Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death
Published 2013 View Full Article
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Title
Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 110, Issue 45, Pages E4203-E4212
Publisher
Proceedings of the National Academy of Sciences
Online
2013-10-22
DOI
10.1073/pnas.1310001110
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Note: Only part of the references are listed.- HIPK2: A tumour suppressor that controls DNA damage-induced cell fate and cytokinesis
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- (2012) G Sorrentino et al. CELL DEATH AND DIFFERENTIATION
- Updates on HIPK2: a resourceful oncosuppressor for clearing cancer
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- HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop
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- A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer
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- Zyxin Is a Critical Regulator of the Apoptotic HIPK2-p53 Signaling Axis
- (2011) J. Crone et al. CANCER RESEARCH
- HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage
- (2011) C Lazzari et al. ONCOGENE
- Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
- (2011) J-H Mao et al. ONCOGENE
- Cutaneous HPV23 E6 Prevents p53 Phosphorylation through Interaction with HIPK2
- (2011) Dorothea Muschik et al. PLoS One
- Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins
- (2011) Yih-Cherng Liou et al. TRENDS IN BIOCHEMICAL SCIENCES
- Stabilization of HIPK2 by escape from proteasomal degradation mediated by the E3 ubiquitin ligase Siah1
- (2009) Se-Yong Kim et al. CANCER LETTERS
- Blinded by the Light: The Growing Complexity of p53
- (2009) Karen H. Vousden et al. CELL
- Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3
- (2008) Samuel Sidi et al. CELL
- HIPK2 and cancer cell resistance to therapy
- (2008) Eva Krieghoff-Henning et al. Future Oncology
- Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR
- (2008) Melanie Winter et al. NATURE CELL BIOLOGY
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