Characterization of the nasopharyngeal carcinoma methylome identifies aberrant disruption of key signaling pathways and methylated tumor suppressor genes

Targeted p16Ink4a epimutation causes tumorigenesis and reduces survival in mice

(2014) Da-Hai Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

The genomic landscape of nasopharyngeal carcinoma

(2014) De-Chen Lin et al.   NATURE GENETICS

Double restriction-enzyme digestion improves the coverage and accuracy of genome-wide CpG methylation profiling by reduced representation bisulfite sequencing

(2013) Junwen Wang et al.   BMC GENOMICS

A comprehensive overview of Infinium HumanMethylation450 data processing

(2013) S. Dedeurwaerder et al.   BRIEFINGS IN BIOINFORMATICS

Promoter methylation status of the tumor suppressor gene SOX11 is associated with cell growth and invasion in nasopharyngeal carcinoma

(2013) Song Zhang et al.   Cancer Cell International

Batch Effects and Pathway Analysis: Two Potential Perils in Cancer Studies Involving DNA Methylation Array Analysis

(2013) K. N. Harper et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

FEZF2 , a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma

(2013) Xing-sheng Shu et al.   CARCINOGENESIS

Epigenetic identification of receptor tyrosine kinase-like orphan receptor 2 as a functional tumor suppressor inhibiting β-catenin and AKT signaling but frequently methylated in common carcinomas

(2013) Lili Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

(2013) Priscilla Brebi et al.   Epigenetics

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Characterization ofCACNA2D3as a putative tumor suppressor gene in the development and progression of nasopharyngeal carcinoma

(2013) Alissa Michelle Go Wong et al.   INTERNATIONAL JOURNAL OF CANCER

Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells

(2013) Tingxiu Xiang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Metalloprotease ADAMTS8 Displays Antitumor Properties through Antagonizing EGFR–MEK–ERK Signaling and Is Silenced in Carcinomas by CpG Methylation

(2013) Gigi C.G. Choi et al.   MOLECULAR CANCER RESEARCH

A novel 3p22.3 gene CMTM7 represses oncogenic EGFR signaling and inhibits cancer cell growth

(2013) H Li et al.   ONCOGENE

Methylation profiling of Epstein-Barr virus immediate-early gene promoters, BZLF1 and BRLF1in tumors of epithelial, NK- and B-cell origins

(2012) Lili Li et al.   BMC CANCER

Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma

(2012) Yingxi Mo et al.   CANCER LETTERS

Genome-wide CpG island methylation analyses in non-small cell lung cancer patients

(2012) Gerwin Heller et al.   CARCINOGENESIS

Patterns of aberrant DNA hypermethylation in nasopharyngeal carcinoma in Tunisian patients

(2012) S. Challouf et al.   CLINICA CHIMICA ACTA

Integrative Array-Based Approach Identifies MZB1 as a Frequently Methylated Putative Tumor Suppressor in Hepatocellular Carcinoma

(2012) S. Matsumura et al.   CLINICAL CANCER RESEARCH

Protocadherin8 is a functional tumor suppressor frequently inactivated by promoter methylation in nasopharyngeal carcinoma

(2012) Dan He et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer

(2012) W Du et al.   ONCOGENE

Familial and large-scale case–control studies identify genes associated with nasopharyngeal carcinoma

(2012) Jin-Xin Bei et al.   SEMINARS IN CANCER BIOLOGY

Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches

(2012) Kwok-Wai Lo et al.   SEMINARS IN CANCER BIOLOGY

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(2012) Qian Tao   Chinese Journal of Cancer

CDH4 as a novel putative tumor suppressor gene epigenetically silenced by promoter hypermethylation in nasopharyngeal carcinoma

(2011) Chunping Du et al.   CANCER LETTERS

Classification of Epstein-Barr Virus-Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes

(2011) K. Matsusaka et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype

(2011) Victor Chun Lam Wong et al.   INTERNATIONAL JOURNAL OF CANCER

Epigenetic markers for early detection of nasopharyngeal carcinoma in a high risk population

(2011) Susanna H Hutajulu et al.   Molecular Cancer

A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors

(2011) J S W Low et al.   ONCOGENE

The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas

(2011) L Li et al.   ONCOGENE

Epigenetic disruption of cell signaling in nasopharyngeal carcinoma

(2011) Li-Li Li et al.   Chinese Journal of Cancer

Advances in genome-wide DNA methylation analysis

(2010) Romi Gupta* et al.   BIOTECHNIQUES

Genome-wide DNA methylation profiling reveals novel epigenetically regulated genes and non-coding RNAs in human testicular cancer

(2010) H H Cheung et al.   BRITISH JOURNAL OF CANCER

KRAB Zinc Finger Protein ZNF382 Is a Proapoptotic Tumor Suppressor That Represses Multiple Oncogenes and Is Commonly Silenced in Multiple Carcinomas

(2010) Y. Cheng et al.   CANCER RESEARCH

The Tumor Suppressor UCHL1 Forms a Complex with p53/MDM2/ARF to Promote p53 Signaling and Is Frequently Silenced in Nasopharyngeal Carcinoma

(2010) L. Li et al.   CLINICAL CANCER RESEARCH

A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma

(2010) Myriam Loyo et al.   INTERNATIONAL JOURNAL OF CANCER

Epigenomics reveals a functional genome anatomy and a new approach to common disease

(2010) Andrew P Feinberg   NATURE BIOTECHNOLOGY

A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci

(2010) Jin-Xin Bei et al.   NATURE GENETICS

Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma

(2010) M R Morris et al.   ONCOGENE

Genome-wide Association Study Reveals Multiple Nasopharyngeal Carcinoma-Associated Loci within the HLA Region at Chromosome 6p21.3

(2009) Ka-Po Tse et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CMTM3, Located at the Critical Tumor Suppressor Locus 16q22.1, Is Silenced by CpG Methylation in Carcinomas and Inhibits Tumor Cell Growth through Inducing Apoptosis

(2009) Y. Wang et al.   CANCER RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

DACT3 Is an Epigenetic Regulator of Wnt/β-Catenin Signaling in Colorectal Cancer and Is a Therapeutic Target of Histone Modifications

(2008) Xia Jiang et al.   CANCER CELL

Functional Analysis of a Cell Cycle-Associated, Tumor-Suppressive Gene, Protein Tyrosine Phosphatase Receptor Type G, in Nasopharyngeal Carcinoma

(2008) A. K. L. Cheung et al.   CANCER RESEARCH

Expression of concern: Characterization of a novel epigenetically-silenced, growth-suppressive gene, ADAMTS9 , and its association with lymph node metastases in nasopharyngeal carcinoma

(2008) Hong Lok Lung et al.   INTERNATIONAL JOURNAL OF CANCER

A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis

(2008) Thomas A Down et al.   NATURE BIOTECHNOLOGY

Epigenetic disruption of interferon-γ response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas

(2008) K Y Lee et al.   ONCOGENE

Promoter hypermethylation of CCNA1, RARRES1, and HRASLS3 in nasopharyngeal carcinoma

(2007) Pattamawadee Yanatatsaneejit et al.   ORAL ONCOLOGY