Identification of thiostrepton as a novel therapeutic agent that targets human colon cancer stem cells

FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells

(2015) Wen-Tai Chiu et al.   Oncotarget

HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib

(2015) Alberto Ramírez et al.   Oncotarget

Colorectal cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Significance of mTOR Signaling and Its Inhibitor Against Cancer Stem-Like Cells in Colorectal Cancer

(2013) Zerong Cai et al.   ANNALS OF SURGICAL ONCOLOGY

A phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503)

(2013) S Sahebjam et al.   BRITISH JOURNAL OF CANCER

Colorectal cancer

(2013) Hermann Brenner et al.   LANCET

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

(2013) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maintenance of the stemness in CD44+ HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression

(2013) Sy-Yeuan Ju et al.   Stem Cell Research

MELK-Dependent FOXM1 Phosphorylation is Essential for Proliferation of Glioma Stem Cells

(2013) Kaushal Joshi et al.   STEM CELLS

Applications of Connectivity Map in drug discovery and development

(2012) Xiaoyan A. Qu et al.   DRUG DISCOVERY TODAY

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Expression Analysis of Middle Eastern Colorectal Cancer Reveals FOXM1 as a Novel Target for Cancer Therapy

(2011) Shahab Uddin et al.   AMERICAN JOURNAL OF PATHOLOGY

Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistance

(2011) Marek Mraz et al.   BRITISH JOURNAL OF HAEMATOLOGY

FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis

(2011) Nu Zhang et al.   CANCER CELL

A Novel FoxM1-Caveolin Signaling Pathway Promotes Pancreatic Cancer Invasion and Metastasis

(2011) C. Huang et al.   CANCER RESEARCH

Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells

(2011) Bin Bao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A Molecular Screening Approach to Identify and Characterize Inhibitors of Glioblastoma Stem Cells

(2011) K. Visnyei et al.   MOLECULAR CANCER THERAPEUTICS

FoxM1 Mediates Resistance to Herceptin and Paclitaxel

(2010) Janai R. Carr et al.   CANCER RESEARCH

Novel anticancer compounds induce apoptosis in melanoma cells

(2010) Uppoor G. Bhat et al.   CELL CYCLE

Wild-type p53 protects normal cells against apoptosis induced by thiostrepton

(2010) Marianna Halasi et al.   CELL CYCLE

A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer

(2010) Roberta Pang et al.   Cell Stem Cell

Bone Morphogenetic Protein 4 Induces Differentiation of Colorectal Cancer Stem Cells and Increases Their Response to Chemotherapy in Mice

(2010) Ylenia Lombardo et al.   GASTROENTEROLOGY

FOXM1 Confers Acquired Cisplatin Resistance in Breast Cancer Cells

(2010) J. M.-M. Kwok et al.   MOLECULAR CANCER RESEARCH

Foxm1 transcription factor is required for maintenance of pluripotency of P19 embryonal carcinoma cells

(2010) Zhongqiu Xie et al.   NUCLEIC ACIDS RESEARCH

CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts

(2009) E Marangoni et al.   BRITISH JOURNAL OF CANCER

EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance

(2009) M.-L. Suva et al.   CANCER RESEARCH

Critical Role and Regulation of Transcription Factor FoxM1 in Human Gastric Cancer Angiogenesis and Progression

(2009) Q. Li et al.   CANCER RESEARCH

Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis

(2009) E. H. Huang et al.   CANCER RESEARCH

Chemoresistant Colorectal Cancer Cells, the Cancer Stem Cell Phenotype, and Increased Sensitivity to Insulin-like Growth Factor-I Receptor Inhibition

(2009) N. A. Dallas et al.   CANCER RESEARCH

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

(2009) Emmanuelle Charafe-Jauffret et al.   CANCER RESEARCH

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Involvement of Nrf2 activation in resistance to 5-fluorouracil in human colon cancer HT-29 cells

(2009) Hanane Akhdar et al.   EUROPEAN JOURNAL OF CANCER

Thiazole Antibiotics Target FoxM1 and Induce Apoptosis in Human Cancer Cells

(2009) Uppoor G. Bhat et al.   PLoS One

FoxM1 Is a General Target for Proteasome Inhibitors

(2009) Uppoor G. Bhat et al.   PLoS One

CD133+CD44+ Population Efficiently Enriches Colon Cancer Initiating Cells

(2008) Naotsugu Haraguchi et al.   ANNALS OF SURGICAL ONCOLOGY

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

FoxM1 inhibitors as potential anticancer drugs

(2008) Andrei L Gartel   EXPERT OPINION ON THERAPEUTIC TARGETS

Characterization of a subpopulation of colon cancer cells with stem cell-like properties

(2008) Peter Chu et al.   INTERNATIONAL JOURNAL OF CANCER

Colorectal Cancer Stem Cells Are Enriched in Xenogeneic Tumors Following Chemotherapy

(2008) Scott J. Dylla et al.   PLoS One