Loss of STAT1 protects hair cells from ototoxicity through modulation of STAT3, c-Jun, Akt, and autophagy factors

Ginkgolide B protects against cisplatin-induced ototoxicity: enhancement of Akt–Nrf2–HO-1 signaling and reduction of NADPH oxidase

(2015) Weijun Ma et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Erdosteine protects HEI-OC1 auditory cells from cisplatin toxicity through suppression of inflammatory cytokines and induction of Nrf2 target proteins

(2015) Se-Jin Kim et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Bmi1 regulates auditory hair cell survival by maintaining redox balance

(2015) Y Chen et al.   Cell Death & Disease

All Akt Isoforms (Akt1, Akt2, Akt3) Are Involved in Normal Hearing, but Only Akt2 and Akt3 Are Involved in Auditory Hair Cell Survival in the Mammalian Inner Ear

(2015) Yves Brand et al.   PLoS One

Beclin-1-mediated autophagy protects spinal cord neurons against mechanical injury-induced apoptosis

(2014) Zhen-Yu Wang et al.   APOPTOSIS

Rapamycin alleviates cisplatin-induced ototoxicity in vivo

(2014) Bin Fang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Otoprotective Properties of Mannitol Against Gentamicin Induced Hair Cell Loss

(2014) John William Wood et al.   OTOLOGY & NEUROTOLOGY

Lysosomal Interaction of Akt with Phafin2: A Critical Step in the Induction of Autophagy

(2014) Mami Matsuda-Lennikov et al.   PLoS One

Downstream Targets of Lmo4 Are Modulated by Cisplatin in the Inner Ear of Wistar Rats

(2014) Samson Jamesdaniel   PLoS One

JAK2/STAT3 Inhibition Attenuates Noise-Induced Hearing Loss

(2014) Teresa Wilson et al.   PLoS One

Bax, Bcl2, and p53 Differentially Regulate Neomycin- and Gentamicin-Induced Hair Cell Death in the Zebrafish Lateral Line

(2013) Allison B. Coffin et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Efficacy of three drugs for protecting against gentamicin-induced hair cell and hearing losses

(2012) E Bas et al.   BRITISH JOURNAL OF PHARMACOLOGY

The stat3/socs3a Pathway Is a Key Regulator of Hair Cell Regeneration in Zebrafish stat3/socs3a Pathway: Regulator of Hair Cell Regeneration

(2012) J. Liang et al.   JOURNAL OF NEUROSCIENCE

Loss of STAT1 in Bone Marrow-Derived Cells Accelerates Skeletal Muscle Regeneration

(2012) Yan Gao et al.   PLoS One

Early otic development depends on autophagy for apoptotic cell clearance and neural differentiation

(2012) M R Aburto et al.   Cell Death & Disease

Cisplatin ototoxicity involves cytokines and STAT6 signaling network

(2011) Hyung-Jin Kim et al.   CELL RESEARCH

STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy

(2011) J. McCormick et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation

(2011) T Kaur et al.   Cell Death & Disease

c-Jun, at the crossroad of the signaling network

(2011) Qinghang Meng et al.   Protein & Cell

Stress and Survival Pathways in the Mammalian Cochlea

(2010) Antje Caelers et al.   AUDIOLOGY AND NEURO-OTOLOGY

Epicatechin protects the auditory organ by attenuating cisplatin-induced ototoxicity through inhibition of ERK

(2010) J.S. Lee et al.   TOXICOLOGY LETTERS

Cisplatin-Induced Hair Cell Death Requires STAT1 and Is Attenuated by Epigallocatechin Gallate

(2009) N. C. Schmitt et al.   JOURNAL OF NEUROSCIENCE

Proapoptotic effects of NF-κB on cisplatin-induced cell death in auditory cell line

(2008) Won-Ho Chung et al.   ACTA OTO-LARYNGOLOGICA

Evidence that Cisplatin-induced Auditory Damage is Attenuated by Downregulation of Pro-inflammatory Cytokines Via Nrf2/HO-1

(2008) HongSeob So et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Ups and downs: The STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling

(2008) Gabriella Regis et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY