ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer

Tumor Cell Dissemination: Emerging Biological Insights from Animal Models and Cancer Patients

(2013) Yibin Kang et al.   CANCER CELL

Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee

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Punctuated Evolution of Prostate Cancer Genomes

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ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients

(2013) E. Baena et al.   GENES & DEVELOPMENT

ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss

(2013) Yu Chen et al.   NATURE MEDICINE

ETV1, 4 and 5: An oncogenic subfamily of ETS transcription factors

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Modeling prostate cancer in mice: something old, something new, something premalignant, something metastatic

(2012) Shazia Irshad et al.   CANCER AND METASTASIS REVIEWS

B-Raf Activation Cooperates with PTEN Loss to Drive c-Myc Expression in Advanced Prostate Cancer

(2012) J. Wang et al.   CANCER RESEARCH

A Comprehensive Survey of Ras Mutations in Cancer

(2012) I. A. Prior et al.   CANCER RESEARCH

Pten Loss and RAS/MAPK Activation Cooperate to Promote EMT and Metastasis Initiated from Prostate Cancer Stem/Progenitor Cells

(2012) D. J. Mulholland et al.   CANCER RESEARCH

Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases

(2012) Zhihu Ding et al.   CELL

EMT and Dissemination Precede Pancreatic Tumor Formation

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The mutational landscape of lethal castration-resistant prostate cancer

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Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

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PEA3/ETV4-related transcription factors coupled with active ERK signalling are associated with poor prognosis in gastric adenocarcinoma

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Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin

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Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells

(2011) P. C. Hollenhorst et al.   GENES & DEVELOPMENT

Common Gene Rearrangements in Prostate Cancer

(2011) Mark A. Rubin et al.   JOURNAL OF CLINICAL ONCOLOGY

Polyomavirus enhancer activator 3 protein promotes breast cancer metastatic progression through Snail-induced epithelial-mesenchymal transition

(2011) Hiu-Fung Yuen et al.   JOURNAL OF PATHOLOGY

COP1 is a tumour suppressor that causes degradation of ETS transcription factors

(2011) Alberto C. Vitari et al.   NATURE

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

Molecular sampling of prostate cancer: a dilemma for predicting disease progression

(2010) Andrea Sboner et al.   BMC Medical Genomics

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

An Ets2-Driven Transcriptional Program in Tumor-Associated Macrophages Promotes Tumor Metastasis

(2010) T. Zabuawala et al.   CANCER RESEARCH

Molecular genetics of prostate cancer: new prospects for old challenges

(2010) M. M. Shen et al.   GENES & DEVELOPMENT

Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma

(2010) Jo Eyles et al.   JOURNAL OF CLINICAL INVESTIGATION

The ERK MAP kinase-PEA3/ETV4-MMP-1 axis is operative in oesophageal adenocarcinoma

(2010) Richard Keld et al.   Molecular Cancer

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

(2010) Peter J. Campbell et al.   NATURE

An oncogene–tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB

(2010) Junxia Min et al.   NATURE MEDICINE

Reactome: a database of reactions, pathways and biological processes

(2010) D. Croft et al.   NUCLEIC ACIDS RESEARCH

Disseminated Tumor Cells in Prostate Cancer Patients after Radical Prostatectomy and without Evidence of Disease Predicts Biochemical Recurrence

(2009) T. M. Morgan et al.   CLINICAL CANCER RESEARCH

A luminal epithelial stem cell that is a cell of origin for prostate cancer

(2009) Xi Wang et al.   NATURE

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

(2009) Jennifer C King et al.   NATURE GENETICS

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

(2009) Brett S Carver et al.   NATURE GENETICS

ETS gene fusions in prostate cancer

(2009) Jeremy P. Clark et al.   Nature Reviews Urology

ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

(2009) Y. Zong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systemic Spread Is an Early Step in Breast Cancer

(2008) Yves Hüsemann et al.   CANCER CELL

Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer

(2008) X. Ouyang et al.   CANCER RESEARCH

Integrating differentiation and cancer: The Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis

(2008) Cory Abate-Shen et al.   DIFFERENTIATION

The PTEN–PI3K pathway: of feedbacks and cross-talks

(2008) A Carracedo et al.   ONCOGENE

Unravelling the tumor-suppressive functions of FOXO proteins

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