Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies

A Conserved IFN-  Receptor Tyrosine Motif Directs the Biological Response to Type I IFNs

(2014) W. Zhao et al.   JOURNAL OF IMMUNOLOGY

Role of p38 Protein Kinase in the Ligand-independent Ubiquitination and Down-regulation of the IFNAR1 Chain of Type I Interferon Receptor

(2011) Sabyasachi Bhattacharya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative efficacy of a recombinant feline interferon omega in refractory cases of calicivirus-positive cats with caudal stomatitis: a randomised, multi-centre, controlled, double-blind study in 39 cats

(2011) Philippe R. Hennet et al.   JOURNAL OF FELINE MEDICINE AND SURGERY

Interferon: Current Status and Future Prospects in Cancer Therapy

(2011) Ben X. Wang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

A critical appraisal of treatment decisions in multiple sclerosis—old versus new

(2011) Bernd C. Kieseier et al.   Nature Reviews Neurology

Inflammatory signaling compromises cell responses to interferon alpha

(2011) W-C HuangFu et al.   ONCOGENE

Pathogen Recognition Receptor Signaling Accelerates Phosphorylation-Dependent Degradation of IFNAR1

(2011) Juan Qian et al.   PLoS Pathogens

Identification of New Substrates of the Protein-tyrosine Phosphatase PTP1B by Bayesian Integration of Proteome Evidence

(2010) Emanuela Ferrari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Ligand-Stimulated Downregulation of the Alpha Interferon Receptor: Role of Protein Kinase D2

(2010) H. Zheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Melanoma cell-secreted soluble factor that stimulates ubiquitination and degradation of the interferon alpha receptor and attenuates its signaling

(2010) Wei-Chun HuangFu et al.   Pigment Cell & Melanoma Research

Virus-Induced Unfolded Protein Response Attenuates Antiviral Defenses via Phosphorylation-Dependent Degradation of the Type I Interferon Receptor

(2009) Jianghuai Liu et al.   Cell Host & Microbe

Inducible Priming Phosphorylation Promotes Ligand-independent Degradation of the IFNAR1 Chain of Type I Interferon Receptor

(2009) Sabyasachi Bhattacharya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of Bartonella species, feline calicivirus, and feline herpesvirus 1 infection with gingivostomatitis in cats

(2009) Kristy L. Dowers et al.   JOURNAL OF FELINE MEDICINE AND SURGERY

Mammalian Casein Kinase 1  and Its Leishmanial Ortholog Regulate Stability of IFNAR1 and Type I Interferon Signaling

(2009) J. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Ligand-independent pathway that controls stability of interferon alpha receptor

(2008) Jianghuai Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor

(2008) Yongxin Han et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling

(2008) X. Lu et al.   BLOOD

Targeting PTPs with small molecule inhibitors in cancer treatment

(2008) Zhong-Xing Jiang et al.   CANCER AND METASTASIS REVIEWS

Basal Ubiquitin-independent Internalization of Interferon α Receptor Is Prevented by Tyk2-mediated Masking of a Linear Endocytic Motif

(2008) K. G. Suresh Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY