Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

(2014) Pratyusha Mandal et al.   MOLECULAR CELL

Role of receptor interacting protein (RIP)1 on apoptosis-inducing factor-mediated necroptosis during acetaminophen-evoked acute liver failure in mice

(2014) Ye-Fa Zhang et al.   TOXICOLOGY LETTERS

The B-RafV600E inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury

(2014) J-X Li et al.   Cell Death & Disease

Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure

(2014) Kenji Takemoto et al.   FEBS Open Bio

Necrosis-dependent and independent signaling of the RIP kinases in inflammation

(2013) Kenta Moriwaki et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Adipose tissue derived stromal stem cell therapy in murine ConA-derived hepatitis is dependent on myeloid-lineage and CD4+T-cell suppression

(2013) Mami Higashimoto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice

(2013) Anup Ramachandran et al.   HEPATOLOGY

Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis

(2013) Ricardo Weinlich et al.   Cell Reports

TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation

(2012) S Jouan-Lanhouet et al.   CELL DEATH AND DIFFERENTIATION

Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase

(2012) A Degterev et al.   CELL DEATH AND DIFFERENTIATION

Blockade of IL-33 ameliorates Con A-induced hepatic injury by reducing NKT cell activation and IFN-γ production in mice

(2012) Jie Chen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Ameliorated ConA-Induced Hepatitis in the Absence of PKC-theta

(2012) Xianfeng Fang et al.   PLoS One

A novel role for RIP1 kinase in mediating TNFα production

(2012) D E Christofferson et al.   Cell Death & Disease

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

(2012) N Takahashi et al.   Cell Death & Disease

Dendritic cell depletion exacerbates acetaminophen hepatotoxicity

(2011) Michael K. Connolly et al.   HEPATOLOGY

Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury

(2011) C. David Williams et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Histology of Autoimmune Hepatitis and its Variants

(2010) Maha Guindi   Clinics in Liver Disease

Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis

(2009) Weidong Han et al.   APOPTOSIS

Acetaminophen Hepatotoxicity and Acute Liver Failure

(2009) Linda J. Chun et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis

(2009) M. Nakaya et al.   JOURNAL OF IMMUNOLOGY

TLR-9 Activation Aggravates Concanavalin A-Induced Hepatitis via Promoting Accumulation and Activation of Liver CD4+ NKT Cells

(2009) W. Jiang et al.   JOURNAL OF IMMUNOLOGY

Autoimmune Hepatitis and Liver Transplantation: Indications, Results, and Management of Recurrent Disease

(2009) Dhiraj Tripathi et al.   SEMINARS IN LIVER DISEASE

Influence of genes, sex, age and environment on the onset of autoimmune hepatitis

(2009) Kathie Béland et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Differential Roles of JNK in ConA/GalN and ConA-Induced Liver Injury in Mice

(2008) Hong-Min Ni et al.   AMERICAN JOURNAL OF PATHOLOGY

Innate immunity and acetaminophen-induced liver injury: Why so many controversies?

(2008) Hartmut Jaeschke   HEPATOLOGY

Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxide

(2008) Mary Jane Masson et al.   HEPATOLOGY

Autoimmune liver serology: Current diagnostic and clinical challenges

(2008) Dimitrios P Bogdanos et al.   WORLD JOURNAL OF GASTROENTEROLOGY