Post-translational Regulation of Runx2 in Bone and Cartilage

PTHrP prevents chondrocyte premature hypertrophy by inducing cyclin-D1-dependent Runx2 and Runx3 phosphorylation, ubiquitylation and proteasomal degradation

(2009) M. Zhang et al.   JOURNAL OF CELL SCIENCE

Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells

(2008) Naoyuki Makita et al.   GENE

Ubiquitin Ligase Smurf1 Mediates Tumor Necrosis Factor-induced Systemic Bone Loss by Promoting Proteasomal Degradation of Bone Morphogenetic Signaling Proteins

(2008) Ruolin Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation

(2008) Xueni Li et al.   JOURNAL OF CELL BIOLOGY

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

(2008) Kefeng Lu et al.   NATURE CELL BIOLOGY

Phenotypic transcription factors epigenetically mediate cell growth control

(2008) S. A. Ali et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of osteogenic differentiation during skeletal development

(2007) Zhong-Liang Deng   Frontiers in Bioscience-Landmark