Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation

Tumor Progression Locus 2 Mediates Signal-Induced Increases in Cytoplasmic Calcium and Cell Migration

(2011) M. Hatziapostolou et al.   Science Signaling

Loss of Single Immunoglobulin Interlukin-1 Receptor-Related Molecule Leads to Enhanced Colonic Polyposis in Apcmin Mice

(2010) Hui Xiao et al.   GASTROENTEROLOGY

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

Regulatory T-cell stability and plasticity in mucosal and systemic immune systems

(2010) M Murai et al.   Mucosal Immunology

ERK activation drives intestinal tumorigenesis in Apcmin/+ mice

(2010) Sung Hee Lee et al.   NATURE MEDICINE

In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction

(2010) N. R. Blatner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis

(2010) W.-J. Chae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory Lymphocytes and Intestinal Inflammation

(2009) Ana Izcue et al.   Annual Review of Immunology

Stromal regulatory T-cells are associated with a favourable prognosis in gastric cancer of the cardia

(2009) Matthias Haas et al.   BMC GASTROENTEROLOGY

T-Regulatory Cells Shift from a Protective Anti-Inflammatory to a Cancer-Promoting Proinflammatory Phenotype in Polyposis

(2009) Elias Gounaris et al.   CANCER RESEARCH

Inflammation and colorectal cancer

(2009) Sarah Kraus et al.   CURRENT OPINION IN PHARMACOLOGY

Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?

(2009) Maria A. Curotto de Lafaille et al.   IMMUNITY

Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors

(2009) Masayuki Fukata et al.   INFLAMMATORY BOWEL DISEASES

TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells

(2009) Frank Kaiser et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ablation of Tumor Progression Locus 2 Promotes a Type 2 Th Cell Response in Ovalbumin-Immunized Mice

(2009) Wendy T. Watford et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

(2009) Masako Murai et al.   NATURE IMMUNOLOGY

Nitric oxide and TNF-  trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice

(2009) S. E. Erdman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NF- B as a Critical Link Between Inflammation and Cancer

(2009) M. Karin   Cold Spring Harbor Perspectives in Biology

Proteinase-Activated Receptor-1-Triggered Activation of Tumor Progression Locus-2 Promotes Actin Cytoskeleton Reorganization and Cell Migration

(2008) M. Hatziapostolou et al.   CANCER RESEARCH

The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-Induced Tumorigenesis

(2008) G. Y. Chen et al.   CANCER RESEARCH

The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response

(2008) Thomas Weichhart et al.   IMMUNITY

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

(2008) Paul Salama et al.   JOURNAL OF CLINICAL ONCOLOGY

Tpl2 kinase regulates T cell interferon-γ production and host resistance toToxoplasma gondii

(2008) Wendy T. Watford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Live Imaging of Cysteine-Cathepsin Activity Reveals Dynamics of Focal Inflammation, Angiogenesis, and Polyp Growth

(2008) Elias Gounaris et al.   PLoS One

Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells

(2008) C. Tsatsanis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA