Analysis of neural subtypes reveals selective mitochondrial dysfunction in dopaminergic neurons from parkin mutants
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Title
Analysis of neural subtypes reveals selective mitochondrial dysfunction in dopaminergic neurons from parkin mutants
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 109, Issue 26, Pages 10438-10443
Publisher
Proceedings of the National Academy of Sciences
Online
2012-06-13
DOI
10.1073/pnas.1120688109
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Note: Only part of the references are listed.- Mitochondrial Dysfunction in Parkinson's Disease
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- The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons
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- Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
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- During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
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- Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
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- (2011) A. S. Rambold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
- (2011) F. H. Sterky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- To Eat or Not to Eat: Neuronal Metabolism, Mitophagy, and Parkinson's Disease
- (2010) Aaron M. Gusdon et al. ANTIOXIDANTS & REDOX SIGNALING
- The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations
- (2010) Sven Geisler et al. Autophagy
- Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
- (2010) Victor S. Van Laar et al. HUMAN MOLECULAR GENETICS
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
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- The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
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- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitophagy: the latest problem for Parkinson's disease
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- (2010) Derek P. Narendra et al. PLOS BIOLOGY
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- (2008) K. Trinh et al. JOURNAL OF NEUROSCIENCE
- Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
- (2008) Y. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1/Parkin pathway regulates mitochondrial morphology
- (2008) A. C. Poole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
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