Lysine 63-linked polyubiquitination is required for EGF receptor degradation

Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor

(2013) Li Zhang et al.   JOURNAL OF LIPID RESEARCH

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Generation and physiological roles of linear ubiquitin chains

(2012) Henning Walczak et al.   BMC BIOLOGY

Recycling of EGFR and ErbB2 is associated with impaired Hrs tyrosine phosphorylation and decreased deubiquitination by AMSH

(2012) Inez M.J. Meijer et al.   CELLULAR SIGNALLING

Governance of Endocytic Trafficking and Signaling by Reversible Ubiquitylation

(2012) Michael J. Clague et al.   DEVELOPMENTAL CELL

Dual-specificity MAP kinase phosphatases (MKPs)

(2012) Christopher J. Caunt et al.   FEBS Journal

Selectivity of the ubiquitin-binding modules

(2012) Simin Rahighi et al.   FEBS LETTERS

NMR analysis of Lys63-linked polyubiquitin recognition by the tandem ubiquitin-interacting motifs of Rap80

(2012) Naotaka Sekiyama et al.   JOURNAL OF BIOMOLECULAR NMR

A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting

(2012) Zoi Erpapazoglou et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquitin chain conformation regulates recognition and activity of interacting proteins

(2012) Yu Ye et al.   NATURE

Molecular Mechanisms of Ubiquitin-Dependent Membrane Traffic

(2011) James H. Hurley et al.   Annual Review of Biophysics

Polyubiquitination of Insulin-like Growth Factor I Receptor (IGF-IR) Activation Loop Promotes Antibody-induced Receptor Internalization and Down-regulation

(2011) Yifan Mao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination

(2011) Daniel K. Stringer et al.   JOURNAL OF CELL BIOLOGY

Structural and Thermodynamic Comparison of the Catalytic Domain of AMSH and AMSH-LP: Nearly Identical Fold but Different Stability

(2011) Christopher W. Davies et al.   JOURNAL OF MOLECULAR BIOLOGY

Lung Cancer Serum Biomarker Discovery Using Label-Free Liquid Chromatography-Tandem Mass Spectrometry

(2011) Xuemei Zeng et al.   Journal of Thoracic Oncology

Proteomic snapshot of the EGF-induced ubiquitin network

(2011) E. Argenzio et al.   Molecular Systems Biology

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

ErbB2 Trafficking and Degradation Associated with K48 and K63 Polyubiquitination

(2010) Corina Marx et al.   CANCER RESEARCH

VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo

(2010) Xuefeng Ren et al.   EMBO JOURNAL

Lysine 63-linked Polyubiquitination of the Dopamine Transporter Requires WW3 and WW4 Domains of Nedd4-2 and UBE2D Ubiquitin-conjugating Enzymes

(2010) Arnau Vina-Vilaseca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

(2010) Lai Kuan Goh et al.   JOURNAL OF CELL BIOLOGY

The ubiquitin code of yeast permease trafficking

(2010) Elsa Lauwers et al.   TRENDS IN CELL BIOLOGY

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Glucose-induced Ubiquitylation and Endocytosis of the Yeast Jen1 Transporter

(2009) Sandra Paiva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway

(2009) Elsa Lauwers et al.   JOURNAL OF CELL BIOLOGY

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

(2009) Yogesh Kulathu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ubiquitin in trafficking: The network at work

(2008) Filippo Acconcia et al.   EXPERIMENTAL CELL RESEARCH

Ubc4/5 and c-Cbl Continue to Ubiquitinate EGF Receptor after Internalization to Facilitate Polyubiquitination and Degradation

(2008) Kyohei Umebayashi et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

(2008) Yusuke Sato et al.   NATURE