cAMP response element modulator   controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

IL-23R rs11209026 polymorphism modulates IL-17A expression in patients with rheumatoid arthritis

(2011) J Hazlett et al.   GENES AND IMMUNITY

cAMP-responsive Element Modulator (CREM)α Protein Signaling Mediates Epigenetic Remodeling of the Human Interleukin-2 Gene

(2011) Christian M. Hedrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cAMP-responsive Element Modulator (CREM)α Protein Induces Interleukin 17A Expression and Mediates Epigenetic Alterations at the Interleukin-17A Gene Locus in Patients with Systemic Lupus Erythematosus

(2011) Thomas Rauen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases

(2011) Christian M. Hedrich et al.   TRENDS IN MOLECULAR MEDICINE

Transcriptional Activation of the cAMP-responsive Modulator Promoter in Human T Cells Is Regulated by Protein Phosphatase 2A-mediated Dephosphorylation of SP-1 and Reflects Disease Activity in Patients with Systemic Lupus Erythematosus

(2010) Yuang-Taung Juang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased ERK and JNK signaling contribute to gene overexpression in “senescent” CD4+CD28- T cells through epigenetic mechanisms

(2009) Yingxuan Chen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Th17 cells in infection and autoimmunity

(2009) Federica Sallusto et al.   MICROBES AND INFECTION

Distinct regulation of effector and memory T-cell differentiation

(2008) Axel Kallies   IMMUNOLOGY AND CELL BIOLOGY

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION