Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor

Mode shift of the voltage sensors in Shaker K+channels is caused by energetic coupling to the pore domain

(2011) Georges A. Haddad et al.   JOURNAL OF GENERAL PHYSIOLOGY

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Unexpected synergism between Tetrodotoxin and μ-conotoxin in blocking voltage-gated sodium channels

(2010) Min Min Zhang et al.   Channels

Ion permeation and block of the gating pore in the voltage sensor of NaV1.4 channels with hypokalemic periodic paralysis mutations

(2010) Stanislav Sokolov et al.   JOURNAL OF GENERAL PHYSIOLOGY

Cooccupancy of the Outer Vestibule of Voltage-Gated Sodium Channels by μ-Conotoxin KIIIA and Saxitoxin or Tetrodotoxin

(2010) Min-Min Zhang et al.   JOURNAL OF NEUROPHYSIOLOGY

Structural mechanism of C-type inactivation in K+ channels

(2010) Luis G. Cuello et al.   NATURE

Structural basis for the coupling between activation and inactivation gates in K+ channels

(2010) Luis G. Cuello et al.   NATURE

The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na+channel

(2009) Ya-Chin Yang et al.   JOURNAL OF GENERAL PHYSIOLOGY

Deconstructing voltage sensor function and pharmacology in sodium channels

(2008) Frank Bosmans et al.   NATURE

S4-based voltage sensors have three major conformations

(2008) C. A. Villalba-Galea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA