Bax, Bcl2, and p53 Differentially Regulate Neomycin- and Gentamicin-Induced Hair Cell Death in the Zebrafish Lateral Line

Profiling drug-induced cell death pathways in the zebrafish lateral line

(2013) Allison B. Coffin et al.   APOPTOSIS

Kinocilia Mediate Mechanosensitivity in Developing Zebrafish Hair Cells

(2012) Katie S. Kindt et al.   DEVELOPMENTAL CELL

Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin

(2012) Anna L. Vlasits et al.   HEARING RESEARCH

Rheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells

(2012) Arminda Suli et al.   PLoS One

Gentamicin Rapidly Inhibits Mitochondrial Metabolism in High-Frequency Cochlear Outer Hair Cells

(2012) Heather C. Jensen-Smith et al.   PLoS One

Interaction of the ARF tumor suppressor with cytosolic HSP70 contributes to its autophagy function

(2011) Julia Pimkina et al.   CANCER BIOLOGY & THERAPY

Inhibition of p73 function by Pifithrin-α as revealed by studies in zebrafish embryos

(2011) William Davidson et al.   CELL CYCLE

The transcription-independent mitochondrial p53 program is a major contributor to Nutlin-induced apoptosis in tumor cells

(2011) Angelina V. Vaseva et al.   CELL CYCLE

New developments in aminoglycoside therapy and ototoxicity

(2011) Jing Xie et al.   HEARING RESEARCH

Hair Cell Toxicity in Anti-cancer Drugs: Evaluating an Anti-cancer Drug Library for Independent and Synergistic Toxic Effects on Hair Cells Using the Zebrafish Lateral Line

(2011) Yoshinobu Hirose et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

In vitro protection of auditory hair cells by salicylate from the gentamicin-induced but not neomycin-induced cell loss

(2011) Birgit Mazurek et al.   NEUROSCIENCE LETTERS

Cellular mechanisms of aminoglycoside ototoxicity

(2010) Mark E Warchol   Current Opinion in Otolaryngology & Head and Neck Surgery

Regulation of Mitochondrial Apoptotic Events by p53-mediated Disruption of Complexes between Antiapoptotic Bcl-2 Members and Bim

(2010) Jie Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line

(2010) Allison B. Coffin et al.   Zebrafish

Bcl-2 Gene Therapy Prevents Aminoglycoside-Induced Degeneration of Auditory and Vestibular Hair Cells

(2009) Susanna C. Pfannenstiel et al.   AUDIOLOGY AND NEURO-OTOLOGY

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Pifithrin-α protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53

(2009) D Sohn et al.   CELL DEATH AND DIFFERENTIATION

Hsp70 inhibits aminoglycoside-induced hearing loss and cochlear hair cell death

(2009) Mona Taleb et al.   CELL STRESS & CHAPERONES

Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line

(2009) Allison B. Coffin et al.   HEARING RESEARCH

Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways

(2009) Kelly N. Owens et al.   HEARING RESEARCH

Cytoplasmic p53 and Activated Bax Regulate p53-dependent, Transcription-independent Neural Precursor Cell Apoptosis

(2009) Ying Geng et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

A Small Molecule Inhibitor of Inducible Heat Shock Protein 70

(2009) J. I-Ju Leu et al.   MOLECULAR CELL

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Time course of apoptotic cell death in guinea pig cochlea following intratympanic gentamicin application

(2008) Mitsuya Suzuki et al.   ACTA OTO-LARYNGOLOGICA

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals

(2008) C A Jette et al.   CELL DEATH AND DIFFERENTIATION

Comparison of activated caspase detection methods in the gentamicin-treated chick cochlea

(2008) Christina L. Kaiser et al.   HEARING RESEARCH

Do we still need the aminoglycosides?

(2008) Emanuele Durante-Mangoni et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Hsp70 Inhibits Aminoglycoside-Induced Hair Cell Death and is Necessary for the Protective Effect of Heat Shock

(2008) Mona Taleb et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

The p53 family and programmed cell death

(2008) E C Pietsch et al.   ONCOGENE

Bcl-2 genes regulate noise-induced hearing loss

(2007) Daisuke Yamashita et al.   JOURNAL OF NEUROSCIENCE RESEARCH