LSD1/CoREST is an allosteric nanoscale clamp regulated by H3-histone-tail molecular recognition

LSD1/CoREST Reversible Opening–Closing Dynamics: Discovery of a Nanoscale Clamp for Chromatin and Protein Binding

(2012) Riccardo Baron et al.   BIOCHEMISTRY

A short Gfi-1B isoform controls erythroid differentiation by recruiting the LSD1–CoREST complex through the dimethylation of its SNAG domain

(2012) Benoît Laurent et al.   JOURNAL OF CELL SCIENCE

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

(2012) Tino Schenk et al.   NATURE MEDICINE

Complexities of occupancy and sequence

(2012) Mary Muers   NATURE REVIEWS GENETICS

Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors

(2011) M. M. Singh et al.   NEURO-ONCOLOGY

Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST Complex

(2011) Riccardo Baron et al.   STRUCTURE

Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases

(2010) Nima Mosammaparast et al.   Annual Review of Biochemistry

Demethylation of RB Regulator MYPT1 by Histone Demethylase LSD1 Promotes Cell Cycle Progression in Cancer Cells

(2010) H.-S. Cho et al.   CANCER RESEARCH

The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1

(2010) Yiwei Lin et al.   EMBO JOURNAL

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

(2010) Shinya Hayami et al.   INTERNATIONAL JOURNAL OF CANCER

POVME: An algorithm for measuring binding-pocket volumes

(2010) Jacob D. Durrant et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Histone deacetylase inhibitors as a new weapon in the arsenal of differentiation therapies of cancer

(2009) Oronza Antonietta Botrugno et al.   CANCER LETTERS

Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

(2009) J. H. Schulte et al.   CANCER RESEARCH

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

(2009) Soyoung Lim et al.   CARCINOGENESIS

LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer

(2009) Yan Wang et al.   CELL

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

(2009) X. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary history of the Snail/Scratch superfamily

(2009) Alejandro Barrallo-Gimeno et al.   TRENDS IN GENETICS

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

LSD1: oxidative chemistry for multifaceted functions in chromatin regulation

(2008) Federico Forneris et al.   TRENDS IN BIOCHEMICAL SCIENCES