the Solution Space in Genome-Scale Metabolic Networks Reveals Transcriptional Regulation in Key Enzymes

(2010) Sergio Bordel et al.   PLoS Computational Biology

ALK7 expression is specific for adipose tissue, reduced in obesity and correlates to factors implicated in metabolic disease

(2009) Lena M.S. Carlsson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lipid Droplets Finally Get a Little R-E-S-P-E-C-T

(2009) Robert V. Farese et al.   CELL

Resistance to Diet-Induced Obesity in Mice with Synthetic Glyoxylate Shunt

(2009) Jason T. Dean et al.   Cell Metabolism

Systems biology of lipid metabolism: From yeast to human

(2009) Jens Nielsen   FEBS LETTERS

Advances in adipose tissue metabolism

(2009) M Lafontan   INTERNATIONAL JOURNAL OF OBESITY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

KEGG for representation and analysis of molecular networks involving diseases and drugs

(2009) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Systems medicine: the future of medical genomics and healthcare

(2009) Charles Auffray et al.   Genome Medicine

Obesity causes a shift in metabolic flow of gangliosides in adipose tissues

(2008) Aya Tanabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

(2008) Haiming Cao et al.   CELL

Impaired Glucose Tolerance and Insulin Resistance Are Associated With Increased Adipose 11 -Hydroxysteroid Dehydrogenase Type 1 Expression and Elevated Hepatic 5 -Reductase Activity

(2008) J. W. Tomlinson et al.   DIABETES

Progesterone metabolism in adipose cells

(2008) Yonghua Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

HMDB: a knowledgebase for the human metabolome

(2008) D. S. Wishart et al.   NUCLEIC ACIDS RESEARCH