Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain -ketoacid dehydrogenase kinase
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain -ketoacid dehydrogenase kinase
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 110, Issue 24, Pages 9728-9733
Publisher
Proceedings of the National Academy of Sciences
Online
2013-05-29
DOI
10.1073/pnas.1303220110
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Clinical and Experimental Applications of Sodium Phenylbutyrate
- (2013) Tommaso Iannitti et al. Drugs in research & development
- Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance
- (2012) Christopher B. Newgard Cell Metabolism
- Branched-Chain and Aromatic Amino Acids Are Predictors of Insulin Resistance in Young Adults
- (2012) P. Wurtz et al. DIABETES CARE
- Structural and Biochemical Characterization of Human Mitochondrial Branched-chain α-Ketoacid Dehydrogenase Phosphatase
- (2012) R. Max Wynn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tissue-specific and Nutrient Regulation of the Branched-chain α-Keto Acid Dehydrogenase Phosphatase, Protein Phosphatase 2Cm (PP2Cm)
- (2012) Meiyi Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Urinary phenylacetylglutamine as dosing biomarker for patients with urea cycle disorders
- (2012) M. Mokhtarani et al. MOLECULAR GENETICS AND METABOLISM
- Hypothalamic Leucine Metabolism Regulates Liver Glucose Production
- (2011) Y. Su et al. DIABETES
- Clofibrate-Induced Reduction of Plasma Branched-Chain Amino Acid Concentrations Impairs Glucose Tolerance in Rats
- (2011) Yoshihiro Kadota et al. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
- Metabolite profiles and the risk of developing diabetes
- (2011) Thomas J Wang et al. NATURE MEDICINE
- Catabolism of Branched-Chain Amino Acids in Heart Failure: Insights from Genetic Models
- (2011) Haipeng Sun et al. PEDIATRIC CARDIOLOGY
- Phenylbutyrate therapy for maple syrup urine disease
- (2010) Nicola Brunetti-Pierri et al. HUMAN MOLECULAR GENETICS
- A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
- (2009) Christopher B. Newgard et al. Cell Metabolism
- Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells
- (2009) Gang Lu et al. JOURNAL OF CLINICAL INVESTIGATION
- Regulation of branched-chain amino acid catabolism in rat models for spontaneous type 2 diabetes mellitus
- (2008) Teiji Kuzuya et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Pyruvate Dehydrogenase Kinase-4 Structures Reveal a Metastable Open Conformation Fostering Robust Core-free Basal Activity
- (2008) R. Max Wynn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started