ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss

ERG Cooperates with Androgen Receptor in Regulating Trefoil Factor 3 in Prostate Cancer Disease Progression

(2015) David S. Rickman et al.   NEOPLASIA

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

(2013) Changmeng Cai et al.   JOURNAL OF CLINICAL INVESTIGATION

A transcriptional repressor co-regulatory network governing androgen response in prostate cancers

(2012) Kern Rei Chng et al.   EMBO JOURNAL

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

TMPRSS2- Driven ERG Expression In Vivo Increases Self-Renewal and Maintains Expression in a Castration Resistant Subpopulation

(2012) Orla M. Casey et al.   PLoS One

Genome-wide DNA Methylation Events in TMPRSS2–ERG Fusion-Negative Prostate Cancers Implicate an EZH2-Dependent Mechanism with miR-26a Hypermethylation

(2012) Stefan T. Börno et al.   Cancer Discovery

DREME: motif discovery in transcription factor ChIP-seq data

(2011) Timothy L. Bailey   BIOINFORMATICS

Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth

(2011) David J. Mulholland et al.   CANCER CELL

Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer

(2011) Brett S. Carver et al.   CANCER CELL

Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage

(2011) Wen-Hui Lien et al.   Cell Stem Cell

Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

(2011) Biswajyoti Sahu et al.   EMBO JOURNAL

FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer

(2011) Paula Paulo et al.   GENES CHROMOSOMES & CANCER

Dynamic Nucleosome-Depleted Regions at Androgen Receptor Enhancers in the Absence of Ligand in Prostate Cancer Cells

(2011) C. Andreu-Vieyra et al.   MOLECULAR AND CELLULAR BIOLOGY

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

(2011) Dong Wang et al.   NATURE

MYC Cooperates with AKT in Prostate Tumorigenesis and Alters Sensitivity to mTOR Inhibitors

(2011) Nicola J. Clegg et al.   PLoS One

An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression

(2010) Jindan Yu et al.   CANCER CELL

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study

(2010) Howard I Scher et al.   LANCET

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours

(2010) Ping Chi et al.   NATURE

Induction of Prostatic Intraepithelial Neoplasia and Modulation of Androgen Receptor by ETS Variant 1/ETS-Related Protein 81

(2009) S. Shin et al.   CANCER RESEARCH

Histone modifications at human enhancers reflect global cell-type-specific gene expression

(2009) Nathaniel D. Heintzman et al.   NATURE

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

(2009) Jennifer C King et al.   NATURE GENETICS

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

(2009) Brett S Carver et al.   NATURE GENETICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

(2009) Y. Zong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 Gene Fusions in Prostate Cancer

(2008) B. E. Helgeson et al.   CANCER RESEARCH

FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription

(2008) Mathieu Lupien et al.   CELL

Characterization of TMPRSS2-ERG Fusion High-Grade Prostatic Intraepithelial Neoplasia and Potential Clinical Implications

(2008) J.-M. Mosquera et al.   CLINICAL CANCER RESEARCH

A causal role for ERG in neoplastic transformation of prostate epithelium

(2008) O. Klezovitch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY

Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

(2008) Scott A. Tomlins et al.   NEOPLASIA